87 results on '"Manufacturing capability"'
Search Results
2. Investigation on microstructure control of in-situ synthesized high-performance Cf/SiC composites
- Author
-
Zhongliang Lu, Cao Jiwei, Dichen Li, Li Sai, Zhongrui Wang, Bingheng Lu, and Kiao Miao
- Subjects
In situ ,Fabrication ,Materials science ,Mechanical Engineering ,Composite number ,Metals and Alloys ,02 engineering and technology ,engineering.material ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Microstructure ,01 natural sciences ,0104 chemical sciences ,Manufacturing capability ,Fracture toughness ,stomatognathic system ,Coating ,Mechanics of Materials ,visual_art ,Materials Chemistry ,engineering ,visual_art.visual_art_medium ,Ceramic ,Composite material ,0210 nano-technology - Abstract
A new type of pure carbon fiber (C f ) preform with complex shape was prepared by gel-casting. C f /SiC composite with high performance was rapidly prepared by reactive melt infiltration (RMI). The microstructure which determined the mechanical properties of the C f /SiC composites could be controlled by in-situ fiber coating preparation process. The fracture toughness of the C f /SiC composite with SiC and PyC coating, 8.3 ± 1.5 MPa m 1/2 , was far superior to pure SiC ceramic prepared by RMI. This method showed excellent manufacturing capability and remarkable potential in fabrication of C f /SiC composites with complex shape and high mechanical performance.
- Published
- 2019
- Full Text
- View/download PDF
3. Unveiling additive manufacturing with metal powders industry trends with technology interventions and competitive landscape as frame of reference
- Author
-
Sunil Hebbalkar
- Subjects
Engineering ,business.industry ,Mechanical Engineering ,medicine.medical_treatment ,Aerospace Engineering ,Traction (orthopedics) ,Frame of reference ,Manufacturing engineering ,Manufacturing capability ,Manufacturing sector ,Mechanics of Materials ,Automotive Engineering ,medicine ,General Materials Science ,Design methods ,business - Abstract
In the past few years, additive manufacturing with metal powders industry has gained rapid traction in the metal manufacturing sector, prominently in those regions where conventional manufacturing encounters limitations related to manufacturing capability and design methodology.
- Published
- 2018
- Full Text
- View/download PDF
4. MANUFACTURING CAPABILITY OF Al–Li 1441 ALLOY DETAILS
- Author
-
A.V. Klychеv, N.Yu. Serebrennikova, M.D. Panteleev, O.Yu. Kozlova, V. V. Antipov, N.N. Osipov, and Yu.N. Nefedova
- Subjects
Materials science ,Alloy ,Metallurgy ,engineering ,General Medicine ,engineering.material ,Manufacturing capability - Published
- 2018
- Full Text
- View/download PDF
5. Evaluating the Past, Present, and Future of Regenerative Medicine: A Global View
- Author
-
BayonYves, E van DykeMark, DuprazAnne, A VertèsAlain, H MayMichael, and RonfardVincent
- Subjects
0301 basic medicine ,Clinical Trials as Topic ,Engineering ,Internationality ,Standard of care ,business.industry ,Biomedical Engineering ,Bioengineering ,Regenerative Medicine ,Biochemistry ,Regenerative medicine ,Hype cycle ,Manufacturing capability ,Biomaterials ,03 medical and health sciences ,030104 developmental biology ,Animals ,Humans ,Cooperative Behavior ,Marketing ,business ,Reimbursement - Abstract
“Evaluating the Past and Present of Regenerative Medicine (RM)” was the first part of an Industry Symposium dedicated to the subject during the 2015 TERMIS World Congress in Boston. This working session presented a critical review of the current RM landscape in Europe and North America with possible projections for the future. Interestingly, the RM development cycle seems to obey the Gartner hype cycle, now at the enlightenment phase, after past exaggerated expectations and discouragements, as suggested by increasing numbers of clinical trials and recent market approvals of RM solutions in both Europe (Glybera and Holoclar® from Chiesi Pharma and Strimvelis® from GSK) and Japan (Remestemcel-L from Mesoblast®). The successful commercial translation of RM research is governed by five major drivers: (i) fully validated manufacturing capability for autologous or allogeneic products, (ii) reimbursement for targeted clinical indications with high and demonstrable medico-economic benefits versus standard of care...
- Published
- 2017
- Full Text
- View/download PDF
6. Cumulative manufacturing capabilities in Europe: Integrating sustainability into the sand cone model
- Author
-
Stefan Gold, Reinhold Schodl, and Gerald Reiner
- Subjects
Civil society ,Engineering ,Renewable Energy, Sustainability and the Environment ,business.industry ,Strategy and Management ,Supply chain ,05 social sciences ,Environmental resource management ,Environmental economics ,Cone (formal languages) ,Industrial and Manufacturing Engineering ,Manufacturing capability ,Contingency theory ,0502 economics and business ,Sustainability ,050501 criminology ,media_common.cataloged_instance ,European union ,business ,Contingency ,050203 business & management ,0505 law ,General Environmental Science ,media_common - Abstract
The purpose of this paper is to investigate the development of manufacturing capabilities in Central and Eastern Europe. In particular, top management's competitive priorities, plants' manufacturing strategies, and plants' manufacturing performances are compared between old and new European Union member states. Internationally collected data are compared using various analyses of covariance. The findings are interpreted against the background of the sand cone model, which is extended by integrating sustainability twice—that is, in its proactive and reactive forms. The results indicate that old and new member states dwell on different steps of cumulative manufacturing capability development. It is hypothesized that this can be attributed to differing labor costs; the requirements imposed by supply chains; and the pressure from stakeholders, such as civil society organizations. Our study responds to various calls to refine the sand cone model through the use of contingency theory by considering the operating conditions of plants in the two country groups as environmental contingency factors.
- Published
- 2017
- Full Text
- View/download PDF
7. A Capability-Driven Dynamic Federal Collaborative Design Methodology to Support the Inter-enterprise Development of Ordnance Equipment
- Author
-
Jun Ji, Wei Wei, Wenjun Liu, Jianxin Yang, and Lindong Zhang
- Subjects
0209 industrial biotechnology ,Engineering ,business.industry ,media_common.quotation_subject ,02 engineering and technology ,Business model ,Manufacturing capability ,020901 industrial engineering & automation ,Development (topology) ,020204 information systems ,0202 electrical engineering, electronic engineering, information engineering ,Systems engineering ,General Earth and Planetary Sciences ,Quality (business) ,Collaborative design ,Architecture ,business ,Rapid response ,Blossom algorithm ,General Environmental Science ,media_common - Abstract
Facing the challenge of rapid response to customer personalized demand and developing high quality competitive ordnance equipment, the paper proposes a capability-driven dynamic federal collaborative design methodology to support inter-enterprise development. The core is dynamic constructing collaborative development capability federation (CDCF) by combinatorial optimizing and intelligent disposing various inter-enterprise designing and manufacturing capability. The paper presents the business model and capability models of CDCF and focuses on the capability constraints-based constructing method and requirement-capability matching algorithm of CDCF. Applying service-oriented architecture (SOA)-based integrating method, the inter-enterprise federal collaborative development platform was constructed. Finally, a heavy military vehicle inter-enterprise collaborative design engineering application case validates the effectiveness and feasibility of the method.
