30 results on '"Erku, Daniel"'
Search Results
2. Socio-demographic correlates of unhealthy lifestyle in Ethiopia: a secondary analysis of a national survey
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Gelaw, Yalemzewod Assefa, Koye, Digsu N., Alene, Kefyalew Addis, Ahmed, Kedir Y., Assefa, Yibeltal, Erku, Daniel Asfaw, Tegegn, Henok Getachew, Tesema, Azeb Gebresilassie, Zeleke, Berihun Megabiaw, and Melaku, Yohannes Adama
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- 2023
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3. Cost-utility analysis of caspofungin and fluconazole for primary treatment of invasive candidiasis and candidemia in Ethiopia
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Gebretekle, Gebremedhin Beedemariam, Fentie, Atalay Mulu, Gebremariam, Girma Tekle, Ali, Eskinder Eshetu, Erku, Daniel Asfaw, Alemayehu, Tinsae, Abebe, Workeabeba, and Sander, Beate
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- 2022
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4. Contraceptive use among HIV-positive and negative women: implication to end unintended pregnancy
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Mersha, Amanual Getnet, Erku, Daniel Asfaw, Belachew, Sewunet Admasu, Ayele, Asnakew Achaw, Gebresillassie, Begashaw Melaku, and Abegaz, Tadesse Melaku
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- 2019
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5. Assessment of community pharmacy professionals’ knowledge and counseling skills achievement towards headache management: a cross-sectional and simulated-client based mixed study
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Netere, Adeladlew Kassie, Erku, Daniel Asfaw, Sendekie, Ashenafi Kibret, Gebreyohannes, Eyob Alemayehu, Muluneh, Niguse Yigzaw, and Belachew, Sewunet Admasu
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- 2018
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6. Assessment of predictors for acute asthma attack in asthmatic patients visiting an Ethiopian hospital: are the potential factors still a threat?
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Belachew, Sewunet Admasu, Erku, Daniel Asfaw, Yimenu, Dawit Kumilachew, and Gebresillassie, Begashaw Melaku
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- 2018
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7. Prevalence and correlates of herbal medicine use among type 2 diabetic patients in Teaching Hospital in Ethiopia: a cross-sectional study
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Mekuria, Abebe Basazn, Belachew, Sewunet Admasu, Tegegn, Henok Getachew, Ali, Dawit Simegnew, Netere, Adeladlew Kassie, Lemlemu, Eskedar, and Erku, Daniel Asfaw
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- 2018
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8. A systematic review of scope and quality of health economic evaluations conducted in Ethiopia.
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Erku, Daniel, Mersha, Amanual G, Ali, Eskinder Eshetu, Gebretekle, Gebremedhin B, Wubishet, Befikadu L, Kassie, Gizat Molla, Mulugeta, Anwar, Mekonnen, Alemayehu B, Eshetie, Tesfahun C, and Scuffham, Paul
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There has been an increased interest in health technology assessment and economic evaluations for health policy in Ethiopia over the last few years. In this systematic review, we examined the scope and quality of healthcare economic evaluation studies in Ethiopia. We searched seven electronic databases (PubMed/MEDLINE, EMBASE, PsycINFO, CINHAL, Econlit, York CRD databases and CEA Tufts) from inception to May 2021 to identify published full health economic evaluations of a health-related intervention or programme in Ethiopia. This was supplemented with forward and backward citation searches of included articles, manual search of key government websites, the Disease Control Priorities-Ethiopia project and WHO-CHOICE programme. The quality of reporting of economic evaluations was assessed using the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) checklist. The extracted data were grouped into subcategories based on the subject of the economic evaluation, organized into tables and reported narratively. This review identified 34 full economic evaluations conducted between 2009 and 2021. Around 14 (41%) of studies focussed on health service delivery, 8 (24%) on pharmaceuticals, vaccines and devices, and 4 (12%) on public-health programmes. The interventions were mostly preventive in nature and focussed on communicable diseases (n = 19; 56%) and maternal and child health (n = 6; 18%). Cost-effectiveness ratios varied widely from cost-saving to more than US $37 313 per life saved depending on the setting, perspectives, types of interventions and disease conditions. While the overall quality of included studies was judged as moderate (meeting 69% of CHEERS checklist), only four out of 27 cost-effectiveness studies characterized heterogeneity. There is a need for building local technical capacity to enhance the design, conduct and reporting of health economic evaluations in Ethiopia. [ABSTRACT FROM AUTHOR]
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- 2022
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9. Tobacco control and prevention efforts in Ethiopia pre- and post-ratification of WHO FCTC: Current challenges and future directions.
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Erku, Daniel Asfaw and Tesfaye, Eyasu Teshome
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SMOKING prevention , *TOBACCO products , *ADVERTISING , *COMMITTEES , *MARKETING , *HEALTH policy , *STRATEGIC planning , *MANUFACTURING industries , *QUALITATIVE research , *TOBACCO laws - Abstract
INTRODUCTION Being the second most populous African country, Ethiopia represents a huge opportunity for the tobacco industry to recruit new smokers. Ethiopia signed the convention to ratify WHO Framework Convention on Tobacco Control (FCTC) in 2004 and ratified in 2014. We reviewed Ethiopia's tobacco control legislative history pre- and post-ratification of the WHO FCTC and evaluated the level of compliance of the National Tobacco Control Directive (NTCD) with the WHO FCTC. METHODS We reviewed Ethiopia's tobacco legislative history, the NCTD, the National Tobacco Control Strategic Plan, and tobacco control related media stories from 2009 to 2018. The level of compliance of NTCD with WHO FCTC was compared and qualitatively analysed. RESULTS NTCD 2015 is Ethiopia's first comprehensive tobacco control legislation, which for the most part is WHO FCTC compliant. The legislation prohibits, among other things, sale of flavoured tobacco products including menthol, sale of tobacco products to a person under the age of 18 years and bans all forms of tobacco advertising, promotion, and sponsorship. Yet, the current legislation allows smoking designated rooms in some prohibited places. Although a multi-sectoral National Tobacco Control Committee and a Strategic Plan were developed as per Article 5 of WHO FCTC, activities pertaining to the protection of such tobacco control policies from vested interests of the tobacco industry (WHO FCTC Article 5.3) are not addressed in NTCD 2015. CONCLUSIONS Major gaps in the NTCD 2015 such as allowing smoking designated rooms should be addressed in order to stop the tobacco industry from using such loopholes to interfere with national tobacco control policies and/or maintain its tobacco market. Moreover, the tobacco control policies and efforts should be institutionalized across various sectors in order to ensure implementation of the NTCD. [ABSTRACT FROM AUTHOR]
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- 2019
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10. Pharmacist-led smoking cessation services in Ethiopia: Knowledge and skills gap analysis.
