Search

Sideritis L. (Lamiaceae) is represented by 45 species in Flora of Turkey. Sideritis lanata L. (Hairy ironwort) is located in the north-west, west, south-west and central Anatolia. Mountain tea (Sideritis plants) is used as a traditional remedy against common cold and gastrointestinal disorders. Its beneficial properties are attributed to its rich bioactive constituents. In this study, the antioxidant activities of the extracts of Sideritis lanata prepared using different solvents (n-hexane, ethyl acetate, and 70% ethanol) from the aerial parts were determined by DPPH· scavenging effect assay. Also; determined of the antimicrobial activity of S. lanata extracts against 4 bacteria and 5 Candida species. Dried aerial parts of Sideritis were subjected to hydrodistillation and the oil obtained was analyzed by using GC and GC/MS. S. lanata extracts prepared with 70% ethanol was found to have a higher DPPH· scavenging activity (IC50= 0.241 mg/mL) than extracts prepared with other solvents. All extracts showed generally weak inhibitory effects (500-8000 μg/mL, MIC) against bacterial strains. Inhibitory doses against the tested Candida species were determined between 125-4000 μg/mL. The 70% ethanol extract of S. lanata inhibited Candida tropicalis (ATCC 750) (MIC: 125 μg/mL).

In this present study, it was aimed to determine the composition of the essential oil obtained by water distillation from the aerial parts of Origanum acutidens. The oil was analysed by GC-FID and GC/MS. Carvacrol (69.3%), p-cymene (8.3%), y-terpinene (6.3%), β-caryophyllene (2.7%) and borneol (2.2%) were found as main constituents. In addition, headspace-solid phase microextraction using a Polydimethylsiloxane-Divinylbenzene (PDMS/DVB – 65 μm) fiber of O. acutidens was performed and analysed by GC-FID and GC/MS. The main components were identified as: carvacrol (44.0%), p-cymene (25%), ϒ-terpinene (8%), β-caryophyllene (6.1%) and borneol (6.1%), respectively.

WOS: 000520855700007, Apart from being a popular spice, Origanum species is very important taxa as an herbal medicine for their several pharmacological activities. Essential oils of Origanum species bearing phenolic monoterpenoids such as carvacrol and thymol demonstrated strong antimicrobial properties. in the present study hydrodistilled essential oil of endemic species Origanum boissieri Ietswaart were analysed by GC and GC/MS techniques simultaneously. Thirty compounds representing 95.1 % of the total oil were identified. Carvacrol (39%) and p-cymene (32%) were detected as the main components of the oil. Total methanol extract and essential oil of the flowering aerial parts of the plant with the carvacrol and p-cymene were screened for its antibacterial and anticandidal properties by using microdilution broth assay. Bacillus cereus, Bacillus suhtilis, Staphylococcus aureus, Staphlylococcus epiderrnidis and Listeria inortocytogenes were strongly inhibited by the oil between the concentrations of 15,6 - 62.5 mu g/mL. O. boissieri extract and the oil showed moderate effects against all tested Candida strains having MIC values of 125-1000 mu g/mL.

The genus Scutellaria L. (Lamiaceae) is represented in Turkey by 16 species, 1 natural hybrid, 38 taxa, 16 being endemic in Turkey (1,2). Hydrodistilled essential oils of the aerial parts of Scutellaria altissima L. and Scutellaria orientalis L. subsp. pinnatifida Edmondson were analyzed by GC and GC-MS systems, simultaneously. The oil of S. altissima contained β-caryophyllene (34.7 %), caryophyll-5-en-12-al (14.4%), linalool (14.3%) and hexadecanoic acid (7.1%) as main constituents. The oil of S. orientalis L. subsp. pinnatifida was characterized by the occurrence of germacrene D (56.9%), β-caryophyllene (10.5%) and bicyclogermacrene (10.1%) as major components. To the best of our knowledge, this is the first report on the GC and GC/MS determination of the essential oil composition of the S. altissima and S. orientalis subsp. pinnatifida species studied.

WOS: 000424384100004, In the present study, aerial parts of Nepeta cilicica were hydro-distilled for the essential oil. Furthermore, air-dried plant materials were extracted with methanol. According to GC-MS results, 35 compounds were characterized in the oil (totally 92%). Caryophyllene oxide, beta-caryophyllene and spathulenol (28.2, 8.9 and 4.2%) were found as main components of the oil. Sixteen compounds were detected by LC/MS, most of which were caffeoylquinic acid, luteolin and apigenin derivatives, in methanolic extract of the N. cilicica. Apart from DPPH radical scavenging activity, inhibitory effects on bacterial and yeast growth of essential oil and the methanolic extract were evaluated. Twenty-four different pathogenic bacterial and Candida strains were tested by M7-A7 and CLSI M27-A2 protocols respectively. The crude extract showed better inhibitory effects against bacteria strains than the essential oil. Both oil and the extract demonstrated strong inhibition on C. tropicalis at a concentration of 47.0 mu g/mL (MIC).

