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3 results on '"Tuscano G"'

1. Immune Responses to Invasive Group B Streptococcal Disease in Adults

Author

Bonacci S, Fabbrini M, Tuscano G, Bartolini E, Rinaudo Cd, Carol J. Baker, Edwards Ms, Marcia A. Rench, Buffi G, and Margarit I

Subjects
0301 basic medicine, Male, group B Streptococcus, Epidemiology, lcsh:Medicine, Bacteremia, medicine.disease_cause, Immunoglobulin G, immune response, Serology, Immune Response to Invasive Group B Streptococcus Disease in Adults, 0302 clinical medicine, Antibody Specificity, 030212 general & internal medicine, bacteria, media_common, Aged, 80 and over, biology, Streptococcus, Convalescence, Polysaccharides, Bacterial, Middle Aged, Antibodies, Bacterial, Infectious Diseases, Female, Antibody, Microbiology (medical), Adult, media_common.quotation_subject, 030106 microbiology, adult invasive infection, Microbiology, lcsh:Infectious and parasitic diseases, Streptococcus agalactiae, pilus island, 03 medical and health sciences, Antigen, Streptococcal Infections, medicine, Humans, lcsh:RC109-216, Serotyping, Aged, Research, lcsh:R, biochemical phenomena, metabolism, and nutrition, medicine.disease, capsular polysaccharide, Molecular Typing, Immunology, biology.protein
Abstract

Antibodies to capsular polysaccharides and pilus proteins develop in recovering adults., Immunization of nonpregnant adults could help prevent invasive group B Streptococcus (GBS) infections, but adult immune responses have not been investigated. We defined capsular polysaccharide (CPS) and pilus island (PI) surface antigen distribution and expression and immune responses to GBS infection in nonpregnant adults. Prospective surveillance from 7 hospitals in Houston, Texas, USA, identified 102 adults with GBS bacteremia; 43% had skin/soft tissue infection, 16% bacteremia without focus, and 12% osteomyelitis. CPS-specific IgG was determined by ELISA and pilus-specific IgG by multiplex immunoassay. CPS types were Ia (24.5%), Ib (12.7%), II (9.8%), III (16.7%), IV (13.7%), and V (12.7%); 9.8% were nontypeable by serologic methods. Pili, expressed by 89%, were most often PI-2a. CPS and pilus-specific IgG increased during convalescence among patients with strains expressing CPS or PI. All GBS expressed CPS or PI; 79% expressed both. Increased antibodies to CPS and PI during recovery suggests that GBS bacteremia in adults is potentially vaccine preventable.

Published
2016

2. A prospective epidemiological survey of the natural history of chronic leg ischaemia. Evidence of the severity of prognosis and need for large-scale clinical trials

Author

Belgrano, Ea, Nardella, L, Ponzio, E, Nessi, E, Guala, A, Mazzucchetti, S, Graziano, L, Urban, I, Palombo, D, Brustia, P, Calzoni, D, Bellone, M, Altieri, M, Agus, Gb, De Angelis, R, Marrocu, R, Grossi, A, Frigerio, D, Biasi, Gm, Piglionica, Mr, Agrifoglio, G, Costantini, A, Della Vedova MR, Miglierina, L, Lavorato, E, Emanuelli, G, Rossi, R, Flandoli, C, Ponti, Gb, Berra, S, Losapio, Gm, Ambrosi, R, Inzoli, Mr, Lombardi, G, Tarantola, P, Zocca, N, Sforza, M, Russo, R, Tenchini, P, Bruni, T, Fontanili, M, Guidetti, D, Odero, A, Salvini, M, Pedeferri, G, Bordoni, Mc, Visconti, W, Vedovato, E, Bittolo Bon, G, Maffei, L, Marcon, G, Dell'Olivo, I, Gracco, L, Petralia, G, Cordiano, C, Dorucci, V, Pagnan, A, Visona', A, Tonietto, G, E Favretti E, Agresta, Burigo, E, Giansante, C, Fiotti, N, Pamich, G, Santirocco, C, Mozzon, L, Gonano, N, Petrilli, Gl, Puzzo, A, Baldino, G, Podestà, A, Guastini, A, Traversaro, A, Zinicola, N, Baglietto, F, Borgatti, E, Filippini, M, E Ridolfi Coppi G, Ferrari, Tuscano, G, Lonardi, R, Botta, Gc, Banchini, E, Pavarini, E, Delmonte, E, Bucherini, E, Moratti, A, Ieran, M, Bertini, D, Pratesi, C, Corsi, C, Pollastri, M, Marrapodi, E, Vanni, D, Ralli, L, Cecchi, M, Bigalli, A, Del Carratore, G, Mosca, E, Vatteroni, F, Setacci, C, Cao, P, Verzini, F, Mannarino, E, Pasqualini, L, Fedeli, E, Alò, E, Ioannidis, G, Spartera, C, Marino, G, Medori, M, Pola, P, Dal Lago AA, Di Giovanani, V, Colli, R, Maniscalco, G, Bartolo, M, Todini, Ar, Benedetti-Valentini, E, Irace, L, Fiorani, P, Taurino, M, Marcialis, A, Valitutti, P, Vigliotti, G, Regina, G, Fullone, M, Rizzo, S, Rolli, E, Pascali, M, Lucentini, L, Grilli, M, Correra, H, Florena, M, Cassina, I, Notarbartolo, A, Belvedere, M, Andreozzi, Gm, Di Pino, L, Martini, R, Signorelli, S, Romeo, S, Cormaci, Of, Costanzo, C, Grasso, A, Avanzini, F, Bedoni, P, Bertele', V, Colombo, F, Fellin, G, Pangrazzi, J, Roncaglioni, Mc, Samori, G, Tognoni, G, De Gaetano, G, and Garattini, S