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Erku, Daniel Asfaw, Hailemeskel, Bisrat, Netere, Adeladlew Kassie, and Belachew, Sewunet Admasu
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ANALYSIS of variance , *CLINICAL competence , *COMMUNITY health workers , *COUNSELING , *DRUG addiction , *HEALTH occupations students , *MEDICAL protocols , *MEDICAL practice , *SCIENTIFIC observation , *PHARMACISTS , *PROFESSIONAL employee training , *PROFESSIONS , *QUESTIONNAIRES , *SMOKING cessation , *T-test (Statistics) , *CROSS-sectional method , *NICOTINE replacement therapy , *EDUCATION , *ATTITUDE (Psychology) - Abstract
INTRODUCTION The present study's objectives were: 1) assess the knowledge and attitude of pharmacists and pharmacy students regarding smoking/smoking cessation, and 2) document the extent of community pharmacists' involvement in the provision of smoking cessation services in Ethiopia. METHODS This study used cross-sectional and direct observation methods. A series of questionnaires were administered to final-year pharmacy students and practising pharmacists. Two scenarios simulating tobacco use in pregnancy and cardiovascular patients were selected and played by two well-trained simulated patients (SPs). Findings were analysed and presented using mean total scores, analysis of variances and independent sample t-test. RESULTS A total of 410 participants (213 out of 238 pharmacy students, response rate 89.5%; 197 out of 361 pharmacists, response rate 54.6%) completed the survey. Both pharmacy students and practising pharmacists had positive attitudes towards smoking cessation, and both groups had similar mean knowledge scores. A total of 80 simulated visits were conducted. Recipients of training on smoking cessation had significantly higher mean knowledge and attitude scores compared with those who did not receive such training. The majority of the pharmacists demonstrated poor in history-taking practice, and seldom assessed the patients' nicotine dependence level. Nicotine replacement therapies (NRTs) were supplied in only 10 of the visits and suggested, but not dispensed, in 35 of the visits. On the other hand, pharmacists in 59 visits counselled patients to visit addiction specialists and physicians. CONCLUSIONS The present study revealed the presence of significant clinical knowledge gaps and inadequate skills among pharmacists regarding smoking cessation services. Educating pharmacists about smoking cessation support as part of their continuous professional development and providing a hands-on customised educational intervention, such as practice guidelines in the form of an Ask-Advise-Refer approach, about smoking cessation will be useful. [ABSTRACT FROM AUTHOR]
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- 2019
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11. Evaluating patients’, physicians’ and pharmacy professionals’ perception and concern regarding generic medicines in Gondar town, northwest Ethiopia: A multi-stakeholder, cross-sectional survey.
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Gebresillassie, Begashaw Melaku, Belachew, Sewunet Admasu, Tefera, Yonas Getaye, Abebe, Tamrat Befekadu, Mekuria, Abebe Basazn, Haile, Kaleab Taye, and Erku, Daniel Asfaw
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PHYSICIANS ,PHARMACY ,CROSS-sectional method ,MEDICAL statistics ,PHARMACISTS - Abstract
Background: Generic medicine prescribing has become common practice in many countries. However, data regarding the perceptions of stakeholders (patients, prescribers and dispensers) regarding generic medicines in Ethiopia is scarce. The present survey aimed to investigate the perception of patients, physicians and pharmacy professionals regarding generic medicines in Ethiopia. Methods: A quantitative cross-sectional survey was conducted in Gondar town, Northwest Ethiopia between January 1 and February 1, 2017. The questionnaire, comprised of 5-point Likert scale items on perception and concerns regarding generic medicine, was administered to patients, physicians and pharmacy professionals working in the community drug retail outlets. Frequencies, percentages, and median were calculated using Statistical Package for the Social Sciences (SPSS) software version 21.0 for Windows to describe different variables. Results: The survey was completed by 612 participants. More than half of patients, 56% (n = 219) knew about the term brand and generic medicines and 38.7% (n = 151) of patients agreed/strongly agreed that brand medicines are more effective. Nearly half, 47% (n = 184) of patients agreed that they should have the option of choosing between generic and brand medicines and 61.4% (n = 240) of patients believed that cost should be considered before a medicineis prescribed. The majority of physicians 70.6% (n = 101) indicated a very low generic medicine prescription rate. 56% (n = 130) of physicians and 87.2% (n = 68) of pharmacy professionals agreed that they need a standard guideline to both prescribers and pharmacists on brand substitution process. Furthermore, 39.9% (n = 57) of the physicians and 87.2% (n = 68) of pharmacy professionals agreed that drug advertisements by the manufacturers would influence their prescribing/dispensing practice. Conclusions: Overall, our findings demonstrate a knowledge gap among patients towards the perception of generics, perceiving generics are less effective and inferior in quality compared to their branded equivalents. The majority of physicians reported a very low generic medicine prescribing rate and the majority pharmacy professionals’ dispensing practice was influenced by drug advertisements. Hence, a customized educational program should be developed and implemented to patients, prescribers and dispensers so as to boost the acceptability of generic medicines and increase generic prescribing and/or substitution. [ABSTRACT FROM AUTHOR]
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- 2018
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12. Management of minor ailments in a community pharmacy setting: Findings from simulated visits and qualitative study in Gondar town, Ethiopia.
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Ayele, Asnakew Achaw, Mekuria, Abebe Basazn, Tegegn, Henok Getachew, Gebresillassie, Begashaw Melaku, Mekonnen, Alemayehu Birhane, and Erku, Daniel Asfaw
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PHARMACISTS ,DISEASE management ,QUALITATIVE research ,COMPUTER simulation ,HISTORY of medicine - Abstract
Community pharmacy professionals are being widely accepted as sources of treatment and advice for managing minor ailments, largely owing to their location at the heart of the community. The aim of the present study was, therefore, to document the involvement of community pharmacy professionals in the management of minor ailments and perceived barriers that limit their provision of such services. Simulated patient (SP) visits combined with a qualitative study using in-depth interviews was conducted among community pharmacy professionals in Gondar town, Northwest Ethiopia. Scenarios of three different minor ailments (uncomplicated upper respiratory tract infection, back pain and acute diarrhea) were selected and results were reported as percentages. Pharmacy professionals were also interviewed about the barriers in the management of minor ailments. Out of 66 simulated visits, 61 cases (92.4%) provided one or more medications to the SPs. Pharmacy professionals in 16 visits asked SPs information on details of symptoms and past medical and medication history. Ibuprofen alone or in combination with paracetamol was the most commonly dispensed analgesics for back pain. Oral rehydration fluid (ORS) with zinc was the most frequently dispensed medication (33.3%) for the management of acute diarrhea followed by mebendazole (23.9%). Moreover, amoxicillin-clavulanic acid capsule (35%) followed by Amoxicillin (25%) were the most commonly dispensed antibiotics for uncomplicated upper respiratory tract infection. Lack of clinical training and poor community awareness towards the role of community pharmacists in the management of minor ailments were the main barriers for the provision of minor ailment management by community pharmacy professionals. Overall, community pharmacists provided inadequate therapy for the simulated minor ailments. Lack of access to clinical training and poor community awareness were the most commonly cited barriers for providing such services. So as to improve community pharmacists’ involvement in managing minor ailments and optimize the contribution of pharmacists, interventions should focus on overcoming the identified barriers. [ABSTRACT FROM AUTHOR]
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- 2018
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13. Complementary and alternative medicine use among elderly patients living with chronic diseases in a teaching hospital in Ethiopia.
