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The human brain's ability to quickly detect dangerous stimuli is crucial in selecting appropriate responses to possible threats. Trait anxiety has been suggested to moderate these processes on certain processing stages. To dissociate such different information-processing stages, research using classical conditioning has begun to examine event-related potentials (ERPs) in response to fear-conditioned (CS +) faces. However, the impact of trait anxiety on ERPs to fear-conditioned faces depending on specific task conditions is unknown. In this preregistered study, we measured ERPs to faces paired with aversive loud screams (CS +) or neutral sounds (CS −) in a large sample (N = 80) under three different task conditions. Participants had to discriminate face-irrelevant perceptual information, the gender of the faces, or the CS category. Results showed larger amplitudes in response to aversively conditioned faces for all examined ERPs, whereas interactions with the attended feature occurred for the P1 and the early posterior negativity (EPN). For the P1, larger CS + effects were observed during the perceptual distraction task, while the EPN was increased for CS + faces when deciding about the CS association. Remarkably, we found no significant correlations between ERPs and trait anxiety. Thus, fear-conditioning potentiates all ERP amplitudes, some processing stages being further modulated by the task. However, the finding that these ERP differences were not affected by individual differences in trait anxiety does not support theoretical accounts assuming increased threat processing or reduced threat discrimination depending on trait anxiety.

Faces with emotional information–by virtue of their expression or their history of affective learning–are prioritized during neuronal processing as compared to neutral faces. Classical conditioning studies have shown that aversively conditioned (CS+) faces potentiate different face processing stages as evidenced by increased early and late event-related potential (ERPs) components. However, it is unknown whether and how ERP modulations depend on certain attentional conditions. To examine this question, this preregistered study investigated ERPs to faces paired with aversive screams or neutral sounds under three tasks with increasing attention to CS + relevant features of the face: Participants (N = 40) had to discriminate either the orientation of superimposed lines, perceived gender, or the CS association. We found potentiation of the N170, the Early Posterior Negativity (EPN), and, most remarkably, the Late Positive Potential (LPP) to CS + faces regardless of task condition. This finding suggests that, in contrast to other types of emotional information and learning, classical conditioning boosts early and late processing stages, even if no explicit attention to the face information or the CS association is required.

Our brains rapidly respond to human faces and can differentiate between many identities, retrieving rich semantic emotional-knowledge information. Studies provide a mixed picture of how such information affects event-related potentials (ERPs). We systematically examined the effect of feature-based attention on ERP modulations to briefly presented faces of individuals associated with a crime. The tasks required participants ( N = 40 adults) to discriminate the orientation of lines overlaid onto the face, the age of the face, or emotional information associated with the face. Negative faces amplified the N170 ERP component during all tasks, whereas the early posterior negativity (EPN) and late positive potential (LPP) components were increased only when the emotional information was attended to. These findings suggest that during early configural analyses (N170), evaluative information potentiates face processing regardless of feature-based attention. During intermediate, only partially resource-dependent, processing stages (EPN) and late stages of elaborate stimulus processing (LPP), attention to the acquired emotional information is necessary for amplified processing of negatively evaluated faces.

Dyadic interactions are associated with the exchange of personality-related messages, which can be congruent or incongruent with one’s self-view. In the current preregistered study ( N = 52), we investigated event-related potentials (ERPs) toward real social evaluations in order to uncover the neural mechanisms underlying the processing of congruent and incongruent evaluative feedback. Participants interacted first, and then during an electroencephalogram (EEG) session, they received evaluations from their interaction partner that were either congruent or incongruent with their own ratings. Findings show potentiated processing of self-related incongruent negative evaluations at early time points (N1) followed by increased processing of both incongruent negative and positive evaluations at midlatency time windows (early posterior negativity) and a prioritized processing of self-related incongruent positive evaluations at late time points (feedback-related P3, late positive potential). These findings reveal that, after real social interactions, evaluative feedback about oneself that violates one’s self-view modulates all processing stages with an early negativity and a late positivity bias.