Subjects
Epidemiology, Critical leg ischaemia, Peripheral vascular disease
Published
1996

3. A prospective epidemiological survey of the natural history of chronic leg ischaemia. Evidence of the severity of prognosis and need for large-scale clinical trials

Author

Belgrano, Ea, Nardella, L, Ponzio, E, Nessi, E, Guala, A, Mazzucchetti, S, Graziano, L, Urban, I, Palombo, D, Brustia, P, Calzoni, D, Bellone, M, Altieri, M, Agus, Gb, De Angelis, R, Marrocu, R, Grossi, A, Frigerio, D, Biasi, Gm, Piglionica, Mr, Agrifoglio, G, Costantini, A, Della Vedova, Mr, Miglierina, L, Lavorato, E, Emanuelli, G, Rossi, R, Flandoli, C, Ponti, Gb, Berra, S, Losapio, Gm, Ambrosi, R, Inzoli, Mr, Lombardi, G, Tarantola, P, Zocca, N, Sforza, M, Russo, R, Tenchini, P, Bruni, T, Fontanili, M, Guidetti, D, Odero, A, Salvini, M, Pedeferri, G, Bordoni, Mc, Visconti, W, Vedovato, E, Bittolo Bon, G, Maffei, L, Marcon, G, Dell'Olivo, I, Gracco, L, Petralia, G, Cordiano, C, Dorucci, V, Pagnan, A, Visona', A, Tonietto, G, Agresta, E, Favretti, E, Burigo, E, Giansante, C, Fiotti, N, Pamich, G, Santirocco, C, Mozzon, L, Gonano, N, Petrilli, Gl, Puzzo, A, Baldino, G, Podestà, A, Guastini, A, Traversaro, A, Zinicola, N, Baglietto, F, Borgatti, E, Filippini, M, Ferrari, E, Ridolfi, Coppi, G, Tuscano, G, Lonardi, R, Botta, Gc, Banchini, E, Pavarini, E, Delmonte, E, Bucherini, E, Moratti, A, Ieran, M, Bertini, D, Pratesi, C, Corsi, C, Pollastri, M, Marrapodi, E, Vanni, D, Ralli, L, Cecchi, M, Bigalli, A, Del Carratore, G, Mosca, E, Vatteroni, F, Setacci, C, Cao, Piergiorgio, Verzini, Fabio, Mannarino, Elmo, Pasqualini, L, Fedeli, E, Alò, E, Ioannidis, G, Spartera, C, Marino, G, Medori, M, Pola, P, Dal Lago, Aa, Di Giovanani, V, Colli, R, Maniscalco, G, Bartolo, M, Todini, Ar, Benedetti Valentini, E, Irace, L, Fiorani, P, Taurino, M, Marcialis, A, Valitutti, P, Vigliotti, G, Regina, G, Fullone, M, Rizzo, S, Rolli, E., Pascali, M, Lucentini, L, Grilli, M, Correra, H, Florena, M, Cassina, I, Notarbartolo, A, Belvedere, M, Andreozzi, Gm, Di Pino, L, Martini, R, Signorelli, S, Romeo, S, Cormaci, Of, Costanzo, C, Grasso, A, Avanzini, F, Bedoni, P, Bertele', V, Colombo, F, Fellin, G, Pangrazzi, J, Roncaglioni, Mc, Samori, G, Tognoni, G, De Gaetano, G, Garattini, S, and Tognoni, G.

Subjects
Epidemiology, Critical leg ischaemia, Peripheral vascular disease
Published
1996

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