- Published
- 2017
- Full Text
- View/download PDF
8. The Horten Ho-229 Aircraft [History Column]
- Author
-
Hugh Griffiths
- Subjects
Engineering ,Aeronautics ,Space and Planetary Science ,business.industry ,World War II ,Airframe ,Aerospace Engineering ,Electrical and Electronic Engineering ,business ,Manufacturing capability - Abstract
The subject of this column is a quite remarkable German aircraft from World War II (WW2): the Horten Ho-229. This was a single-seat fighter/bomber aircraft with a steel and laminated plywood airframe, powered by two turbojet engines, and designed and built by the Horten brothers, Walter and Reimer. Its maximum speed was close to 1000 km/h. It looks for all the world like a modern-day stealth aircraft - but from 75 years ago. A prototype aircraft flew in test flights in February 1945 - just three months before the end of WW2 in Europe. The results were encouraging, but there was no time and no manufacturing capability to develop it to operational status. The prototype was recovered as the Allies overran Germany, and now-declassified documents in the British National Archives show that the airframe was carefully inspected and the performance assessed. It is not clear how much of this information may have been used in the design of the Northrop XB-35 (1946) and YB-49 (1947) "flying wing" aircraft. The prototype aircraft lay in storage for many years, but has now been taken to the Smithsonian Udvar-Hazy museum, close to Dulles airport, VA, USA, where it is being restored.
- Published
- 2021
- Full Text
- View/download PDF
9. The General Design and Technology Innovations of CAP1400
- Author
-
Zheng Mingguang, Shentu Jun, Qiu Zhongming, Lin Tian, Yan Jinquan, and Wang Xujia
- Subjects
Engineering ,General Chemical Engineering ,Mechanical engineering ,02 engineering and technology ,Intellectual property ,Manufacturing capability ,law.invention ,CAP1400 ,0203 mechanical engineering ,law ,Architecture ,0202 electrical engineering, electronic engineering, information engineering ,Engineering, Geological ,Mining & Mineral Processing ,Technology innovation ,Engineering, Petroleum ,Transportation Science & Technology ,General Engineering ,Forestry ,Geology ,Manufacturing engineering ,Engineering, Mechanical ,020303 mechanical engineering & transports ,Food Science & Technology ,General design ,Computer Science, Interdisciplinary Applications ,Design and Technology ,Engineering, Chemical ,Engineering, Civil ,Environmental Engineering ,General Computer Science ,Safety design ,020209 energy ,Materials Science (miscellaneous) ,Energy Engineering and Power Technology ,Engineering, Multidisciplinary ,Materials Science, Multidisciplinary ,Advanced passive technology ,Mechanics ,Nuclear power plant ,Engineering, Ocean ,China ,Nuclear Science & Technology ,Engineering, Aerospace ,Engineering, Biomedical ,business.industry ,Pressurized water reactor ,Engineering, Environmental ,Engineering, Electrical & Electronic ,Optics ,Engineering, Manufacturing ,lcsh:TA1-2040 ,Localization ,Engineering, Industrial ,Metallurgy & Metallurgical Engineering ,business ,Agricultural Engineering ,lcsh:Engineering (General). Civil engineering (General) ,Environmental Sciences - Abstract
The pressurized water reactor CAP1400 is one of the sixteen National Science and Technology Major Projects. Developed from China's nuclear R&D system and manufacturing capability, as well as AP1000 technology introduction and assimilation, CAP1400 is an advanced large passive nuclear power plant with independent intellectual property rights. By discussing the top design principle, main performance objectives, general parameters, safety design, and important improvements in safety, economy, and other advanced features, this paper reveals the technology innovation and competitiveness of CAP1400 as an internationally promising Gen-III PWR model. Moreover, the R&D of CAP1400 has greatly promoted China's domestic nuclear power industry from the Gen-II to the Gen-III level.
- Published
- 2016
10. Manufacturing Capability, Manufacturing Strategy and Performance of Indonesia Automotive Component Manufacturer
- Author
-
Alan Dwi Wibowo and Rahmat Nurcahyo
- Subjects
Manufacturing Capability ,Engineering ,business.industry ,Manufacturing Strategy ,Performance ,Automotive Component Manufacturer ,Integrated Computer-Aided Manufacturing ,Automotive industry ,ComputerApplications_COMPUTERSINOTHERSYSTEMS ,Automotive engineering ,Manufacturing engineering ,Manufacturing capability ,Computer-integrated manufacturing ,Manufacturing ,Component (UML) ,General Earth and Planetary Sciences ,Advanced manufacturing ,Advanced product quality planning ,business ,General Environmental Science - Abstract
Automotive industry is believed to be the pioneer in pushing the growth of manufacturing industry in Indonesia. By implementing manufacturing strategy, the industry will get its performance improved. Automotive component manufacturer is an important part of automotive industry. This research discusses the relationship between influential variables with performance in Indonesia automotive component manufacturer namely manufacturing capability and manufacturing strategy. A model is developed and data are collected from automotive component manufacturers around Jakarta area. Data is processed using Structural Equation Modeling (SEM). The result shows that manufacturing capability significantly influences manufacturing strategy while manufacturing strategy also significantly influences performance of Indonesia automotive component manufacturer.
- Published
- 2015
- Full Text
- View/download PDF
11. Eco-effective Changeovers; Changing a Burden into a Manufacturing Capability
- Author
-
Steve Evans and Z.E. Gungor
- Subjects
Engineering ,Changeovers ,business.industry ,setup operations ,Changeover ,Environmental economics ,sustainable manufacturing ,Water consumption ,Manufacturing capability ,eco-effective changeovers ,setup time reduction ,Product (business) ,Value (economics) ,Sustainability ,General Earth and Planetary Sciences ,Production (economics) ,Operations management ,Economic impact analysis ,business ,cleaning operations ,General Environmental Science - Abstract
Changeovers stand as a critical operation in the manufacturing companies, however in their current state with significant economic and environmental impacts they are more of a burden then a capability. Market pressures and sustainability requirements soon will push companies even harder to convert this burden into a manufacturing capability. Purpose of this paper to investigate the value definition of changeovers, type of impacts and possible improvement opportunities from an industrial perspective. Due to the lack of data availability on changeover impacts in the current literature, a case-study was conducted through interviews and onsite observations. Current findings indicate that, changeovers may be considered as value adding in some cases. Moreover, from an environmental perspective water consumption, wastewater treatment, energy use, chemical use and product loss were the type of impacts that were frequently brought up, whereas loss of production time was highlighted as the main economic impact. Additionally, companies believe that both design and operational changes can provide improvements for their current systems. Current findings represent the issues within the type of industries included in this early stage of the study and therefore may change in the later stages of the project. This paper highlights important aspects of changeover operations that are commonly neglected in industrial practice while improvements towards these aspects could provide substantial economic benefits while improving companies’ environmental performance.
- Published
- 2015
- Full Text
- View/download PDF
12. Dynamic Manufacturing Capability Assessment of Industrial Robots Based on Feedback Information in Cloud Manufacturing
- Author
-
Wenjun Xu, Duc Truong Pham, Zude Zhou, Zeyu Zhang, and Quan Liu
- Subjects
Engineering ,Computer-integrated manufacturing ,business.industry ,Process development execution system ,Robot ,Cloud manufacturing ,business ,MATLAB ,computer ,Reliability (statistics) ,Manufacturing engineering ,computer.programming_language ,Manufacturing capability - Abstract
With the development of information and computer network technology, cloud manufacturing has been developing rapidly, industrial robots (IRs) as a vital symbol and an advanced technology of manufacturing industry, in scheduling service, the constantly changing information data will result in the corresponding vary of the manufacturing capability. Under a fixed constraint of some capability service request, this will decrease the number of the optimal solutions and provide the inaccurate service to users. So it is important to make the manufacturing capability stable and obtain more optimal solutions to satisfy the constraint, thus the dynamic assessment of manufacturing capability based on information feedback is investigated in this paper. A set of indicators is established considering the IRs’ manufacturing capability and a new dynamic assessment model is proposed to achieve the actual data and the expected data information feedback, using the “normal distribution” model, which can correct the assessment weight. By the way, a case study is simulated in the MATLAB, which shows the reliability and reasonability of this method in evaluate the manufacturing capability in IR.