Faces transmit rich information about a unique personal identity. Recent studies examined how negative evaluative information affects event-related potentials (ERPs), the relevance of individual differences, such as trait anxiety, neuroticism, or agreeableness, for these effects is unclear. In this preregistered study, participants (N = 80) were presented with neutral faces, either associated with highly negative or neutral biographical information. Faces were shown under three different task conditions that varied the attentional focus on face-unrelated features, perceptual face information, or emotional information. Results showed a task-independent increase of the N170 component for faces associated with negative information, while interactions occurred for the Early Posterior Negativity (EPN) and the Late Positive Potential (LPP), showing ERP differences only when paying attention to the evaluative information. Trait anxiety and neuroticism did not influence ERP differences. Low agreeableness increased EPN differences during perceptual distraction. Thus, we observed that low agreeableness leads to early increased processing of potentially hostile faces, although participants were required to attend to a face-unrelated feature. Supplementary Information The online version contains supplementary material available at 10.3758/s13415-021-00894-w.

Depression is associated with abnormalities in patterns of information processing, particularly in the context of processing of interpersonal information. The present study was designed to investigate the differences in depressive individuals in cortical processing of facial stimuli when neutral faces were presented in a context that involved information about emotional valence as well as self-reference. In 21 depressive patients and 20 healthy controls, event-related potentials (ERPs) were recorded during the presentation of neutral facial expressions, which were accompanied by affective context information that was either self- or other-related. Across conditions, depressive patients showed larger mean P100 amplitudes than healthy controls. Furthermore, mean late positive potential (LPP) amplitudes of depressive patients were larger in response to faces in self-related than in other-related context. In addition, irrespective of self-reference, mean LPP responses of depressive patients to faces presented after socially threatening sentences were larger compared with faces presented after neutral sentences. Results regarding self-reference supported results of previous studies indicating larger mean amplitudes in self-related conditions. Findings suggest a general heightened initial responsiveness to emotional cues and a sustained emotion processing of socially threatening information in depressive patients. Supplementary Information The online version contains supplementary material available at 10.3758/s13415-021-00877-x.

There is an ongoing debate on how different components of the event-related potential (ERP) to threat-related facial expressions are modulated by attentional conditions and interindividual differences in trait anxiety. In the current study (N = 80), we examined ERPs to centrally presented, task-irrelevant fearful and neutral faces, while participants had to solve a face-unrelated visual task, which differed in difficulty and spatial position. Critically, we used a fixation-controlled experimental design and ensured the spatial attention manipulation by spectral analysis of the EEG. Besides the factors emotion, spatial attention, and perceptual load, we also investigated correlations between trait anxiety and ERPs. While P1 emotion effects were insignificant, the N170 was increased to fearful faces regardless of load and spatial attention conditions. During the EPN time window, a significantly increased negativity for fearful faces was observed only during low load and spatial attention to the face. We found no significant relationship between ERPs and trait anxiety, questioning the hypothesis of a general hypersensitivity toward fearful expressions in anxious individuals. These results show a high resistance of the N170 amplitude increase for fearful faces to spatial attention and task load manipulations. By contrast, the EPN modulation by fearful faces index a resource-dependent stage of the ERP, requiring both spatial attention at the location of faces and low load of the face-irrelevant task.

Higher social relevance has been shown to modulate event-related potentials (ERPs). It is unclear whether such modulations can be observed if one only imagines stimuli to be socially relevant. In a preregistered EEG study (

Paying attention to faces is of special interest for humans as well as for scientific research. The experimental manipulation of facial information offers an ecologically valid approach to investigate emotion, attention and social functioning. Humans are highly specialized in face perception and event-related brain potentials (ERP) provide insights into the temporal dynamics of involved neuronal mechanisms. Here, we summarize ERP research from the last decade, examining the processing of emotional compared to neutral facial expressions along the visual processing stream. A particular focus lies on exploring the impact of attention tasks on early (P1, N170), mid-latency (P2, EPN) and late (P3, LPP) stages of processing. This review systematizes facial emotion effects as a function of different attention tasks: 1) When faces serve as mere distractors, 2) during passive viewing designs, 3) directing attention at faces in general, and 4) paying attention to facial expressions. We find fearful and angry expressions to reliably modulate the N170, EPN, and LPP component, the latter benefiting from attention directed at the emotional facial expression.

