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Your search keyword '"Xiao-Chong Chen"' showing total 2 results
Start Over Author "Xiao-Chong Chen" Topic eutypella
2 results on '"Xiao-Chong Chen"'

1. Eutypenoids A–C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1

Author

Liu-Qiang Zhang, Xiao-Chong Chen, Zhao-Qiang Chen, Gui-Min Wang, Shi-Guo Zhu, Yi-Fu Yang, Kai-Xian Chen, Xiao-Yu Liu, and Yi-Ming Li

Subjects
eutypenoid, novel pimarane diterpenes, Eutypella, Arctic fungi, immunosuppressive effect, Biology (General), QH301-705.5
Abstract

Eutypenoids A–C (1–3), pimarane diterpenoid alkaloid and two ring A rearranged pimarane diterpenoids, were isolated from the culture of Eutypella sp. D-1 obtained from high-latitude soil of the Arctic. Their structures, including absolute configurations, were authenticated on the basis of the mass spectroscopy (MS), nuclear magnetic resonance (NMR), X-ray crystallography, and electronic circular dichroism (ECD) analysis. The immunosuppressive effects of eutypenoids A–C (1–3) were studied using a ConA-induced splenocyte proliferation model, which suggested that 2 exhibited potent immunosuppressive activities.

Published
2016
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2. Eutypenoids A–C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1

Author

Shi-Guo Zhu, Xiao-Chong Chen, Guimin Wang, Zhaoqiang Chen, Yifu Yang, Xiao-Yu Liu, Liuqiang Zhang, Yiming Li, and Kaixian Chen

Subjects
Circular dichroism, Magnetic Resonance Spectroscopy, Stereochemistry, Pharmaceutical Science, eutypenoid, novel pimarane diterpenes, Eutypella, Arctic fungi, immunosuppressive effect, Fungus, Crystallography, X-Ray, 01 natural sciences, Article, Mass Spectrometry, Mice, Ascomycota, Drug Discovery, Concanavalin A, Splenocyte, Animals, lcsh:QH301-705.5, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Soil Microbiology, Cell Proliferation, Mice, Inbred BALB C, biology, Arctic Regions, 010405 organic chemistry, Chemistry, Circular Dichroism, Alkaloid, Nuclear magnetic resonance spectroscopy, biology.organism_classification, Terpenoid, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, lcsh:Biology (General), Abietanes, Immunosuppressive Agents, Spleen
Abstract

Eutypenoids A–C (1–3), pimarane diterpenoid alkaloid and two ring A rearranged pimarane diterpenoids, were isolated from the culture of Eutypella sp. D-1 obtained from high-latitude soil of the Arctic. Their structures, including absolute configurations, were authenticated on the basis of the mass spectroscopy (MS), nuclear magnetic resonance (NMR), X-ray crystallography, and electronic circular dichroism (ECD) analysis. The immunosuppressive effects of eutypenoids A–C (1–3) were studied using a ConA-induced splenocyte proliferation model, which suggested that 2 exhibited potent immunosuppressive activities.

Published
2016
Full Text
View/download PDF

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