- Published
- 2017
- Full Text
- View/download PDF
13. The Effect of Optimum Number of Kanbans in just in Time Production System to Manufacturing Performance
- Author
-
Noriah Yusoff, Nurul Hayati Abdul Halim, Ahmed Jaffar, and Ahmad Naufal Adnana
- Subjects
Product (business) ,Engineering ,Stock level ,business.industry ,Control (management) ,Kanban ,General Medicine ,business ,Manufacturing engineering ,Lead time ,Material flow ,Production system ,Manufacturing capability - Abstract
This paper discusses a method to determine optimum numbers of kanban in Just In Time production system and analyzes effect of optimum numbers of kanban to manufacturing performance. Method to determine kanban numbers was carried out by designing kanban flow based current situation, gathering relevant parameter on floor and company database, and calculating of kanban quantity through basic mathematical model. The basic mathematical model of kanban is derived according to designated kanban flow in JIT production system. The optimum number of kanbans would control and regulate material flow in manufacturing, thus JIT is achieved. As a result, product lead time and inventory stock level are improved. The conclusion is that an appropriate determination numbers of kanban could lead to optimizing manufacturing capability.
- Published
- 2013
- Full Text
- View/download PDF
14. Maintaining design intent for aircraft manufacture
- Author
-
Trevor T. Robinson, Danielle Soban, Rajkumar Roy, Cecil Armstrong, Mark Price, Adrian Murphy, and Roisin McConnell
- Subjects
Engineering ,Abstract design ,business.industry ,Mechanical Engineering ,Novelty ,CAD ,Industrial and Manufacturing Engineering ,Manufacturing engineering ,Manufacturing capability ,Original intent ,Design intent ,Work (electrical) ,Systems engineering ,Product (category theory) ,business - Abstract
Design and manufacture of aircraft requires deep multi-disciplinary understanding of system behaviour. The intention of the designer can get lost due to the many changes occurring to the product and the inability of the methods and tools used to capture it. Systems engineering and optimisation tools underpin industrial approaches to design, but are not without issue. The challenge is to find a route from concept to manufacture which enables designers to maintain their original intent. The novelty in this work is that the parameterisation used to build the CAD model reflects the manufacturing capability, ensuring design intent is maintained from concept to manufacture.
- Published
- 2013
- Full Text
- View/download PDF
15. Detailed placement in advanced technology nodes: A survey
- Author
-
Yibo Lin, David Z. Pan, and Bei Yu
- Subjects
010302 applied physics ,Engineering ,business.industry ,Emerging technologies ,computer.internet_protocol ,Distributed computing ,Multiprotocol Label Switching ,02 engineering and technology ,Resolution (logic) ,01 natural sciences ,020202 computer hardware & architecture ,Manufacturing capability ,0103 physical sciences ,Limit (music) ,0202 electrical engineering, electronic engineering, information engineering ,Electronic engineering ,New device ,Layer (object-oriented design) ,business ,Lithography ,computer - Abstract
With the continued scaling to emerging technology nodes, modern circuit designs in nanometer era introduce many strict or even unprecedented design constraints and challenges. On one hand, conventional 193i wavelength lithography has pushed to its resolution limit, and the gap between manufacturing capability and design expectation becomes more critical. On the other hand, new metal layer (e.g. middle-of-line layers) as well as new device layer rules become more complex and restricted. We argue that detailed placement is the appropriate stage to consider the emerging manufacturing and design rule constraints. In this paper, we discuss sophisticated design constraints and challenges in emerging technology nodes, and survey the state-of-the-art detailed placement solutions and methodologies to overcome these challenges.
- Published
- 2016
- Full Text
- View/download PDF
16. Research on the Evaluation Index System of Technological Innovation Capability in Cement Industry
- Author
-
Tian Hai Hua and Da Qi Xu
- Subjects
Engineering ,Index system ,Technological change ,business.industry ,Process (engineering) ,media_common.quotation_subject ,Innovation management ,General Medicine ,Manufacturing engineering ,Manufacturing capability ,System model ,Promotion (rank) ,Process theory ,business ,media_common - Abstract
Combinating the process theory and system theory organically, this paper views enterprise’s technological innovation as a continuously improved system process. It builds a system model for the evaluation of technological innovation capability based on the view of process. Considering the features of cement industry, the technological innovation capabilities in cement industry are divided into innovation management capability, innovation input capability, research & development capability, manufacturing capability, marketing promotion capability and innovation output capability. And we propose a comprehensive and complete evaluation index system of cement industry’s technological innovation capability and provide a ruler for the evaluation of cement industry’s technological innovation capability
- Published
- 2012
- Full Text
- View/download PDF
17. Trends in Sustainable Design Centered Manufacturing
- Author
-
Steve Hsueh-Ming Wang
- Subjects
Engineering ,Computer-integrated manufacturing ,Scope (project management) ,business.industry ,Integrated Computer-Aided Manufacturing ,Sustainability ,General Engineering ,Sustainable design ,Advanced manufacturing ,business ,Competitive advantage ,Manufacturing engineering ,Manufacturing capability - Abstract
This paper illustrates a new manufacturing capability which is driven by design and sustainability. Several objectified design cases by using or waiting the new insertion of manufacturing technologies have been discussed. The cases of the leading products or systems in the world include Kazuo Kawasaki eyeglasses, Mac ibook, Boeing 787-8, integrated circuit, plasmafication, and information based medicine. The research also forecasts the value increased the activities of design centered manufacturing. After defining the scope of sustainability, an analysis of a strategy of a sustainable organization is also included. The research results predict that the competitive advantages of new products come not only from the advanced manufacturing technologies but also from a sustainable design centered manufacturing approach.
- Published
- 2012
- Full Text
- View/download PDF
18. A Study of Knowledge Transfer on Flexible Manufacturing Capability and Manufacturing Performance
- Author
-
Yunfeng Liu and Jianming Zhou
- Subjects
Engineering ,Empirical research ,Computer-integrated manufacturing ,business.industry ,Integrated Computer-Aided Manufacturing ,Process development execution system ,General Engineering ,Advanced manufacturing ,business ,Knowledge transfer ,Manufacturing engineering ,Manufacturing capability ,Manufacturing execution system - Abstract
As the transferring, application and integration of knowledge can highly improve organizational dynamic manufacturing capability, this paper takes an empirical study to explore the relationships among knowledge transfer, flexible manufacturing capability and manufacturing performance based on questionnaires from 113 advanced manufacturing firms in Pearl River Delta of China by the used of structural equation model method.