Face processing is biased by emotional and voluntarily directed attention, both of which modulate processing in distributed cortical areas. The amygdala is assumed to contribute to an attentional bias for emotional faces, although its interaction with directed attention awaits further clarification. Here, we studied the interaction of emotion and attention during face processing via scalp EEG potentials of healthy participants and intracranial EEG (iEEG) recordings of the right amygdala in one patient. Three randomized blocks consisting of angry, neutral, and happy facial expressions were presented, and one expression was denoted as the target category in each block. Happy targets were detected fastest and most accurately both in the group study and by the iEEG patient. Occipital scalp potentials revealed emotion differentiation for happy faces in the early posterior negativity (EPN) around 300 ms after stimulus onset regardless of the target condition. A similar response to happy faces occurred in the amygdala only for happy targets. On the scalp, a late positive potential (LPP, around 600 ms) enhancement for targets occurred for all target conditions alike. A simultaneous late signal in the amygdala was largest for emotional targets. No late signal enhancements were found for neutral targets in the amygdala. Cortical modulations, by contrast, showed both attention-independent effects of emotion and emotion-independent effects of attention. These results demonstrate an attention-dependence of amygdala activity during the processing of facial expressions and partly independent cortical mechanisms.

Prioritized processing of fearful compared to neutral faces has been proposed to result from evolutionary adaptation of the contrast sensitivity function (CSF) to the features of emotionally relevant faces and/or vice versa. However, it is unknown whether a stimulus merely has to feature the amplitude spectrum of a fearful face to be prioritized or whether the relevant spatial frequencies have to occur with specific phases and orientations. Prioritized processing is indexed by specific increases of Event-Related Potentials (ERPs) of the EEG and occurs throughout different early processing stages, indexed by emotion-related modulations of the P1, N170, and EPN. In this pre-registered study, we manipulated phase and amplitude properties of the Fourier spectra of neutral and fearful faces to test the effect of phase coherence (PC, face vs. scramble) and orientation coherence (OC, original vs. rotational average) and their interactions with differential emotion processing. We found that differential emotion processing was not present at the level of P1 but strongly affected N170 and EPN. In both cases, intact phase coherence was required for enhanced processing of fearful faces. OC did not interact with emotion. While faces produced the typical N170 effect, we observed a reversed effect for scrambles. Additional exploratory independent component analysis (ICA) suggests that this reversal could signal a mismatch between an early "perceptual hypothesis" and feedback of configural information. In line with our expectations, fearful-neutral differences for the N170 and EPN depend on configural information, i.e., recognizable faces.

A large body of research suggests that early event-related potentials (ERPs), such as the P1 and N1, are potentiated by attention and represent stimulus amplification. However, recent accounts suggest that the P1 is associated with inhibiting the irrelevant visual field evidenced by a pronounced ipsilateral P1 during sustained attention to peripherally presented stimuli. The current EEG study further investigated this issue to reveal how lateralized ERP findings are modulated by face and emotional information. Therefore, participants were asked to fixate the center of the screen and pay sustained attention either to the right or left visual field, where angry or neutral faces or their Fourier phase-scrambled versions were presented. We found a bilateral P1 to all stimuli with relatively increased, but delayed, ipsilateral P1 amplitudes to faces but not to scrambles. Explorative independent component analyses dissociated an earlier lateralized larger contralateral P1 from a later bilateral P1. By contrast, the N170 showed a contralateral enhancement to all stimuli, which was most pronounced for neutral faces attended in the left hemifield. Finally, increased contralateral alpha power was found for both attended hemifields but was not significantly related to poststimulus ERPs. These results provide evidence against a general inhibitory role of the P1 but suggest stimulus-specific relative enhancements of the ipsilateral P1 for the irrelevant visual hemifield. The lateralized N170, however, is associated with stimulus amplification as a function of facial features.

