Search

Yuanyuan Duan,1 Lin Ma,2 Carlos Galzote,3 Fan-Qi Kong,1 Chun-Ping Shen2 1Johnson & Johnson Asia Pacific Skin Testing Center, Minhang, Shanghai, People’s Republic of China; 2Department of Dermatology, Beijing Children’s Hospital, Capital Medical University, MOE Key Laboratory of Major Diseases in Children, Beijing, People’s Republic of China; 3Johnson & Johnson International (Singapore) Pte. Ltd., Singapore, SingaporeCorrespondence: Carlos GalzoteJohnson & Johnson International (Singapore) Pte. Ltd., Km 14 Edison Road, Bo. Ibayo, Paranaque City 1700, PhilippinesTel +632 368 8260Fax +632 824 2329Email cgalzote@its.jnj.comIntroduction: Few data are available on the comparison between the effects on infant skin of skin care products and those of water alone.Patients and methods: In this single-center, evaluator-blind, parallel-group pilot study, healthy infants were randomized to near-daily washing for 12 weeks (starting in the summer and finishing in the winter months) with a mild liquid baby wash followed by use of baby lotion (wash+lotion), water followed by baby lotion (water+lotion), or water alone. Clinical and instrumental assessments of skin moisturization and barrier function were made.Results: As expected the skin condition in all groups was affected by the change of the season. The skin of infants in all groups was mildly deteriorated (clinical grading) and with reduced moisture levels and increased barrier function. Instrumental measurements indicated that skin moisture and barrier function were better maintained in the wash+lotion and water+lotion groups than in the water-only group at week 12. Clinical assessment scores increased slightly over 12 weeks in all groups (P