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Ayele, Asnakew Achaw, Tegegn, Henok Getachew, Haile, Kaleab Taye, Belachew, Sewunet Admasu, Mersha, Amanual Getnet, and Erku, Daniel Asfaw
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Background: The use of complementary and alternative medicine (CAM) among patients with chronic diseases has grown rapidly worldwide. Yet, little has been known about CAM use by elderly patients with chronic diseases in Ethiopia. This study aimed at assessing the prevalence and reasons for CAM utilization among elderly patients living with chronic diseases in Ethiopia.Methods: An institution-based quantitative cross-sectional survey was conducted among elderly patients with chronic disease attending outpatient ambulatory clinics of University of Gondar referral and teaching hospital (UoGRTH). An interviewer-administered and semi-structured questionnaire were utilized to collect the data.Result: Of the total respondents, 240 (74%) reported the use of CAM, with herbal medicine and spiritual healing being the most commonly utilized CAM modalities (50.4% and 40.8% respectively). Dissatisfaction with conventional therapy (40.8%) and belief in the effectiveness of CAM (30.8%) are the most commonly cited reasons for the use of CAM therapies. Rural residency, higher educational status, higher average monthly income and presence of co-morbidity were positively associated with the use of CAM.Conclusion: This survey revealed a higher rate of CAM use among elderly patients with chronic diseases, along with a very low rate of disclosing their use to their health care providers. Special attention should be given for these patient population due to the potentially harmful interaction of different herbal remedies with the prescribed medications, thereby predisposing the patient to untoward adverse effects and compromised overall health outcome. [ABSTRACT FROM AUTHOR]- Published
- 2017
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14. Traditional herbal medicine use among people living with HIV/AIDS in Gondar, Ethiopia: Do their health care providers know?
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Haile, Kaleab Taye, Ayele, Asnakew Achaw, Mekuria, Abebe Basazn, Demeke, Chilot Abiyu, Gebresillassie, Begashaw Melaku, and Erku, Daniel Asfaw
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Background: People living with HIV/AIDS (PLWHA) are increasingly using herbal remedies due to the chronic nature of the disease, the complexities of treatment modalities and the difficulty in adhering to the therapeutic regimens. Yet, research on herbal medicine use in this patient population is scarce in Ethiopia. The present study aimed at investigating the prevalence and factors associated with the use of traditional herbal medicine among PLWHA in Gondar, Ethiopia.Methods: A cross sectional survey was conducted on 360 PLWHA attending the outpatient clinic of University of Gondar referral and teaching hospital from September 1 to 30, 2016. A questionnaire about the socio-demographic, disease characteristics as well as traditional herbal medicine use was filled by the respondents. Descriptive statistics, univariate and multivariate logistic regression analyses were performed to determine prevalence and correlates of herbal medicine use.Results: Out of 360 respondents, 255 (70.8%) used traditional herbal medicine. The most common herbal preparations used by PLWHA were Ginger (Zingiber officinale) (47%), Garlic (Allium sativum L.) (40.8%) and Moringa (Moringa stenopetala) (31.4%). Majority of herbal medicine users rarely disclose their use of herbal medicines to their health care providers (61.2%). Only lower educational status was found to be strong predictors of herbal medicine use in the multivariate logistic regression.Conclusions: The use of herbal medicine among PLWHA is a routine practice and associated with a lower educational status. Patients also rarely disclose their use of herbal medicines to their health care providers. From the stand point of high prevalence and low disclosure rate, health care providers should often consult patients regarding herbal medicine use. [ABSTRACT FROM AUTHOR]- Published
- 2017
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15. Competence in metered dose inhaler technique among community pharmacy professionals in Gondar town, Northwest Ethiopia: Knowledge and skill gap analysis.
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Belachew, Sewunet Admasu, Tilahun, Fasil, Ketsela, Tirsit, Achaw Ayele, Asnakew, Kassie Netere, Adeladlew, Getnet Mersha, Amanual, Befekadu Abebe, Tamrat, Melaku Gebresillassie, Begashaw, Getachew Tegegn, Henok, and Asfaw Erku, Daniel
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METERED-dose inhalers ,INHALERS ,DRUG side effects ,PHARMACISTS ,MEDICAL personnel - Abstract
Background: When compared to systemic administration, if used correctly inhalers deliver a smaller enough percent of the drug right to the site of action in the lungs, with a faster onset of effect and with reduced systemic availability that minimizes adverse effects. However, the health professionals' and patients' use of metered dose inhaler is poor. Objective: This study was aimed to explore community pharmacy professionals' (pharmacists' and druggists') competency on metered dose inhaler (MDI) technique. Method: A cross sectional study was employed on pharmacy professionals working in community drug retail outlets in Gondar town, northwest Ethiopia from March to May 2017. Evaluation tool was originally taken and adapted from the National Asthma Education and Prevention Programmes of America (NAEPP) step criteria for the demonstration of a metered dose inhaler to score the knowledge/proficiency of using the inhaler. Result: Among 70 community pharmacy professionals approached, 62 (32 pharmacists and 30 druggists/Pharmacy technicians) completed the survey with a response rate of 85.6%. Only three (4.8%) respondents were competent by demonstrating the vital steps correctly. Overall, only 13 participants got score seven or above, but most of them had missed the essential steps which included steps 1, 2, 5, 6, 7 or 8. There was a significant difference (P = 0.015) in competency of demonstrating adequate inhalational technique among respondents who took training on basic inhalational techniques and who did not. Conclusion: This study shown that, community pharmacy professionals' competency of MDI technique was very poor. So as to better incorporate community pharmacies into future asthma illness management and optimize the contribution of pharmacists, interventions would emphasis to improve the total competence of community pharmacy professionals through establishing and providing regular educational programs. [ABSTRACT FROM AUTHOR]
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- 2017
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16. Inappropriate use of antibiotics among communities of Gondar town, Ethiopia: a threat to the development of antimicrobial resistance.