Several components of the event-related potential (ERP) are amplified by emotional compared to neutral pictures. This study (N = 80) investigated systematically how attention to specific stimulus features influences ERPs to briefly presented (100 ms) negative and neutral pictures. Participants had to discriminate either (i) the orientation of overlaid lines, (ii) if the picture content was animate or inanimate, or (iii) if the emotional content was negative or neutral. ERP results showed interactions between the attention task and emotion processing for the early posterior negativity (EPN) and the late positive potential (LPP). For the EPN, attention to distracting perceptual information reduced emotional differences, while at the level of the LPP, emotion effects were selectively amplified when participants attended to the emotional content. These findings reveal the time-dependent effects of feature-based attention tasks on ERPs to emotional pictures.

In neuroscientific studies, the naturalness of face presentation differs; a third of published studies makes use of close-up full coloured faces, a third uses close-up grey-scaled faces and another third employs cutout grey-scaled faces. Whether and how these methodological choices affect emotion-sensitive components of the event-related brain potentials (ERPs) is yet unclear. Therefore, this pre-registered study examined ERP modulations to close-up full-coloured and grey-scaled faces as well as cutout fearful and neutral facial expressions, while attention was directed to no-face oddballs. Results revealed no interaction of face naturalness and emotion for any ERP component, but showed, however, large main effects for both factors. Specifically, fearful faces and decreasing face naturalness elicited substantially enlarged N170 and early posterior negativity amplitudes and lower face naturalness also resulted in a larger P1.This pattern reversed for the LPP, showing linear increases in LPP amplitudes with increasing naturalness. We observed no interaction of emotion with face naturalness, which suggests that face naturalness and emotion are decoded in parallel at these early stages. Researchers interested in strong modulations of early components should make use of cutout grey-scaled faces, while those interested in a pronounced late positivity should use close-up coloured faces.

Fearful facial expressions are prioritized across different stages of information processing as reflected by early, mid-latency, and late components of event-related brain potentials (ERP). Trait anxiety has been proposed to modulate these responses, but it is yet unclear how such modulations depend on feature-based attention. In this preregistered study (N = 80), we investigated the effects of trait anxiety on ERP differences between fearful and neutral faces across three different tasks. Participants had to discriminate either the orientation of lines overlaid onto the faces, the gender of the face, or the emotional expression, thus increasing attention to emotionally relevant facial features across the tasks. Fearful versus neutral faces elicited increased P1 and N170 amplitudes across tasks and potentiated amplitudes when attention was directed to faces (early posterior negativity [EPN]) or the expression (EPN and late positive potential). Higher trait anxiety was related to smaller EPN differences between fearful and neutral faces during the perceptual discrimination task. This early relationship suggests reduced instead of amplified processing of fearful faces for high trait anxious participants under perceptual distraction.

Load Theory assumes that the extent of processing of task-irrelevant information depends on the level (high vs. low load) and type (perceptual vs. working memory) of task load. In this review, we address the neuroscientific perspective on Load Theory by a systematic evaluation of neuroimaging and electrophysiological studies, which manipulated perceptual or working memory load and reported brain responses to task-irrelevant unimodal and crossmodal stimuli. Studies show: (1) Load effects can be observed across the whole processing stream from subcortical areas to higher cortical areas, (2) both higher perceptual and working memory load lead to decreased distractor processing, (3) event-related potential studies suggest that load effects occur more reliably the later the ERP component and (4) load effects occur both within and across modalities. Thus, findings are at least partially consistent with assumptions of Load Theory. Based on the reviewed studies and theoretical and methodological considerations, we provide several suggestions, which might help to improve future research in the field.

