1. Research Progress on the Role of Ubiquitination in Eye Diseases.
- Author
-
Ma Z, Hao J, Yang Z, Zhang M, Xin J, Bi H, and Guo D
- Subjects
- Humans, Ubiquitin metabolism, Animals, Signal Transduction, Ubiquitination, Eye Diseases metabolism
- Abstract
The occurrence and development of ophthalmic diseases are related to the dysfunction of eye tissues. Ubiquitin is an important form of protein post-translational modification, which plays an essential role in the occurrence and development of diseases through specific modification of target proteins. Ubiquitination governs a variety of intracellular signal transduction processes, including proteasome degradation, DNA damage repair, and cell cycle progression. Studies have found that ubiquitin can play a role in eye diseases such as cataracts, glaucoma, keratopathy, retinopathy, and eye tumors. In this paper, the role of protein ubiquitination in eye diseases was reviewed., (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
- Published
- 2024
- Full Text
- View/download PDF