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Erku, Daniel Asfaw, Mekuria, Abebe Basazn, and Belachew, Sewunet Admasu
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ANTIBIOTICS , *ANTI-infective agents , *DRUG resistance - Abstract
Background: The emergence of antimicrobial resistance, the main cause of morbidity and mortality from otherwise treatable infections, is largely attributed to the inappropriate use of antimicrobials. However, data on the extent of inappropriate use of antibiotics in the community is scarce in Ethiopia. The aim of present study is to document the extent of inappropriate use of antibiotics and its associated factors among the communities of Gondar, Northwest Ethiopia. Methods: A community based cross-sectional survey was conducted on a total of 650 participants in Gondar town, northwest Ethiopia from December 1, 2016 to January 30, 2017. Descriptive statistics, univariate and multivariate logistic regression analysis were also performed to express different variables and to examine factors associated with inappropriate use of antibiotics. Results: According to the finding of our study, 315 (48.5%) of the participants took antibiotics in the past 1 year, of which 115 (35.9%) of them used inappropriately. Amoxicillin (72%) was the most commonly utilized antibiotics and respiratory tract infection (40.9%) was the most common disease condition to which antibiotics had been sought. About 36.8% of the respondents got antibiotics from community drug retail outlets without a prescription and 67.9% of respondents had discontinued the use of antibiotics once their symptoms subside. Low educational status (AOR = 5.01, 95% CI = 2.62--9.34), being employed (AOR = 2.12, 95% CI = 1.81--7.29) and unsatisfied with health care services provided (AOR = 5.41, 95% CI = 2.71-14.21) were found to be strong predictors of inappropriate use of antibiotics use among the community. Conclusion: Inappropriate use of antibiotics was found to be considerably high in the communities of Gondar, northwest Ethiopia. Taking into consideration the heightened importance of comprehensive knowledge in the rational use of antibiotics, different stakeholders working in the public health sectors should provide a comprehensive and customized education to the public so as to improve their knowledge about antibiotics. It is also essential to adopt a strong and explicit line of actions towards the accessibility of antibiotics without a valid prescription in community medicine retail outlets. [ABSTRACT FROM AUTHOR]
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- 2017
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17. Involvement of community pharmacists in public health priorities: A multi-center descriptive survey in Ethiopia.
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Erku, Daniel Asfaw and Mersha, Amanual Getnet
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PUBLIC health research , *PHARMACISTS , *QUESTIONNAIRES , *SMOKING cessation - Abstract
Located in the heart of the community and widely distributed geographically, community pharmacies provide a platform for a more proactive involvement in public health services. So far, little information has been gathered in Ethiopia on community pharmacists’ level of involvement in public health services. The aim of the present study was, therefore, to document the level of involvement of community pharmacy professionals in the provision of public health services and the barriers to such involvement. This study employed a self-administered questionnaire based survey, which asked participants to indicate their frequency and level of involvement in providing public health services and their perceived barriers in providing such services. Surveys were undertaken from May to July, 2016 with 472 community pharmacy professionals working in community pharmacies in six cities of Amhara regional state of Ethiopia: Debre Markos, Gondar, Dessie, Bahir Dar, Woldya and Debre Birhan. Among 472 community pharmacy professionals approached, 412 (233 pharmacists and 179 pharmacy technicians) completed the survey with a response rate of 87.3%. Most respondents reported as being either “not at all involved” or “little involved” in counselling on smoking cessation (79.3%), and screening for hypertension (86.9%), diabetes (89.5%), and dyslipidemia (88.9%). On the other hand, they reported a higher level of involvement in the management and screening of infectious diseases (72.8%) and counseling with partners when initiating treatment for sexually transmitted diseases (68.9%). Lack of knowledge or clinical skills and lack of personnel or resources were the most commonly reported barrier for expanding such services. This survey revealed a low level of involvement of community pharmacists in public health services. In order to better integrate community pharmacies into future public health programs and optimize the contribution of community pharmacy professionals, interventions should focus on overcoming the identified barriers. [ABSTRACT FROM AUTHOR]
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- 2017
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18. The role of community pharmacists in patient counseling and health education: a survey of their knowledge and level of involvement in relation to type 2 diabetes mellitus.
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Erku, Daniel Asfaw, Belachew, Sewunet Admasu, Mekuria, Abebe Basazn, Haile, Kaleab Taye, Gebresillassie, Begashaw Melaku, Tegegn, Henok Getachew, and Ayele, Asnakew Achaw
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PEOPLE with diabetes ,PHARMACISTS ,PATIENT education - Abstract
Purpose: The present study aimed at evaluating the knowledge and level of involvement of community pharmacists in the provision of patient counseling and health education services for patients with DM and perceived barriers that limit the delivery of such services. Materials and methods: A self-administered questionnaire based-survey was undertaken from January to March, 2017 with 412 pharmacists working in community pharmacies in six cities of Amhara regional state of Ethiopia: Debre Markos, Gondar, Dessie, Bahir Dar, Woldya, and Debre Birhan. Descriptive statistics, ANOVA, and Student's t-test were employed to examine different variables. Results: Community pharmacists were found to have poor knowledge and low level of involvement, with an overall mean score of 11.54 and 2.06, respectively. A significant number of community pharmacists never practiced promoting smoking cessation (45.2%), counseling on good foot care techniques (33.7%), and counseling on the potential impact of over--the-counter and herbal drugs on DM management (34%). On the other hand, describing the right time to administer antidiabetic medications (46%) and counseling on suitable administration, handling, and storage of insulin (33.7%) were done more frequently. The main reported barriers to the delivery of these services were lack of knowledge or clinical skills, lack of access to additional training programs, and lack of personnel or resources. Conclusion: The present study revealed a poor knowledge and low level of involvement in counseling and health education services for patients with DM. Lack of knowledge or clinical skills was the most commonly reported barrier for providing such services. In order to better integrate community pharmacies into future public health programs and optimize the contribution of pharmacists, interventions should focus on overcoming the identified barriers. [ABSTRACT FROM AUTHOR]
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- 2017
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19. The impact of pharmacist-led medication therapy management on medication adherence in patients with type 2 diabetes mellitus: a randomized controlled study.
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ERKU, Daniel A., AYELE, Asnakew A., MEKURIA, Abebe B., BELACHEW, Sewunet A., HAILEMESKEL, Bisrat, and TEGEGN, Henok G.