The temporal dynamics of top-down voluntary and bottom-up driven emotional attention are a matter of debate. Both emotion and task-relevance have been shown to affect the early posterior negativity (EPN) and the late positive potential (LPP) during the processing of emotional pictures, whereas there are mixed findings related to interactions of emotion and task-relevance. In this preregistered study, we used Bayesian models to test this interplay between emotion and task-relevance. Participants (N = 104) were presented negative, neutral, and positive International Affective Picture System (IAPS) pictures, and block-wise were asked to respond either to negative, neutral, or positive pictures, rendering one stimulus category task-relevant and the remaining stimuli task-irrelevant. Bayesian models showed evidence for the absence of interactions between task-relevance and emotion. Furthermore, models showed parallel emotion and task effects for the EPN and late stages of the LPP. Additional interactive effects were found during an early LPP interval (400 to 600 ms), with increased LPP amplitudes when emotion was rendered task-relevant. Taken together, the results revealed distinct but parallel temporal onsets of task-relevance and emotion effects, followed by task and emotion interactions in the early LPP. Thus, based on this high-powered study employing Bayesian analysis, evidence is provided that interactions between task-relevance and emotion do not emerge before the LPP time window. These results further inform theories proposing early parallel and late interactive processes of the emotional salience of stimuli and top-down attention.

Emotional facial expressions lead to modulations of early event-related potentials (ERPs). However, it has so far remained unclear how far these modulations represent face-specific effects rather than differences in low-level visual features, and to which extent they depend on available processing resources. To examine these questions, we conducted two preregistered independent experiments (N = 40 in each experiment) using different variants of a novel task that manipulates peripheral perceptual load across levels but keeps overall visual stimulation constant. At the display center, we presented task-irrelevant angry, neutral, and happy faces and their Fourier phase-scrambled versions, which preserved low-level visual features. The results of both studies showed load-independent P1 and N170 emotional expression effects. Importantly, by using Bayesian analyses we could confirm that these facial expression effects were face-independent for the P1 but not for the N170 component. We conclude that firstly, ERP modulations during the P1 interval strongly depend on low-level visual information, while the N170 modulation requires the processing of figural facial expression features. Secondly, both P1 and N170 modulations appear to be immune to a large range of variations in perceptual load.

Prioritized processing of fearful compared to neutral faces is reflected in behavioral advantages such as lower detection thresholds, but also in enhanced early and late event-related potentials (ERPs). Behavioral advantages have recently been associated with the spatial frequency spectrum of fearful faces, better fitting the human contrast sensitivity function than the spectrum of neutral faces. However, it is unclear whether and to which extent early and late ERP differences are due to low-level spatial frequency spectrum information or high-level representations of the facial expression. In this pre-registered EEG study (N = 38), the effects of fearful-specific spatial frequencies on event-related ERPs were investigated by presenting faces with fearful and neutral expressions whose spatial frequency spectra were manipulated so as to contain either the average power spectra of neutral, fearful, or both expressions combined. We found an enlarged N170 to fearful versus neutral faces, not interacting with spatial frequency. Interactions of emotional expression and spatial frequencies were observed for the P1 and Early Posterior Negativity (EPN). For both components, larger emotion differences were observed when the spectrum contained neutral as opposed to fearful frequencies. Importantly, for the EPN, fearful and neutral expressions did not differ anymore when inserting fearful frequencies into neutral expressions, whereas typical emotion differences were found when faces contained average or neutral frequencies. Our findings show that N170 emotional modulations are unaffected by expression-specific spatial frequencies. However, expression-specific spatial frequencies alter early and mid-latency ERPs. Most notably, the EPN to neutral expressions is boosted by adding fearful spectra-but not vice versa.

