1. Polymicrogyria in a fetus with human parvovirus B19 infection: a case with radiologic-pathologic correlation.
- Author
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Courtier J, Schauer GM, Parer JT, Regenstein AC, Callen PW, and Glenn OA
- Subjects
- Abortion, Induced, Adult, Diagnosis, Differential, Erythema Infectiosum diagnostic imaging, Erythema Infectiosum virology, Female, Humans, Hydrops Fetalis diagnostic imaging, Hydrops Fetalis virology, Malformations of Cortical Development diagnostic imaging, Malformations of Cortical Development virology, Parvovirus B19, Human, Pregnancy, Pregnancy Complications, Infectious diagnostic imaging, Pregnancy Complications, Infectious virology, Erythema Infectiosum diagnosis, Hydrops Fetalis diagnosis, Magnetic Resonance Imaging, Malformations of Cortical Development diagnosis, Pregnancy Complications, Infectious diagnosis, Ultrasonography, Prenatal
- Abstract
We report the prenatal magnetic resonance imaging (MRI) appearance of polymicrogyria with pathologic correlation in a fetus with congenital parvovirus B19 infection. Prenatal ultrasound revealed non-immune hydrops, but detected no fetal brain abnormalities. A subsequent fetal MRI scan performed at 23 weeks' gestation demonstrated bilateral polymicrogyria, which was confirmed at autopsy. To our knowledge, prenatal diagnosis of polymicrogyria in association with congenital parvovirus B19 infection has not been previously described. This case provides further evidence for brain abnormalities resulting from congenital parvovirus B19 infection, and suggests that fetal neuroimaging with MRI would be of value in suspected cases of congenital parvovirus infection., (Copyright © 2012 ISUOG. Published by John Wiley & Sons, Ltd.)
- Published
- 2012
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