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CLINICAL drug trials ,ANALYSIS of variance ,LONGITUDINAL method ,MEDICAL care ,TYPE 2 diabetes ,PATIENT compliance ,PATIENTS ,PHARMACISTS ,PROBABILITY theory ,RANDOMIZED controlled trials ,REPEATED measures design ,CASE-control method ,MEDICATION therapy management ,INDIVIDUALIZED medicine - Abstract
Background: Poor adherence to antidiabetic medications leads to a higher rate of hospital admissions and adverse health outcomes in type 2 diabetes mellitus patients. Objective: This study aims to evaluate whether a pharmacist-led medication therapy management, compared to the usual care, could enhance medication adherence and reduce hospital admission in patients with type 2 diabetes mellitus. Methods: A prospective randomized controlled study was conducted in patients with type 2 diabetes mellitus from February 1 to July 30, 2016. Patients in the control group (n=65) received the usual care while patients in the intervention group (n=62) received a personalized pharmacotherapeutic care plan and diabetes education. The two groups were compared by repeated measure ANOVA at 3 and 6‐months with medication adherence (using Morisky medication adherence scale) and number of hospital admissions as the main outcome variables. Results: A total of 127 patients were included in the study. A marked and statistically significant increase in medication adherence from baseline to 3 and 6 months were noted in the intervention group (increased from 9.2% at baseline to 61% at 6 month) compared with the control group (increased from 13.2% at baseline (to 30.2% at 6 month; p-value<0.01). Furthermore, at the 6-month follow-up, only 23 patients in MTM group with poorly controlled blood glucose levels resulted in hospital admissions compared to 48 patients in non-MTM group, resulting in a 52.1% fewer hospital admissions (p< 0.001). Conclusions: The findings of this study implied that pharmacist-led medication therapy management might improve medication adherence and reduce number of hospitalizations in patients with type 2 diabetes mellitus. Hence, policies and guidelines should be in place in order for clinical pharmacists to fully engage in patient care and improve the medication therapy outcomes. [ABSTRACT FROM AUTHOR]
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- 2017
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20. Community pharmacists’ interest in and attitude to pharmacy practice research in Ethiopia: A cross-sectional study.
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Bhagavathula, Akshaya Srikanth, Gebreyohannes, Eyob Alemayehu, Gebresillassie, Begashaw Melaku, Erku, Daniel Asfaw, Negesse, Chernet Tafere, and Belay, Yared Belete
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PHARMACISTS ,PHARMACEUTICAL industry ,MEDICAL practice ,MULTIVARIATE analysis ,CROSS-sectional method - Abstract
Pharmacy practice-research became an important component in the pharmacy practice. However, limited studies were conducted in sub-Saharan Africa to understand the pharmacists’ interest and attitude towards pharmacy practice-research. We aimed to assess the community pharmacists’ interest and attitude towards pharmacy practice-research in Ethiopia. A cross-sectional survey was conducted among community pharmacists in eight major cities in Ethiopia. A validated 25-item self-administered questionnaire covering interest and attitude related to pharmacy practice-research was distributed. Responses were analysed using descriptive and inferential statistics. A total of 389 community pharmacists responded to the survey (response rate- 88.4%). Most of community pharmacists showed a high level of interest and positive attitude in being involved in all aspects of pharmacy practice-research. The median summary score for interest and attitude were 38 (IQR 20–40) (range possible 10–50) and 30 (IQR 18–39), respectively. Sixty-seven percent of the respondents thought about being involved in research, felt research is important for their career (57.6%), confident to conduct the research (56.2%), and agreed that research is a part of pharmacy practice (48.5%). However, only forty-six percent agreed that they underwent research training. A multivariate analysis showed that females were more interested in pharmacy practice research than males [AOR: 1.50, 95% CI: 0.99–2.27; p<0.05]. Community pharmacists showed high interest towards several areas of research competencies and demonstrated positive attitude towards pharmacy practice-research. Our findings suggest that providing research training to community pharmacists may contribute in undertaking research activities and build the research capacity in Ethiopia. [ABSTRACT FROM AUTHOR]
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- 2017
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21. Off-label drug use in hospitalized children: a prospective observational study at Gondar University Referral Hospital, Northwestern Ethiopia.
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Tefera, Yonas G., Gebresillassie, Begashaw M., Mekuria, Abebe B., Abebe, Tamrat B., Erku, Daniel A., Seid, Nurahmed, and Beshir, Habiba B.
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OFF-label use (Drugs) ,CHILDREN'S health ,CROSS-sectional method ,REGRESSION analysis ,SOCIAL history - Abstract
Most of the medications which are currently used for the treatment of childhood diseases are either not licensed or being prescribed outside the terms of the product license (off-label prescribing). This study aimed at determining the extent of unlicensed and off-label drug uses and associated factors in children hospitalized in Gondar University Referral Hospital, Northwest Ethiopia . An institution-based prospective cross-sectional study was employed from April 15 to July 15, 2016. A total of 243 pediatric patients admitted to Gondar university referral hospital were included in the study using simple random sampling method. Data were collected using structured questionnaire, and the data collected were entered and analyzed using Statistical Packages for Social Sciences ( SPSS) version 20. From the total of 800 drugs prescribed, 607 (75.8%) were off-label. Off-label medicine use was frequently observed in antimicrobials (60.6%) followed by central nervous system drugs (14.3%). The extent off-label prescribing was highest in age group of 6-13 years (30%). Inappropriate dosing and frequency (42.3%) were the most common reason for off-label medicine use. Having other variables controlled, age group and undergoing surgical procedure remained to be significant predictors of off-label prescribing in the multivariate regression analysis. Implementing evidence-based approach in prescribing by generating more quality literatures on the safety profile and effectiveness of off-label would improve the injudicious use of drugs in pediatric population. [ABSTRACT FROM AUTHOR]
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- 2017
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22. Prevalence and associated factors of herbal medicine use among pregnant women on antenatal care follow-up at University of Gondar referral and teaching hospital, Ethiopia: a cross-sectional study.
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Mekuria, Abebe Basazn, Erku, Daniel Asfaw, Gebresillassie, Begashaw Melaku, Birru, Eshetie Melese, Tizazu, Balem, and Ahmedin, Alima
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HERBAL medicine ,ACADEMIC medical centers ,INTERVIEWING ,MATERNAL health services ,MEDICAL referrals ,PRENATAL care ,QUESTIONNAIRES ,STATISTICS ,TIME ,LOGISTIC regression analysis ,CROSS-sectional method ,DATA analysis software ,DESCRIPTIVE statistics ,ODDS ratio - Abstract
Background: Improving maternal and child health is one of the public health priorities in several African countries including Ethiopia. However, research on herbal medicine use during pregnancy is scarce in Ethiopia. The present study aimed at assessing the prevalence and correlates of herbal medicine use among pregnant women on antenatal care (ANC) follow-up at Gondar university referral hospital, Ethiopia Methods: An institutional-based cross sectional study was conducted on 364 pregnant women attending ANC clinic from March to May 2016 at University of Gondar referral and teaching hospital, northwest Ethiopia. Data on socio-demography, pregnancy related information as well as herbal medicine use was collected through an interviewer-administered questionnaire. Descriptive statistics, univariate and multivariate logistic regression analysis were performed to determine prevalence and associated factors of herbal medicine use. Results: From 364 respondents, 48.6% used herbal medicine during current pregnancy. ginger (40.7%) and garlic (19%) were the two most commonly used herbs in pregnancy. Common cold (66%) and inflammation (31.6%) were the most common reasons for herbal use. Majority of herbal medicine users (89.8%) had not consulted their doctors about their herbal medicine use. Rural residency (Adjusted odds ratio (AOR): 3.15, Confidence interval (CI): 1.17-6.14), illiteracy (AOR: 4.05, CI: 2.47-6.62) and average monthly income less than 100 USD (AOR: 3.08CI: 1.221-7.77) were found to be strong predictors of herbal medicine use. Conclusions: The use of herbal medicine during pregnancy is a common practice and associated with residency, level of education and average monthly income. From the stand point of high prevalence and low disclosure rate, the health care providers should often consult pregnant women regarding herbal medicine use. [ABSTRACT FROM AUTHOR]
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- 2017
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23. Self-reported and actual involvement of community pharmacists in patient counseling: a cross-sectional and simulated patient study in Gondar, Ethiopia.
