1. Esophageal body motility in people with diabetes: Comparison with non-diabetic healthy individuals
- Author
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Carlos Costa Almeida, Mário Amaral Simões, João Xavier Jorge, Edgard Augusto Panão, Cláudia Cardoso Borges, A. Silva, Álvaro Correia Coelho, and Fernando Jorge Delgado
- Subjects
Male ,medicine.medical_specialty ,Manometry ,Endocrinology, Diabetes and Metabolism ,Esophageal body ,Motility ,Gastroenterology ,Esophagus ,Endocrinology ,Reference Values ,Diabetes mellitus ,Internal medicine ,Internal Medicine ,medicine ,Humans ,Esophageal Motility Disorders ,Peristalsis ,Distal esophagus ,Portugal ,business.industry ,General Medicine ,Middle Aged ,medicine.disease ,medicine.anatomical_structure ,Diabetes Mellitus, Type 2 ,Case-Control Studies ,Healthy individuals ,Female ,business ,Non diabetic - Abstract
The aim of this study was to compare esophageal motor characteristics between diabetics and healthy individuals.Esophageal manometry was performed in 34 type 2 diabetics and 32 healthy individuals. Waves were evaluated in the 3 thirds of the esophagus (P1=upper, P2=middle, and P3=distal).In diabetics vs. controls, wave distribution was as follows: peristaltic waves, 83.5 ± 22.2% vs. 96.3 ± 4.4%, p0.002; simultaneous waves, 3.26 ± 5.8% vs. 0.53 ± 1.3%, p0.01; no transmitted waves, 10.62 ± 20.7% vs. 2.75 ± 3.0%, p0.002; and retrograde waves, 2.68 ± 4.0% vs. 0.31 ± 1.1%, p0.03. Wave amplitude was similar between groups. Average upstroke (mmHg/s) in diabetics vs. non-diabetics was P2, 33.8 ± 13.9 vs. 40.2 ± 17.7, p0.03; and P3, 29.8 ± 15.3 vs. 41.3 ± 14.0, p0.002.(1) Simultaneous waves, no transmitted waves, and retrograde esophageal waves were significantly more frequent in diabetics. (2) Average upstroke was significantly lower within the middle and distal esophagus of diabetic individuals. (3) Wave amplitude was similar in both groups.
- Published
- 2012
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