Post-traumatic stress disorder (PTSD) is associated with a hypersensitivity to potential threat. This hypersensitivity manifests through differential patterns of emotional information processing and has been demonstrated in behavioral and neurophysiological experimental paradigms. However, the majority of research has been focused on adult patients with PTSD. To examine possible differences in underlying neurophysiological patterns for adolescent patients with PTSD after childhood sexual and/or physical abuse (CSA/CPA), ERP correlates of emotional word processing in 38 healthy participants and 40 adolescent participants with PTSD after experiencing CSA/CPA were studied. The experimental paradigm consisted of a passive reading task with neutral, positive (e.g., paradise), physically threatening (e.g., torment), and socially threatening (i.e., swearing, e.g., son of a bitch) words. A modulation of P3 amplitudes by emotional valence was found, with positive words inducing less elevated amplitudes over both groups. Interestingly, in later processing, the PTSD group showed augmented early late positive potential (LPP) amplitudes for socially threatening stimuli, while there were no modulations within the healthy control group. Also, region-specific emotional modulations for anterior and posterior electrode clusters were found. For the anterior LPP, highest activations have been found for positive words, while socially and physically threatening words led to strongest modulations in the posterior LPP cluster. There were no modulations by group or emotional valence at the P1 and EPN stage. The findings suggest an enhanced conscious processing of socially threatening words in adolescent patients with PTSD after CSA/CPA, pointing to the importance of a disjoined examination of threat words in emotional processing research. © 2019 The Authors Psychophysiology published by Wiley Periodicals, Inc. on behalf of Society for Psychophysiological Research.

High perceptual load is thought to impair the early processing of task-irrelevant distractors. In contrast, for emotional faces, previous studies have shown that early event-related potentials (ERPs), the P1, the N170, and, albeit to a lesser degree, the EPN, are relatively resistant to perceptual load manipulations. However, the temporal dynamics of the interaction between load and processing of emotional distractor faces have been neglected so far. In this preregistered EEG study (N = 40), we investigated effects of perceptual load and different interstimulus intervals (ISIs) on ERPs to fearful and neutral task-irrelevant faces. We used a task with identical visual input regardless of perceptual load (high vs. low), and four ISIs between task and face onset (100 ms, 300 ms, 600 ms, 900 ms). Results show that emotional ERP modulations depend on load manipulations as well as on specific ISIs between the perceptual task and face onset. Emotional P1 effects were modulated by load, irrespective of the ISI, while emotional N170 and EPN effects were independent of load, but modulated by the ISI. In particular, emotion effects for the EPN were only observed after a prolonged period between load task and face onset (ISI900), suggesting a strong vulnerability of this component to any competing task. Taken together, our findings show that early ERP components for fearful expressions show dissociable responses to load and timing manipulations.

Processing affectively charged visual stimuli typically results in increased amplitude of specific event-related potential (ERP) components. Low-level features similarly modulate electrophysiological responses, with amplitude changes proportional to variations in stimulus size and contrast. However, it remains unclear whether emotion-related amplifications during visual word processing are necessarily intertwined with changes in specific low-level features or, instead, may act independently. In this pre-registered electrophysiological study, we varied font size and contrast of neutral and negative words while participants were monitoring their semantic content. We examined ERP responses associated with early sensory and attentional processes as well as later stages of stimulus processing. Results showed amplitude modulations by low-level visual features early on following stimulus onset – i.e., P1 and N1 components –, while the LPP was independently modulated by these visual features. Independent effects of size and emotion were observed only at the level of the EPN. Here, larger EPN amplitudes for negative were observed only for small high contrast and large low contrast words. These results suggest that early increase in sensory processing at the EPN level for negative words is not automatic, but bound to specific combinations of low-level features, occurring presumably via attentional control processes.

Background Migraine is a disorder of periodic disabling headache. Facilitated cortical responsivity has been suggested as one predisposing factor. Although the underlying mechanisms of migraine attack onsets are not fully understood, facilitated cortical responsivity has been suggested as one predisposing factor. Here, we investigate if enhanced cortical responsivity is reflected in altered event-related potentials during processing of complex pictures. Method Altogether, 16 migraine patients and 16 healthy volunteers participated in this study. Each patient had a diagnosed migraine and was headache- and medication-free for the study. Participants watched positive, negative and neutral pictures from the international affective picture system. An electroencephalogram was recorded during picture presentation. Afterwards, participants were asked to rate the pictures for valence and arousal. Results Migraine patients showed significantly more negative-going early event-related potential components from 100 ms to 180 ms to all picture categories over occipital regions as well as more positive-going late potentials over central regions. Patients and controls did not differ in valence and arousal ratings for the international-affective picture system. Discussion Patients with migraine seem to react cortically more intensely to all kinds of pictorial stimuli, regardless of emotional content. This facilitated processing may be related to the high cortical responsivity shown in various other event-related potential studies and might contribute to the recurring intense headache attacks.