- Published
- 2012
- Full Text
- View/download PDF
19. Research on the Knowledge-Based Multi-Dimensional Information Model of Manufacturing Capability in CMfg
- Author
-
Yong Liang Luo, Fei Tao, Lin Zhang, and Kui Ping Zhang
- Subjects
Engineering ,Computer-integrated manufacturing ,business.industry ,Information model ,General Engineering ,Multi dimensional ,Networked manufacturing ,Cloud manufacturing ,Dimension (data warehouse) ,business ,Manufacturing engineering ,Formal description ,Manufacturing capability - Abstract
Cloud manufacturing (CMfg) is a new service-oriented, highly efficient, lowly consumption knowledge based, and intelligent networked manufacturing model. It aims to achieve on-demand use, dynamic collaborative work, and circulation of manufacturing resources and manufacturing capability(MC). In order to achieve the above goal proposed, how to realize the formal description of MC is the key point in CMfg. This paper emphasizes the multi-dimensional information model of MC based on knowledge. According to the requirement and characteristics of manufacturing, the concept and connotation of MC were presented firstly in this paper, then the multi-dimension information model for MC was proposed based on knowledge, it contains three dimensions, such as elements dimension, relationship dimension, evaluation dimension.
- Published
- 2012
- Full Text
- View/download PDF
20. A readiness level approach to manufacturing technology development in the aerospace sector: an industrial approach
- Author
-
Simon Halliday, J Foden, and M J Ward
- Subjects
Technology readiness ,Engineering ,Manufacturing technology ,business.industry ,Mechanical Engineering ,Success factors ,ComputerApplications_COMPUTERSINOTHERSYSTEMS ,Maturity (finance) ,Industrial and Manufacturing Engineering ,Manufacturing engineering ,Manufacturing capability ,Key (cryptography) ,Aerospace ,business - Abstract
The use of readiness levels to describe system maturity has become an increasingly recognizable element of the development of technologies for future products in the aerospace and defence sectors. Technology readiness levels (TRLs), as originally defined by NASA, are now widely used by global organizations to articulate the relative maturity of key generic technologies. The implementation of radically new manufacturing capability can also benefit from such an approach. However, the direct use of TRLs in a manufacturing environment is problematic on the basis that it is hard to interpret them precisely, and because the effectiveness of the technology itself is only one of a number of success factors associated with a successful implementation. For several years now the aerospace industry has recognized the need for a manufacturing specific readiness interpretation to enable the delivery of new capabilities in a defined sequence of events. This paper describes an approach used within a single aerospace organization, Rolls-Royce plc. The framework has been identified as a good practice by the UK Aerospace Design and Manufacturing National Technical Committee.
- Published
- 2011
- Full Text
- View/download PDF
21. Study on Multi-View Model for Cloud Manufacturing
- Author
-
Yong Liang Luo, Lei Ren, Dong Jing He, Fei Tao, and Lin Zhang
- Subjects
Engineering ,business.industry ,Process (engineering) ,media_common.quotation_subject ,General Engineering ,Cloud computing ,Networked manufacturing ,Industrial engineering ,Manufacturing engineering ,Manufacturing capability ,Transformation (function) ,View model ,Cloud manufacturing ,Function (engineering) ,business ,media_common - Abstract
Cloud manufacturing (CMfg) is a new service-oriented, highly efficient, lowly consumption knowledge based, and intelligent networked manufacturing model. It aims to provide theoretical and technical supports for the transformation from production-oriented manufacturing to service-oriented manufacturing [1]. In order to further analyze the connotation and characteristics of CMfg, multi-view models for CMfg are investigated based on [1] and [2] in this paper. The first is the network view model, which describes four kinds of network involved in the running process of CMfg system; the second is the function view model, which describes the functional subsystems of CMfg; the third is the running view model, which represents the running process after a requirement is submitted to CMfg system.
- Published
- 2011
- Full Text
- View/download PDF
22. Manufacturing capability networks: A case study on production allocation decision in the pharmaceutical industry
- Author
-
M. Pellerin, Chee Meng Yap, and Kah-Hin Chai
- Subjects
Product design specification ,Engineering ,Operations research ,business.industry ,Mechanical Engineering ,Legislation ,Multiple-criteria decision analysis ,Industrial and Manufacturing Engineering ,Manufacturing capability ,Risk analysis (engineering) ,Ranking ,Extended enterprise ,Production (economics) ,business ,Pharmaceutical industry - Abstract
This study aims to identify and understand the key factors that need to be considered when deciding production allocation in the pharmaceutical industry as well as to develop a managerial framework to guide the location decision in the same industry. A total of ten case studies have been performed in an international pharmaceutical company based in Singapore over an 8-month period. The case studies revealed that production allocation decisions are largely driven by the desire to maximize benefits through the exploitation as well as the development of manufacturing capabilities at both the plant and network level. The study also identified and detailed the influence of legislation requirements, market, and product specifications on these decisions. It was observed that the degree of influence varies from case to case, resulting in two categories of decision criteria: qualifying (i.e. must meet) and ranking (differentiation) criteria. A framework is created to aid managers to decide the best location, maximizing the overall manufacturing network as well as the single plant capabilities.
- Published
- 2009
- Full Text
- View/download PDF
23. Lonza Cell Therapy
- Author
-
Philip G Vanek
- Subjects
Embryology ,Engineering ,Science research ,business.industry ,Process development ,Bioproducts ,Contract Manufacturing ,Biomedical Engineering ,business ,Commercialization ,Manufacturing engineering ,Manufacturing capability - Abstract
Lonza (SWX: LONN) was founded in 1897 in Valais, Switzerland, on the banks of the Lonza River. With a long history of chemical manufacturing and custom services to the pharmaceutical and chemical industries, its expansion into the biotechnology sector was a response to the growing demand for high-quality reagents and custom manufacturing capabilities to support life science research. The acquisition of the Bioproducts and Biopharmaceuticals Companies of Cambrex in 2007 solidified Lonza’s presence in the life science market and expanded a world-class manufacturing capability to support the commercialization needs of the nascent regenerative medicine market.
- Published
- 2008
- Full Text
- View/download PDF
24. Engineered-to-order Approach for Providing Flexibility in e-Commerce of Mold Parts
- Author
-
Ho-Jin Hwang, Kwang-Sub Jang, Junhwan Kim, Duhwan Mun, and Soonhung Han
- Subjects
Flexibility (engineering) ,0209 industrial biotechnology ,Engineering ,business.industry ,0211 other engineering and technologies ,General Engineering ,Trade pattern ,02 engineering and technology ,E-commerce ,Data dictionary ,medicine.disease_cause ,Manufacturing engineering ,Computer Science Applications ,Manufacturing capability ,020901 industrial engineering & automation ,Order (business) ,Modeling and Simulation ,Mold ,medicine ,business ,021106 design practice & management - Abstract
In the mold parts industry, customers typically place orders for order-made parts with some changes to the design specifications of ready-made parts within the extent of the manufacturing capability of the supplier. Being customized for ready-made parts, existing e-Catalog systems cannot support this trade pattern. To solve this problem, an engineered-to-order (ETO) approach is proposed here, enabling the trade of order-made parts in an e-Catalog system by utilizing the design and manufacturing knowledge of part suppliers. After addressing technological challenges and their solutions, we describe application results of the ETO approach to two types of mold parts — ejector pins and mold bases.
- Published
- 2007
- Full Text
- View/download PDF
25. P-123: Image Sticking Analysis of Different Q-time LC Cell by Machine Vision
- Author
-
C. H. Yu, Andy Chao, and K. T. Huang
- Subjects
Measure (data warehouse) ,Engineering ,Liquid-crystal display ,Machine vision ,business.industry ,media_common.quotation_subject ,ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION ,Manufacturing capability ,law.invention ,Image (mathematics) ,law ,Factory (object-oriented programming) ,Quality (business) ,Computer vision ,Artificial intelligence ,business ,ComputingMethodologies_COMPUTERGRAPHICS ,media_common - Abstract
Image Sticking is one of critical issue in TFT-LCD, since it affects product quality and also shows technical and manufacturing capability of LCD factory. In this paper, we use 2D-CCD and automatic machine to measure image sticking phenomenon. The different Q-time panels are measured to compare the image sticking level. A simple model is also proposed to evaluate the panel quality in this thesis. we can get the image sticking quantity by this kind measurement and realized the effect of different Q-time.
