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1. [Blood and tissue eosinophilia in patient with angioedema caused by inhibitor of angiotensin converting enzyme (ACE)--case report and a view of literature].

Author

Panaszek B, Barg W, Małolepszy J, Kopeć W, Obojski A, Wytrychowski K, Chmielowicz B, Biełous-Wilk A, Rabski M, and Basińska M

Subjects
Aged, Humans, Male, Angioedema chemically induced, Angiotensin-Converting Enzyme Inhibitors adverse effects, Enalapril adverse effects, Eosinophilia blood
Abstract

A case of angioedema caused by enalapril, undiagnosed for 5 years was presented. Enhanced blood and tissue eosinophilia shown in nasal smear was observed. In addition increased activity of coagulation system was shown manifested by enhance of concentration of Hageman factor and cardiolipin antibodies IgM and IgA isotype. The role of coagulation, complement and fibrinolysis systems in pathogenesis of ACE-inhibitors induced angioedema was discussed. The influence of bradykinin on activity of eosinophils was analyzed.

Published
2003

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