Recent studies have shown that the perceptual processing of human faces is affected by context information, such as previous experiences and information about the person represented by the face. The present study investigated the impact of verbally presented information about the person that varied with respect to affect (neutral, physically threatening, socially threatening) and reference (self-referred, other-referred) on the processing of faces with an inherently neutral expression. Stimuli were presented in a randomized presentation paradigm. Event-related potential (ERP) analysis demonstrated a modulation of the evoked potentials by reference at the EPN (early posterior negativity) and LPP (late positive potential) stage and an enhancing effect of affective valence on the LPP (700-1000 ms) with socially threatening context information leading to the most pronounced LPP amplitudes. We also found an interaction between reference and valence with self-related neutral context information leading to more pronounced LPP than other related neutral context information. Our results indicate an impact of self-reference on early, presumably automatic processing stages and also a strong impact of valence on later stages. Using a randomized presentation paradigm, this study confirms that context information affects the visual processing of faces, ruling out possible confounding factors such as facial configuration or conditional learning effects.

Recently, several event-related potential (ERP) studies investigated the impact of sender attributions on language-based social feedback processing. Results showed very early responses to the social context, while interactions or effects of emotional content started later. However, in these studies, sender attribution was varied across blocks, possibly inducing unspecific, anticipatory effects. Here, who was giving feedback was disclosed simultaneously with the decision itself. Participants' ERPs differentiated between attributed senders starting with the early posterior negativity. P3 and late positive potential (LPP) amplitudes were also enlarged for the "human sender". Emotion effects occurred in the P3 and LPP time windows. Further, we found an interaction on the P3: "Human" emotional feedback was selectively amplified. Source analysis localized enhanced processing of "human"-generated feedback in visual areas from around 300 ms after feedback onset and from 400 ms also in temporal regions. Enhancement of "human" emotional feedback resulted from increased activations in the left visual word form area. These findings highlight that decoding who is giving feedback precedes content processing, both in blocked and in randomly alternating situations. Further, in quasi-realistic social contexts, processing of emotional content is selectively amplified. Finally, involvement of semantic language processing structures indicates reintegration of words in a salient context.

In item-method directed forgetting, worse memory performance occurs for to-be-forgotten (TBF) than for to-be-remembered (TBR) items. However, recently TBF items have been found to be recognized more accurately than uninformative (UI) items not associated with any specific task. Here, we compare ERPs elicited by cues signaling the remember or the forget instruction with those elicited by uninformative cues. Participants were presented with a series of complex pictures, each followed by a symbolic TBR, TBF, or UI cue. On a yes-no recognition test, accuracy was higher for TBR than for both TBF and UI items. However, TBF items were recognized more accurately than UI items. ERPs elicited by the TBR cue were larger than ERPs elicited by both TBF and UI cues at the frontal P2, the late frontal negativity, and the late parietal positivity complex. This is consistent with more attention capture, selective rehearsal, and long-term memory encoding of TBR. In contrast, both TBF and UI cues induced a larger frontal N2 than TBR cues. Critically, TBF elicited a larger late right-frontal positivity than both UI and TBR cues and a larger late parietal positivity than UI cues. Moreover, the late right-frontal positivity was correlated with better recognition performance. It may therefore reflect processing orientation rather than inhibition per se. Results suggest that, when compared to UI cues, both TBR and TBF cues are processed actively. Distinct processing is seen at right frontal and centroparietal positive ERPs that may mediate better subsequent recognition of TBF than of UI items.