- Published
- 2007
- Full Text
- View/download PDF
26. A Relation Model for Manufacturing Capacity and Information
- Author
-
Li Fei
- Subjects
Engineering ,Quantitative analysis (finance) ,Relation (database) ,business.industry ,Volume (computing) ,Systems engineering ,Production (economics) ,Defining relationship ,Set theory ,business ,Formal representation ,Industrial engineering ,Manufacturing capability - Abstract
Aiming at the difficulty of clearly defining relationship between manufacturing capacity(MC) and information due to high volume of information, this paper presents definitions of MC and production processing capacity , the sub manufacturing capability, by combining existing research. Further, MC is decomposed and represented by adopting set theory, especially production processing capacity and relative information, in details. Based on this, a relation model between MC and information is established. The model could provide support for MC calculation and a ssessment. Last but not least, some manufacturing sub-capacity is calculated using manufacturing information of model, which effectively supports quantitative analysis of any MC and sub-capacity.
- Published
- 2015
- Full Text
- View/download PDF
27. UHV Engineering Practices in China
- Author
-
Zhenya Liu
- Subjects
Engineering ,Power transmission ,Standardization ,Project commissioning ,business.industry ,Electrical engineering ,Systems engineering ,China ,business ,Manufacturing capability - Abstract
Chapter 12 summarizes the general situations of the UHV DC power transmission projects put into operation and under construction in China and their main equipment parameters. It briefly outlines the UHV engineering innovation, experimental base and simulation center construction, system commissioning, standard formulation, domestic equipment manufacturing capability, and large facility transportation.
- Published
- 2015
- Full Text
- View/download PDF
28. A global approach for reducing risks in hydrogenation operations
- Author
-
John Holroyde and Cigdem Karayigitoglu
- Subjects
Engineering ,business.industry ,Process (engineering) ,General Chemical Engineering ,Manufacturing operations ,Safety, Risk, Reliability and Quality ,business ,Good practice ,Manufacturing engineering ,Manufacturing capability - Abstract
Pfizer API manufacturing consists of 16 sites around the world and represents a large manufacturing capability. This network has expanded in recent years through mergers. This community of manufacturing sites represents a wide range of practical knowledge for conducting safe API (active pharmaceutical ingredient) manufacturing. Taking advantage of this wealth of experience, Pfizer manufacturing operations performed a global survey of hydrogenation current practices. From the information gathered, a “Hydrogen and Catalyst Handling Good Practice” guide was developed that covered the facility design and operational practices. The team that developed the “Good Practice” guide is also involved in overseeing the implementation of the recommended practices at all manufacturing sites conducting hydrogenations. © 2005 American Institute of Chemical Engineers Process Saf Prog, 2005
- Published
- 2005
- Full Text
- View/download PDF
29. The Study on the Dynamic Characteristic of High Speed Machine Tool and Experiment Validate
- Author
-
Xiao Dong Wang, Yi Min Zhang, Guang Qi Cai, and Xiu Li Lin
- Subjects
Engineering ,business.product_category ,business.industry ,Mechanical Engineering ,Modal analysis ,media_common.quotation_subject ,Mechanical engineering ,Condensed Matter Physics ,Finite element method ,Manufacturing capability ,Machine tool ,Finite element analysis software ,Mechanics of Materials ,Structure design ,General Materials Science ,Function (engineering) ,business ,media_common - Abstract
One of the important factors resulting in the high-speed machinery performance is its machine tool dynamic characteristic. It will directly influence the final manufacturing capability of the machinery and it is also the important criterion of evaluating machinery performances. Especially, the dynamic characteristic of spindle assembly has large effect on manufacturing capability of machinery. So it is very important both analyzing dynamic-static characteristic of the spindle assembly and machine tool of high-speed machinery and studying the effect to machinery function. Using Finite Element Analysis software did a Finite Element Analysis of spindle assembly of the high-speed machine tool, and some experiments are done to validate the result the Finite Element Analysis results.
- Published
- 2004
- Full Text
- View/download PDF
30. Measuring manufacturing capability for couplers and wavelength division multiplexers
- Author
-
Chien-Wei Wu and Wen Lea Pearn
- Subjects
Engineering ,business.industry ,Mechanical Engineering ,Process capability ,Bandwidth (signal processing) ,Multiplexer ,Industrial and Manufacturing Engineering ,Computer Science Applications ,Manufacturing capability ,Wavelength ,Control and Systems Engineering ,Electronic engineering ,Insertion loss ,Channel spacing ,Quality characteristics ,business ,Software - Abstract
The couplers and wavelength division multiplexers have been widely used in high-speed, high-volume image data transmission systems to provide sufficient bandwidth and smaller channel spacing for greater throughput. In this paper, we develop a method for measuring the manufacturing capability of a process making couplers and wavelength division multiplexers. The proposed method measures the process capability of reproducing product items meeting the manufacturing specifications where multiple product quality characteristics are involved, including the polarization dependent loss, and the insertion loss, which are critical in fiber-optic transmission quality.
- Published
- 2004
- Full Text
- View/download PDF
31. After Action Report: Specific Manufacturing Capability 2014 Evaluated Drill October 29, 2014
- Author
-
V. Scott Barnes
- Subjects
Idaho National Laboratory ,Engineering ,Documentation ,Aeronautics ,Emergency management ,Drill ,business.industry ,Forensic engineering ,business ,Manufacturing capability - Abstract
On October 29, 2014, the Specific Manufacturing Capability (SMC) facility located at the Idaho National Laboratory (INL) conducted its annual evaluated emergency drill. As a result, this after action report is required by DOE O 151.1C, “Comprehensive Emergency Management System.” The SMC facility, in coordination with other onsite organizations, and the Department of Energy Idaho Operations Office (DOE ID) conducted an annual facility emergency drill to demonstrate the ability to implement the requirements of DOE O 151.1C, “Comprehensive Emergency Management System.” The INL contractor, Battelle Energy Alliance, LLC (BEA) in coordination with other onsite organizations, conducted operations and demonstrated proper response measures to mitigate an event and protect the health and safety of onsite personnel, the environment, and property. Report data was collected from multiple sources, including documentation generated during drill response, critiques conducted immediately after terminating the drill, and evaluation critiques.
- Published
- 2014
- Full Text
- View/download PDF
32. Development of questionnaire to assess manufacturing capability along different decision areas
- Author
-
Bhurchand Jain, Usha Ananthakumar, and Gajendra Kumar Adil
- Subjects
Long lasting ,Manufacturing Capability ,Engineering ,Process management ,Manufacturing Decision Area ,Management science ,business.industry ,Questionnaire ,Mechanical Engineering ,Manufacturing Strategy ,Performance ,Industrial and Manufacturing Engineering ,Computer Science Applications ,Manufacturing capability ,Management ,Manufacturing strategy ,Production Competence ,Categorization ,Control and Systems Engineering ,Criterion validity ,Instrument design ,business ,Software ,Reliability (statistics) ,Operations Strategy - Abstract
Superior manufacturing capability provides long lasting competitive benefits to a company in the market. It is thus imperative to have an instrument to assess the manufacturing capability of companies. However, empirically tested and reliable tools for the purpose of evaluation of manufacturing capability along different decision areas are scarcely available in the literature. This paper develops questionnaires based on generally accepted principle of instrument design to assess the manufacturing capabilities along different decision areas for four categorization schemes of manufacturing decision areas reported in the literature. The reliability and validity of all four instruments are assessed through responses from managers of 32 manufacturing units and are found to be satisfactory for most of the factors. The criterion validity is found to be fairly good for all the four instruments.