Flowering aerial parts of Stachvs citrina Boiss. et Heldr. sıtbsp. citrina (Lamiaceae) being endemic for Tıırkev were subjected to hvdrodistili ati on to obtain the essential oil which was further analysed by GC-FID and GC-MS, simultaneously. 36 constituents were determined in the oil, where a-pinene (29.8%) and f-phellandrene (13.6%) w ere identifıed as the maiti components. The anticandidal and antibaeterial effects of the oil were evaluated by ıısing mierodilution method. The oil showed weak inhibitorv effects against the tested bacteria panel (1.25 to 5.0 mg/mL, MIC) whereas the Candida strains were inhibited at lower concentrations of the oil. Especiallv C. glabrata was inhibited at a concentration of0.078 mg/mL of the oil

WOS: 000297013200022, PubMed ID: 22083927, Hydrodistallation of the aerial parts of Nepeta transcaucasica Grossh. (Lamiaceae), collected in Agri, Dogubayazit Province, afforded an essential oil that was characterized by GC and GC/MS analyses. Twenty-seven compounds, representing 97.69% of the total oil composition, were identified, and 4aa,7a,7a beta-nepetalactone (1; 39%), 4aa,7a,7aa-nepetalactone (2; 28%), and germacrene D (3; 15%) constituted the major components. The anticandidal effects of the oil were evaluated against seven Candida strains by using the broth microdilution method. The oil showed good inhibitory effects against C. glabrata and C. tropicalis at minimal inhibitory concentrations (MICs) of 0.09 and 0.375 mg/ml, respectively.

WOS: 000268255900040, …

WOS: 000257300800012, The essential oil obtained by hydrodistillation front three endemic Centaurea species (Asteraceae) in Phalolepis (Cass.) DC. Section; C. wagenitzii Hub.-Mor., C. tossiensis Freyn et Sint. and C. luschaniana Heimerl front Turkey were analyzed by gas chromatography (GC) and gas chromatography/mass spectrometry (GUMS), simultaneously. Main constituents of the oils were found its hexadecanoic acid (25.6%, 50.6% and 40.0%, respectively). Fatty acids and their esters were identified as the main constituent groups of the three species.

WOS: 000246483500021, PubMed ID: 17329038, Composition of the water-distilled oil of the aerial parts of Centaurea aladagensis, endemic in Turkey, was analysed by GC-MS. Hexadecanoic acid (39.3%), caryophyllene oxide (6.6%) and hexahydrofamesyl acetone (4.3%) were found as main constituents in the oil. The oil was tested against 7 human pathogenic microorganisms.

WOS: 000229358400026, …

Stachys lavandulifolia Vahl. subsp. lavandulifolia (Lamiaceae) is widely used in south Anatolia as a herbal tea. It is used for the treatment of gastrointestinal and respiratory disorders. Constituents of the essential oil obtained by hydrodistillation were analyzed both by GC-FID and GC/MS, simultaneously. Thirty-seven compounds representing 98.3% of the oil were characterized. β-Phellandrene (27%), α-pinene (18.5%) and germacrene-D (13%) were found as major components of the oil. Anticandidal, antibacterial and antioxidant properties of the oil and the prepared infusion were evaluated using several methods. The oil exhibited good inhibitory activity on Candida tropicalis (MIC 0.094 mg/mL). Staphylococcus aureus and Salmonella typhimurium growths were also inhibited by the oil at a concentration of 0.375 mg/mL. The prepared infusion of the flowering aerial parts showed weak antimicrobial effects against all the tested microorganisms, but demonstrated a remarkably radical scavenging activity (IC50: 3.9 μg/mL).

Flowering aerial parts of Stachys citrina Boiss. et Heldr. subsp. citrina (Lamiaceae) being endemic for Turkey were subjected to hydrodistillation to obtain the essential oil which was further analysed by GC-FID and GC-MS, simultaneously. 36 constituents were determined in the oil, where a-pinene (29.8%) and ß-phellandrene (13.6%) were identified as the main components. The anticandidal and antibacterial effects of the oil were evaluated by using microdilution method. The oil showed weak inhibitory effects against the tested bacteria panel (1.25 to 5.0 mg/mL, MIC) whereas the Candida strains were inhibited at lower concentrations of the oil. Especially C. glabrata was inhibited at a concentration of 0. 078 mg/mL of the oil.