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SURUR, Abdrrahman S., GETACHEW, Eyob, TERESSA, Ebsa, HAILEMESKEL, Bisrat, GETAW, Nurahmed S., and ERKU, Daniel A.
- Abstract
Background: Community pharmacists play a crucial role in reducing medication related health problems and improving the patient’s overall wellbeing. Evidence suggests that community pharmacist led counseling services result in a better clinical and self-reported outcome, including a higher level of satisfaction and quality of life. Objective: This study aims to document self-reported and actual levels of community pharmacists’ involvement in the provision of patient counseling and barriers that limit their involvement in such services. Methods: Simulated patient visits and a cross-sectional survey of community pharmacists were employed in Gondar town, Ethiopia between March 15 and May 15, 2016 to observe actual counseling practices and to assess their reported counseling practices respectively. Four different scenarios were developed for the simulated patient visit. A well designed questionnaire and an assessment form were used for the survey and simulated patient visit. Results: In the cross-sectional survey, 84 pharmacists were approached and 78 agreed to participate (92.8 % response rate). Of the respondents, 96.1% agreed/strongly agreed that patient counseling is important and 69.3% strongly agreed that patient counseling should be a professional duty. The most frequent information provided to patients were dosing schedule of drugs, how to take medication, and drug-food interaction. Majority of community pharmacists either strongly agreed (42.1%) or agreed (51.3%) that patients are comfortable towards their counseling practice. A total of 48 simulated visits were conducted and a medicine was dispensed in all visits. In all four scenarios, dosage schedule (100%), how to take medication (97.6%) and drug-food interaction (69.1%) were the most common type of information provided while what to do when dose is missed (100%), contraindication (95.2%) and the importance of compliance or adherence (92.9%) were the most commonly ignored types of information. Conclusions: The present study emphasizes the existing gap in self-reported and actual counseling practices by community pharmacist in Gondar town, Ethiopia. Hence, the ministry of health, local health policy makers and other stakeholders should collaborate to design interventions to improve community pharmacists’ dispensing and counseling practice. [ABSTRACT FROM AUTHOR]
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- 2017
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24. Pattern of chemotherapy-related adverse effects among adult cancer patients treated at Gondar university referral hospital, Ethiopia: a crosssectional study.
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Belachew, Sewunet Admasu, Erku, Daniel Asfaw, Mekuria, Abebe Basazn, and Gebresillassie, Begashaw Melaku
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CANCER chemotherapy ,DRUG side effects ,CANCER patients ,DISEASES in adults ,PUBLIC health ,THERAPEUTICS - Abstract
Background: Adverse drug reactions (ADRs) are a global problem and constitute a major clinical problem in terms of human suffering. The high toxicity and narrow therapeutic index of chemotherapeutic agents makes oncology pharmacovigilance essential. The objective of the present study was to assess the pattern of ADRs occurring in cancer patients treated with chemotherapy in a tertiary care teaching hospital in Ethiopia. Methods: A cross-sectional study over a 2-year period from September 2013 to August 2015 was conducted on cancer patients undergoing chemotherapy at Gondar University Referral Hospital Oncology Center. Data were collected directly from patients and their medical case files. The reported ADRs were assessed for causality using the World Health Organization's causality assessment scale and Naranjo's algorithm. The severities of the reported reactions were also assessed using National Cancer Institute Common Terminology CTCAE version 4.0. The Pearson's chi-square test was employed to examine the association between two categorical variables. Results: A total of 815 ADRs were identified per 203 patients included in the study. The most commonly occurring ADRs were nausea and vomiting (18.9%), infections (16.7%), neutropenia (14.7%), fever and/or chills (11.3%), and anemia (9.3%). Platinum compounds (31.4%) were the most common group of drugs causing ADRs. Of the reported ADRs, 65.8% were grades 3-4 (severe level), 29.9% were grades 1-2 (mild level), and 4.3% were grade 5 (toxic level). Significant association was found between age, number of chemotherapeutic agents, as well as dose of chemotherapy with the occurrence of grades 3-5 toxicity. Conclusion: The high incidence of chemotherapy-related ADRs among cancer patients is of concern. Setting up an effective ADR monitoring and reporting system (onco-pharmacovigilance) and creating awareness among health care professionals regarding the importance of ADR reporting may help prevent the problem. [ABSTRACT FROM AUTHOR]
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- 2016
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25. Recreational Use of Phosphodiesterase 5 Inhibitors and Its Associated Factors among Undergraduate Male Students in an Ethiopian University: A Cross-Sectional Study.