- Published
- 2014
- Full Text
- View/download PDF
33. Manufacturing Capability Knowledge Modeling for Intelligent Manufacturing Systems
- Author
-
Farhad Ameri and Kristina Shea
- Subjects
Engineering ,Knowledge modeling ,Computer-integrated manufacturing ,business.industry ,Integrated Computer-Aided Manufacturing ,Process development execution system ,Advanced manufacturing ,business ,IDEF0 ,Manufacturing engineering ,Manufacturing capability ,Manufacturing execution system - Published
- 2014
- Full Text
- View/download PDF
34. Enhancing Collaborative Decision-Making Processes Using a Web-Based Application: A Case Study of a UK Precision Engineering SME
- Author
-
Konstantinos Stamatopoulos, Andrew C. Lyons, Jorge E. Hernández, and David Savin
- Subjects
Engineering management ,Engineering ,Production planning ,Precision engineering ,business.industry ,Supply chain ,Web application ,Aerospace ,business ,Manufacturing capability ,Group decision-making ,Renewable energy - Abstract
The precision engineering sector lies at the heart of the UK’s manufacturing capability. Successful precision engineering businesses are required to master process innovation and supply chain solutions. Companies operating in this sector support, amongst others, economy-driving industries such as aerospace, defence, motorsport, nuclear, off-highway equipment, oil and gas and renewable energy. The main companies that constitute this sector are SMEs (or small and medium-sized enterprises). In these types of business environment, the implementation of innovative, collaborative solutions has become a necessary strategy for enhancing SME decision-making processes as well as for improving overall business competitiveness. The aim of the research described in this paper is to present how, by implementing a web and onlinebased collaborative tool, precision engineering SME’s can benefit, and are able to enhance their performance, by improving their production planning processes collaboratively. The research is presented with the help of a description of case study undertaken in a precision engineering SME.
- Published
- 2014
- Full Text
- View/download PDF
35. Mechanism of supply chain coordination cased on dynamic capability framework-the mediating role of manufacturing capabilities
- Author
-
Yezhuang Tian and Tiantian Gao
- Subjects
manufacturing capability ,Engineering ,Process management ,lcsh:T55.4-60.8 ,Strategy and Management ,Supply chain ,media_common.quotation_subject ,Economia i organització d'empreses::Direcció d’operacions::Modelització de transports i logística [Àrees temàtiques de la UPC] ,Logística (Indústria) ,Manufacturing enterprises ,lcsh:Business ,supply chain coordination, dynamic capability, manufacturing capability, enterprise performance ,Industrial and Manufacturing Engineering ,lcsh:Social Sciences ,Business logistics ,ddc:650 ,lcsh:Industrial engineering. Management engineering ,Operations management ,Quality (business) ,media_common ,enterprise performance ,Flexibility (engineering) ,lcsh:Commerce ,supply chain coordination ,Supply chain management ,Mechanism (biology) ,business.industry ,GRASP ,Manufacturing strategy ,lcsh:H ,lcsh:HF1-6182 ,dynamic capability ,business ,lcsh:HF5001-6182 - Abstract
Purpose: A critical issue has been absent from the conversation on supply chain coordination: how supply chain coordination influence the enterprise performance. This research proposes a new vision to research the performance mechanism of supply chain coordination capability as a dynamic capability. Manufacturing capabilities are existed as mediating role. Design/methodology/approach: Data from International Manufacturing Strategy Survey in 2009 is used to verify the mediating model by hierarchical regression analysis. Findings: The results show that supply chain coordination impacts the enterprise performance positively and indirect impacts the enterprise performance through quality, cost, flexibility. Research implications: This study presents an overview of the impact of supply chain coordination and manufacturing capabilities on enterprise performance, giving grasp for further research of the relationships that exist between them. Originality/value: This finding integrates insights from previous research in dynamic capability framework and supply chain management into a generalization and extension of the performance mechanism in manufacturing enterprises.
- Published
- 2014
36. DYNAMIC INTEGRATED PROCESS PLANNING AND SCHEDULING
- Author
-
Qing-Shun Xiao, Hong-Yi Chen, and Chun-Wei R. Lin
- Subjects
Production line ,Engineering ,business.industry ,Production cost ,Real-time computing ,Scheduling (production processes) ,Dynamic priority scheduling ,Industrial and Manufacturing Engineering ,Reliability engineering ,Manufacturing capability ,Production planning ,Production schedule ,Production order ,business - Abstract
Unexpected disturbance to the manufacturing capability and production schedule of a production system may always lead to the stoppage of the production line and delay to fulfill the production order. In order to cope with these disturbances, traditional production planning and control approaches focused on the “localized” problem and only provided limited adjustment of the system. A Dynamic Integrated Process planning and Scheduling system (DIPS) is developed that provides a complete systematic examination to the disturbances. DIPS contains a two-stage, genetic-algorithm-based control mechanism that can dynamically generate both the optimal process plan and production schedule. Statistical optimization technique is adopted to evaluate the performance of DIPS. Simulation results show that DIPS significantly improves the total production cost under all problem domains.
- Published
- 2001
- Full Text
- View/download PDF
37. Decision support for off-line gage evaluation and improving on-line gage usage
- Author
-
Yau-Ren Shiau
- Subjects
Guard (information security) ,Decision support system ,Engineering ,business.industry ,GeneralLiterature_MISCELLANEOUS ,Industrial and Manufacturing Engineering ,Manufacturing capability ,Reliability engineering ,Hardware and Architecture ,Control and Systems Engineering ,business ,Software ,Off line ,Type I and type II errors - Abstract
Many indices for evaluating gage capability have been developed and applied, but these methods are ambiguous to users. By considering both manufacturing capability and gage capability, a mathematical model for the measurement loss cost was developed for dinstinct off-line gage evaluation; however, some measurement loss cost still exists after the gage capability study. On-line usage of a gage is improved by reducing the remaining on-line measurement loss cost with the concept of guard limits. Feasible guard limits can be determined by considering the measurement loss cost resulting from both type I and type II errors. Instead of applying a series of gages to confirm the measurement on every part, unreliable measurement can be screened out in advance by the guard limits. Only the necessary precise inspection needs to be further performed. Rather than applying a better gage with higher cost, the concept of guard limits can also be applied to produce a better or similar effect when adopting a gage that is marginal for its applications. The unsatisfactory on-line measurement loss cost can be further reduced until it is acceptable.
- Published
- 2001
- Full Text
- View/download PDF
38. Planar solid oxide fuel cells: the Australian experience and outlook
- Author
-
Bruce Godfrey, Rohan Gillespie, Roger Bolden, Sukhvinder P.S. Badwal, and Karl Foger
- Subjects
Engineering ,Government ,Renewable Energy, Sustainability and the Environment ,business.industry ,Energy Engineering and Power Technology ,Mechanical engineering ,Intellectual property ,Manufacturing capability ,Shareholder ,Distributed generation ,Position (finance) ,Fuel cells ,Electricity ,Electrical and Electronic Engineering ,Physical and Theoretical Chemistry ,business ,Industrial organization - Abstract
Since 1992, Ceramic Fuel Cells (CFCL) has grown to what is now the largest focussed program globally for development of planar ceramic (solid oxide) fuel cell, SOFC, technology. A significant intellectual property position in know-how and patents has been developed, with over 80 people involved in the venture. Over $A60 million in funding for the activities of the company has been raised from private companies, government-owned corporations and government business-support programs, including from energy — particularly electricity — industry shareholders that can facilitate access to local markets for our products. CFCL has established state-of-the-art facilities for planar SOFC R&D, with their expansion and scaling-up to pilot manufacturing capability underway. We expect to achieve commercial introduction of our market-entry products in 2002, with prototype systems expected to be available from early 2001.
