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The paper considers the methodological aspects of experiments planning on the irradiation of experimental fuel rods of a VVER-SKD reactor and analyzes the features of the concept of sequential irradiation in fast and thermal reactors. It is shown that the 149Sm accumulated at the irradiation in the BOR-60 plays the role of a burnable absorber at the initial stage of irradiation in the reflector cell of the IR-8 reactor. This absorber quickly burns out owing to large absorption cross section and its concentration gradually comes to equilibrium. Burnup of 149Sm leads to a gradual increase in the linear load of the irradiated experimental fuel rod, followed by a decrease and reaching the equilibrium irradiation regime. This effect must be considered when planning the irradiation regime for experimental fuel elements of the VVER-SKD reactor. [ABSTRACT FROM AUTHOR]