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Gebreyohannes, Eyob Alemayehu, Bhagavathula, Akshaya Srikanth, Gebresillassie, Begashaw Melaku, Tefera, Yonas Getaye, Belachew, Sewunet Admasu, and Erku, Daniel Asfaw
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PHOSPHODIESTERASE-5 inhibitors ,DRUGS of abuse ,SEXUAL partners ,IMPOTENCE ,UNDERGRADUATES ,DISEASE prevalence ,CROSS-sectional method ,DISEASES - Abstract
Purpose: To assess the prevalence of phosphodiesterase 5 (PDE5) inhibitor use and associated factors among University of Gondar undergraduate students. Materials and Methods: An institution-based, cross-sectional study, using a survey questionnaire, was conducted from October to December 2015 to assess PDE5 inhibitor use and associated factors among male students at the University of Gondar. A Self-Esteem and Relationship questionnaire (14 items), an International Index of Erectile Function questionnaire (15 items) and a questionnaire on PDE5 inhibitor use (14 items) were included in the survey. Results: Across all respondents (age, 21.9±1.88 years), more than half (55.7%, n=233) had heard about PDE5 inhibitors, but only 23 men (5.5%) reported trying a PDE5 inhibitor drug at least once. Older students were more likely to use PDE5 inhibitors compared to younger students (adjusted odds ratio [AOR], 1.40; 95% confidence interval [CI], 1.109∼1.768). Those students who were smokers were 5.15 times more likely to use PDE5 inhibitors as compared to their non-smoking counterparts (AOR, 5.15; 95% CI, 2.096∼12.687). In addition, multivariate logistic regression showed that being in a relationship, alcohol use, greater number of cigarettes smoked per day, and more sexual partners were significantly associated with PDE5 inhibitor use. Conclusions: The prevalence of PDE5 inhibitor use among undergraduate students was 5.5%. Cigarette smoking and other substance use, older age, and greater number of sexual partners were significantly associated factors for PDE5 inhibitor use. These findings suggest that restricting access to PDE5 inhibitor drugs is essential to curtailing misuse among university students. [ABSTRACT FROM AUTHOR]
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- 2016
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26. Expectation and satisfaction of HIV/AIDS patients toward the pharmaceutical care provided at Gondar University Referral Hospital, northwestern Ethiopia: a cross-sectional study.
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Abebe, Tamrat Befekadu, Gebresillassie, Begashaw Melaku, Erku, Daniel Asfaw, Haile, Kaleab Taye, and Mekuria, Abebe Basazn
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AIDS patients ,PATIENT satisfaction ,PHARMACEUTICAL services ,PATIENT compliance ,MEDICAL care ,SURVEYS - Abstract
Purpose: Measurements of patient satisfaction help to assess the performance of health service provision and predict treatment adherence and outcomes. This study aimed to assess human HIV/AIDS patients' expectation of and satisfaction with the pharmaceutical service delivered at Gondar University Referral Hospital, Ethiopia. Patients and methods: An institution-based cross-sectional study was performed from May 11 to 25, 2015. A total of 291 patients living with HIV/AIDS were included using a simple random sampling method. Data were collected using structured questionnaires measuring expectation and satisfaction of respondents using a Likert scale of 1-5 through face-to-face interviews. The data collected were entered into and analyzed using Statistical Packages for Social Sciences. Comparison was made between those respondents who lived in and outside the town. Results: The overall mean expectation and satisfaction of respondents toward pharmacy setting and services were 3.62 and 3.13, respectively. More than half (56.1%) of the participants were dissatisfied with the comfort and convenience of waiting area and private counseling room. Similarly, 69.3% of the respondents claimed that pharmacy professionals did not give information about side effects and drug-drug and drug-food interactions of antiretroviral medications. There was a statistically significant difference between respondents who live in and outside Gondar town in overall expectation (t=3.415, P=0.001) with the pharmacy setting and services. Conclusion: In this study, the overall satisfaction level of respondents with pharmaceutical service (pharmacy setting and services) provided at Gondar University Referral Hospital was found to be low, while the overall respondents' expectation from the pharmaceutical services were exceedingly high. The hospital should implement good dispensing practice systems in relation to the services and continuing professional development to professionals in order to improve the satisfaction of patients. [ABSTRACT FROM AUTHOR]
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- 2016
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27. Extent of dispensing prescription-only medications without a prescription in community drug retail outlets in Addis Ababa, Ethiopia: a simulated-patient study.
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Erku, Daniel Asfaw, Mekuria, Abebe Basazn, Surur, Abdrrahman Shemsu, and Gebresillassie, Begashaw Melaku
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RETAIL stores ,ANTIBIOTICS ,CROSS-sectional method ,GLIBENCLAMIDE ,RESPIRATORY infections ,DRUG side effects - Abstract
Purpose: This study was aimed at assessing the extent of dispensing prescription-only medications without a prescription in community drug retail outlets (CDROs) of Addis Ababa, Ethiopia. Methods: A descriptive cross-sectional observational study design was used to sample 31 pharmacies, 25 drug stores, and two rural drug vendors from August 11, 2015, to October 21, 2015, through a simple random sampling method. A simulated-patient method of visit was implemented to collect data. Requests of six tracer prescription-only medicines (amoxicillin + clavulanic acid capsule, amitriptyline, captopril, glibenclamide [also known as glyburide], omeprazole capsule, and sildenafil citrate) and upper respiratory tract infection were selected as the simulated clinical scenario. Results: Amoxicillin-clavulanic acid capsule was dispensed when requested in 87.93% of the dispensaries. All of the CDROs dispensed omeprazole upon request. Sildenafil citrate (Viagra) was in stock in 96.55% of the CDROs, all of which issued the requested number of tablets without asking why or for whom the drug was needed. Amitriptyline, captopril, and glibenclamide (glyburide) were dispensed in 84.48%, 89.65%, and 87.93% of CDROs upon the provision of an empty container. Antibiotics were obtained from 75.86% of CDROs for presentation of upper respiratory tract infection symptoms. Among the dispensed antibiotics, the most common was amoxicillin (93.18%), followed by amoxicillin-clavulanic acid capsule (72.72%), and azithromycin (50%). Only 4.5% of the dispensaries asked about drug allergies, and 15.9% of the CDROs informed the simulated patient about the possible side effects of the drugs. Conclusion: This study revealed a very high rate of dispensing of prescription-only medicines without a prescription. Antimicrobials and drugs for chronic diseases were obtained with ease from almost all of the randomly sampled CDROs. Putting good dispensing practice into effect and adhering to the existing national laws and regulations regarding the same are necessary. It is also necessary to adopt a strong and explicit line of action, especially toward the irrational use of antibiotics. [ABSTRACT FROM AUTHOR]
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- 2016
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28. A systematic review of scope and quality of health economic evaluations conducted in Ethiopia
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Daniel Erku, Amanual G Mersha, Eskinder Eshetu Ali, Gebremedhin B Gebretekle, Befikadu L Wubishet, Gizat Molla Kassie, Anwar Mulugeta, Alemayehu B Mekonnen, Tesfahun C Eshetie, Paul Scuffham, Erku, Daniel, Mersha, Amanual G, Ali, Eskinder Eshetu, Gebretekle, Gebremedhin B, Wubishet, Befikadu L, Kassie, Gizat Molla, Mulugeta, Anwar, Mekonnen, Alemayehu B, Eshetie, Tesfahun C, and Scuffham, Paul
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economic evaluation ,Technology Assessment, Biomedical ,Cost-Benefit Analysis ,Health Policy ,Humans ,Ethiopia ,Child ,cost-effectiveness - Abstract
There has been an increased interest in health technology assessment and economic evaluations for health policy in Ethiopia over the last few years. In this systematic review, we examined the scope and quality of healthcare economic evaluation studies in Ethiopia. We searched seven electronic databases (PubMed/MEDLINE, EMBASE, PsycINFO, CINHAL, Econlit, York CRD databases and CEA Tufts) from inception to May 2021 to identify published full health economic evaluations of a health-related intervention or programme in Ethiopia. This was supplemented with forward and backward citation searches of included articles, manual search of key government websites, the Disease Control Priorities-Ethiopia project and WHO-CHOICE programme. The quality of reporting of economic evaluations was assessed using the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) checklist. The extracted data were grouped into subcategories based on the subject of the economic evaluation, organized into tables and reported narratively. This review identified 34 full economic evaluations conducted between 2009 and 2021. Around 14 (41%) of studies focussed on health service delivery, 8 (24%) on pharmaceuticals, vaccines and devices, and 4 (12%) on public-health programmes. The interventions were mostly preventive in nature and focussed on communicable diseases (n = 19; 56%) and maternal and child health (n = 6; 18%). Cost-effectiveness ratios varied widely from cost-saving to more than US $37 313 per life saved depending on the setting, perspectives, types of interventions and disease conditions. While the overall quality of included studies was judged as moderate (meeting 69% of CHEERS checklist), only four out of 27 cost-effectiveness studies characterized heterogeneity. There is a need for building local technical capacity to enhance the design, conduct and reporting of health economic evaluations in Ethiopia.