- Published
- 2000
- Full Text
- View/download PDF
39. Advancements in the United States Photovoltaic Program
- Author
-
James E. Rannels
- Subjects
Flexibility (engineering) ,Research program ,Engineering ,Renewable Energy, Sustainability and the Environment ,business.industry ,media_common.quotation_subject ,Photovoltaic system ,Environmental economics ,Solar energy ,Manufacturing capability ,Renewable energy ,Economy ,Quality (business) ,Market development ,business ,media_common - Abstract
The major trends in PV technologies, applications and markets show promise for the future of renewable energy. The 30% growth projected for PV shipments in 1998 appears sustainable if current trends in new markets and applications reinforce and accelerate improvements in PV costs and performance. Through established partnerships and programs, R&D continues to focus on improving efficiency of solar energy systems, increasing manufacturing capability, reducing solar energy systems costs, enhancing reliability and flexibility of PV products, and producing innovations in thin-films and other emerging PV technologies. Continued research and market development in the US and other nations will advance quality and performance standards, and reduce the overall price of PV systems, laying the foundation for large-scale market expansion worldwide.
- Published
- 2000
- Full Text
- View/download PDF
40. The K-1 reusable aerospace vehicle: managing to achieve low cost
- Author
-
Debra Facktor Lepore and George E. Mueller
- Subjects
Transport engineering ,Aerospace vehicle ,Engineering ,business.industry ,Systems engineering ,Aerospace Engineering ,Aerospace ,business ,Reliability (statistics) ,Manufacturing capability - Abstract
Kistler Aerospace Corporation is developing the world's first privately funded, fully reusable aerospace vehicle, the K-1. This vehicle represents a new implementation of proven technologies, designed by an elite, experienced team of engineers and managers and implemented by the best manufacturing capability in the United States. Kistler Aerospace expects to begin commercial operations of the K-1 in 2000. Market researchers predict that during the next decade telecommunications satellite ventures will require launch services for over 1,400 payloads to LEO. This prediction greatly exceeds the current available industry capacity. The K-1 was designed primarily to meet this anticipated growth in demand. Significant progress has been made in constructing the K-1 vehicle fleet. The fully reusable K-1 vehicle is designed to lower the cost of access to space, increase launch reliability, and reduce lead-time-to-launch requirements. The K-1 will offer significant cost benefits and aircraft type reliability based on a proven flight record.
- Published
- 2000
- Full Text
- View/download PDF
41. Manufacturing capability measurement for cellular manufacturing systems
- Author
-
Paul Maropoulos and R. P. Baker
- Subjects
Engineering ,Schedule ,Workstation ,business.industry ,Strategy and Management ,Cellular manufacturing ,Management Science and Operations Research ,Industrial and Manufacturing Engineering ,Reliability engineering ,Manufacturing capability ,law.invention ,Product (business) ,Ranking ,law ,Transparency (graphic) ,business - Abstract
An important element in the design and management of cellular manufacturing systems is the ability to determine capabilities. This paper describes a generic methodology of Capability Analysis (CA) which can be used for the integrated assessment of various capability factors. The main aspect of CA is the ability to compare different factors alongside one-another. This is done by determining priority confidence scores (PCS values) which are capability scores (measures of performance) represented as proportions of required capability scores adjusted to take into account improvement potential, factor importance and financial considerations. CA is used to form a recovery schedule of targets for improvement ranked in order of priority and is produced by ranking the PCS values for each capability level (cell, product, part, workstation and operation). Targets at a higher level can be broken down into more detailed targets at a lower level using the concept of transparency. The workings of CA are demonstrated usi...
- Published
- 1998
- Full Text
- View/download PDF
42. Assessment of U.S. Manufacturing Capability for Next-Generation Wind Turbine Drivetrains
- Author
-
T. Stelhy and J. Cotrell
- Subjects
Engineering ,Wind power ,business.industry ,Supply chain ,Drivetrain ,business ,Turbine ,Manufacturing engineering ,Automotive engineering ,Manufacturing capability - Published
- 2013
- Full Text
- View/download PDF
43. Manufacturing capability of hole reaming with outrunning plastic deformation
- Author
-
Viktor Yaroslavtsev
- Subjects
Engineering ,business.industry ,Forensic engineering ,Mechanical engineering ,General Medicine ,business ,Manufacturing capability - Published
- 2013
- Full Text
- View/download PDF
44. Molecule and Manufacturability Assessment Leading to Robust Commercial Formulation for Therapeutic Proteins
- Author
-
Ranjini Ramachander and Nitin Rathore
- Subjects
Engineering ,business.industry ,Process development ,Process (engineering) ,Biochemical engineering ,business ,Manufacturing engineering ,Manufacturing capability ,Design for manufacturability - Abstract
The transfer of lead molecules from discovery into process development at a relatively fast pace requires a process of candidate selection that assesses if a candidate is not only active and safe but also “manufacturable.” Formulation and process stability of potential candidates help narrow down lead candidates at an early stage, prior to large-scale manufacturing, by a process of rank-ordering properties generated from process and long-term stability studies. Such an assessment of the molecules’ manufacturability is especially useful when binding affinity and bioactivity are comparable among the various candidates under question. This chapter reviews several case studies that explore the utility of early-stage molecule or manufacturability assessments in moving forward therapeutic candidate/s by finely balancing potency and pharmacokinetics with the manufacturing capability of the candidate/s under question.
- Published
- 2013
- Full Text
- View/download PDF
45. Investigating the alternative paradigms of manufacturing competence: an empirical study
- Author
-
Gajendra Kumar Adil, Bhurchand Jain, and Usha Ananthakumar
- Subjects
0209 industrial biotechnology ,Engineering ,Process management ,Strategy and Management ,media_common.quotation_subject ,Integrated Computer-Aided Manufacturing ,Exploratory research ,02 engineering and technology ,Audit ,Industrial and Manufacturing Engineering ,Manufacturing capability ,020901 industrial engineering & automation ,Empirical research ,Originality ,0502 economics and business ,Competence (human resources) ,media_common ,business.industry ,05 social sciences ,Small sample ,Manufacturing engineering ,Computer Science Applications ,Control and Systems Engineering ,business ,050203 business & management ,Software - Abstract
Purpose The purpose of this paper is to explore the relationship of strategic manufacturing effectiveness utilizing the four-stage model of Hayes and Wheelwright (H-W) with overall performance of manufacturing, market alignment and production competence (PC). In addition, it attempts to understand the relationship of strategic manufacturing effectiveness with manufacturing capability development modes, strategic groups of companies and the nature of improvement programs being employed. Design/methodology/approach Structured questionnaire was used to capture data from manufacturing organizations. Responses from managers of 47 Indian manufacturing companies were used to test the seven propositions that were developed to examine the paradigms of manufacturing competence. Findings The analysis revealed that the strategic manufacturing effectiveness of manufacturing companies based on H-W’s four-stage model has significant positive correlation with the overall performance of manufacturing and PC of the company. Further, the analysis substantiated the relationship of strategic manufacturing effectiveness with capability development process and the nature of improvement programs. Research limitations/implications This exploratory study is based on a small sample of manufacturing companies with diversity and hence it may not be representative of all industry sectors. Second, it has used several scales for measuring the relevant constructs which themselves are not proven, hence, the findings should be taken with caution. Originality/value This is an initial research focussing on the relationships among different elements of manufacturing competence such as manufacturing capabilities, PC, manufacturing capability development mode and overall performance of manufacturing with strategic manufacturing effectiveness using H-W model. H-W model was primarily proposed as an audit tool for managers, was hitherto not adequately studied in relation to other paradigms of manufacturing competence.
- Published
- 2016
- Full Text
- View/download PDF
46. A novel process planning approach for hybrid manufacturing consisting of additive, subtractive and inspection processes
- Author
-
Stephen T. Newman, Vimal Dhokia, and Zicheng Zhu
- Subjects
Flexibility (engineering) ,Engineering ,Subtractive color ,Machining ,Computer-integrated manufacturing ,Process (engineering) ,business.industry ,Production (economics) ,Planning approach ,business ,Manufacturing engineering ,Manufacturing capability - Abstract
In recent years, hybrid manufacturing technologies that combine different processes (e.g. additive and subtractive processes) together have gained significant attention. This is due to their ability to capitalise on the advantages of each individual process, whilst minimising their disadvantages. However, there are limited process planning methods that are able to effectively utilise manufacturing resources for hybrid processes. In this paper, a hybrid process entitled iAtractive, combining additive, subtractive and inspection processes, along with part specific process planning is proposed, aiming to provide the designer with greater manufacturing capability and flexibility. This novel process planning approach enables a plastic part to be manufactured in a proper way in terms of process capabilities, production time and material consumption. This approach can be also adopted to remanufacture and reincarnate exiting parts or legacy products into other products. In this paper, the principle and framework of this process planning approach is presented and a test part was manufactured to validate this innovative approach.
- Published
- 2012
- Full Text
- View/download PDF
47. An integrated approach for design, ultraprecision polishing, and measurement of freeform progressive lenses
- Author
-
Sandy To, L. T. Ho, Ling Bing Kong, Bo Wang, K. T. Lai, and Chi Fai Cheung
- Subjects
Engineering ,Engineering drawing ,business.industry ,medicine ,Polishing ,Injection moulding ,Presbyopia ,Integrated approach ,business ,medicine.disease ,Computing systems ,Manufacturing capability - Abstract
The importance of presbyopia is that it affects 100% of people at their late adulthood and it starts to show up at 40s. The market for high quality progressive lenses is very large. There is a growing need for freeform progressive lenses with a small interval of degree to provide a clear and comfortable intermediate vision for presbyopic patients. Due to the lack of adequate design and manufacturing capability, most of the freeform progressive lenses are designed and imported from overseas at a high price and with long delivery time. This paper presents an integrated approach for supporting design, fabrication and measurement of freeform progressive lenses. A prototype of an integrated system has been developed based on key technologies including an advanced optics design method, computer controlled ultra-precision polishing (CCUP), precision injection moulding, as well as a new freeform surface characterization method. A prototype system has been built and experimental verified successfully through a series of experiments. Successful development of the system will provide an important means for optometry research of freeform progressive lenses.
- Published
- 2012
- Full Text
- View/download PDF
48. Manufacturing Automation, Polymer Composites
- Author
-
Aylin Yenilmez‐Gurkok and Ibrahim N. Tansel
- Subjects
Engineering ,business.industry ,media_common.quotation_subject ,Composite number ,Automation ,Manufacturing engineering ,Manufacturing capability ,Consistency (database systems) ,Machining ,Polymer composites ,Advanced manufacturing ,Quality (business) ,business ,media_common - Abstract
Automation of polymer composite manufacturing would allow better control of part quality and consistency, reduce cost, and improve quality of work environment. In this article, automation of the different stages of the manufacturing process, fully automated procedures, and machining of the composites is discussed. The cost and manufacturing capability limitations are the two main obstacles, which limit use of composite parts in consumer products. Expansion of automated composite manufacturing facilities would eliminate these obstacles, allowing large-scale production of high quality products. Keywords: composite; automation; machining
- Published
- 2012
- Full Text
- View/download PDF
49. Uncooled detector development at Raytheon
- Author
-
M. Lamb, Eli E. Gordon, R. Kraft, T. Yang, Thomas A. Kocian, T. Sessler, Stephen H. Black, and R. Williams
- Subjects
Wafer fabrication ,Engineering ,business.industry ,Tailwind ,Program plan ,Detector ,Product line ,Electrical engineering ,Nanotechnology ,Electronics ,business ,Manufacturing capability - Abstract
At the 2010 meeting of the Defense and Security Symposia Raytheon reported on the status of their efforts to establish a high rate uncooled detector manufacturing capability. At that time we had just finished the transition of the 640 × 480, 25 μm product to our 200 mm wafer fab line at Freescale semiconductor and established an automated packaging and test capability. Over the past year we have continued to build on that foundation. In this paper we will report on this year's progress in completing the transition of our 25 μm product line to Freescale semiconductor. Included will be the 320 × 240 product transition and a summary of SPC and defectivity data from one year's production. Looking beyond 25 μm, we are well along in our transition of the 17 μm product line to Freescale, with test results being available for the 640 × 480. Additionally, we will report on progress / status of the Tailwind program, which is developing a 2048 × 1536, 17 μm uncooled sensor. Data to be reported includes the establishment of subfield stitching at a high rate commercial fab and the development of the detector package and electronics. With 17 μm transitioned to production, Raytheon has started work on the HD LWIR program, which is laying the foundation for the next generation of uncooled detectors by further shrinking the pixel to
- Published
- 2011
- Full Text
- View/download PDF
50. Advanced CdTe Photovoltaic Technology: September 2007 - March 2009
- Author
-
Kurt L. Barth
- Subjects
Engineering ,business.industry ,Semiconductor materials ,Capital equipment ,Photovoltaic system ,Electrical engineering ,Factory ,business ,Activity-based costing ,Solar energy ,Cadmium telluride photovoltaics ,Manufacturing engineering ,Manufacturing capability - Abstract
During the last eighteen months, Abound Solar (formerly AVA Solar) has enjoyed significant success under the SAI program. During this time, a fully automated manufacturing line has been developed, fabricated and commissioned in Longmont, Colorado. The facility is fully integrated, converting glass and semiconductor materials into complete modules beneath its roof. At capacity, a glass panel will enter the factory every 10 seconds and emerge as a completed module two hours later. This facility is currently undergoing trials in preparation for large volume production of 120 x 60 cm thin film CdTe modules. Preceding the development of the large volume manufacturing capability, Abound Solar demonstrated long duration processing with excellent materials utilization for the manufacture of high efficiency 42 cm square modules. Abound Solar prototype modules have been measured with over 9% aperture area efficiency by NREL. Abound Solar demonstrated the ability to produce modules at industry leading low costs to NREL representatives. Costing models show manufacturing costs below $1/Watt and capital equipment costs below $1.50 per watt of annual manufacturing capacity. Under this SAI program, Abound Solar supported a significant research and development program at Colorado State University. The CSU team continues to make progress on device and materials analysis. Modeling for increased device performance and the effects of processing conditions on properties of CdTe PV were investigated.
- Published
- 2011
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.