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- 2021
29. The prognosis of heart failure patients: Does sodium level play a significant role?
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Tadesse Melaku Abegaz, Daniel Asfaw Erku, Tamrat Abebe, Yonas Getaye Tefera, Begashaw Melaku Gebresillassie, Eyob Alemayehu Gebreyohannes, Sewunet Admasu Belachew, Akshaya Srikanth Bhagavathula, Abebe, Tamrat Befekadu, Gebreyohannes, Eyob Alemayehu, Tefera, Yonas Getaye, Bhagavathula, Akshaya Srikanth, Erku, Daniel Asfaw, Belachew, Sewunet Admasu, Gebresillassie, Begashaw Melaku, and Abegaz, Tadesse Melaku
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Male ,hyponatremia ,lcsh:Medicine ,heart failure ,Kaplan-Meier Estimate ,030204 cardiovascular system & hematology ,Cardiovascular Medicine ,Biochemistry ,Cohort Studies ,0302 clinical medicine ,Atrial Fibrillation ,Medicine and Health Sciences ,Prevalence ,030212 general & internal medicine ,lcsh:Science ,Diuretics ,Multidisciplinary ,Mortality rate ,Medical record ,Drugs ,Middle Aged ,Prognosis ,Cardiovascular Diseases ,Creatinine ,Female ,Hyponatremia ,Arrhythmia ,Cohort study ,Research Article ,Adult ,medicine.medical_specialty ,Death Rates ,Cardiology ,cardiovascular disorder ,03 medical and health sciences ,Population Metrics ,Diagnostic Medicine ,Internal medicine ,medicine ,Humans ,Survival analysis ,Aged ,Retrospective Studies ,Pharmacology ,Heart Failure ,Population Biology ,business.industry ,lcsh:R ,Sodium ,nutritional and metabolic diseases ,Biology and Life Sciences ,Correction ,Retrospective cohort study ,medicine.disease ,Clinical trial ,Heart failure ,lcsh:Q ,Ethiopia ,business ,Biomarkers - Abstract
usc Introduction: Heart failure (HF), a major cardiovascular disorder, remains a grievous clinical condition regardless of advances in medical care. Hyponatremia is classified as a serum sodium concentration of
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- 2018
30. Recreational Use of Phosphodiesterase 5 Inhibitors and Its Associated Factors among Undergraduate Male Students in an Ethiopian University: A Cross-Sectional Study
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Sewunet Admasu Belachew, Yonas Getaye Tefera, Eyob Alemayehu Gebreyohannes, Akshaya Srikanth Bhagavathula, Daniel Asfaw Erku, Begashaw Melaku Gebresillassie, Gebreyohannes, Eyob Alemayehu, Bhagavathula, Akshaya Srikanth, Gebresillassie, Begashaw Melaku, Tefera, Yonas Getaye, Sewunet, Admasu, and Erku, Daniel Asfaw
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Male ,Aging ,medicine.medical_specialty ,erectile dysfunction ,Cross-sectional study ,Urology ,lcsh:Medicine ,Recreational use ,lcsh:RC870-923 ,Logistic regression ,03 medical and health sciences ,0302 clinical medicine ,male ,medicine ,Pharmacology (medical) ,Erectile dysfunction ,Phosphodiesterase 5 inhibitors ,030212 general & internal medicine ,Sildnafil citrate ,Gynecology ,030505 public health ,business.industry ,Health Policy ,lcsh:R ,phosphodiesterase 5 inhibitors ,Public Health, Environmental and Occupational Health ,Odds ratio ,lcsh:Diseases of the genitourinary system. Urology ,medicine.disease ,Confidence interval ,Psychiatry and Mental health ,Reproductive Medicine ,cGMP-specific phosphodiesterase type 5 ,Original Article ,Ethiopia ,Substance use ,0305 other medical science ,business ,sildnafil citrate ,Demography - Abstract
usc Purpose: To assess the prevalence of phosphodiesterase 5 (PDE5) inhibitor use and associated factors among University of Gondar undergraduate students. Materials and Methods: An institution-based, cross-sectional study, using a survey questionnaire, was conducted from October to December 2015 to assess PDE5 inhibitor use and associated factors among male students at the University of Gondar. A Self-Esteem and Relationship questionnaire (14 items), an International Index of Erectile Function questionnaire (15 items) and a questionnaire on PDE5 inhibitor use (14 items) were included in the survey. Results: Across all respondents (age, 21.9±1.88 years), more than half (55.7%, n=233) had heard about PDE5 inhibitors, but only 23 men (5.5%) reported trying a PDE5 inhibitor drug at least once. Older students were more likely to use PDE5 inhibitors compared to younger students (adjusted odds ratio [AOR], 1.40; 95% confidence interval [CI], 1.109~1.768). Those students who were smokers were 5.15 times more likely to use PDE5 inhibitors as compared to their non-smoking counterparts (AOR, 5.15; 95% CI, 2.096~12.687). In addition, multivariate logistic regression showed that being in a relationship, alcohol use, greater number of cigarettes smoked per day, and more sexual partners were significantly associated with PDE5 inhibitor use. Conclusions: The prevalence of PDE5 inhibitor use among undergraduate students was 5.5%. Cigarette smoking and other substance use, older age, and greater number of sexual partners were significantly associated factors for PDE5 inhibitor use. These findings suggest that restricting access to PDE5 inhibitor drugs is essential to curtailing misuse among university students. Refereed/Peer-reviewed
- Published
- 2016
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