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3 results on '"Enrico Chendi"'

1. Procalcitonin in early rule-in/rule-out of sepsis in SIRS patients admitted to a medical ward

Author

Nicola Fiotti, Lorenza Mamolo, Enrico Chendi, Jacopo Lombardi, Daniele Orso, Maurizio Ruscio, Giovanni Fernandes, Andrea Breglia, Giulia Pivetti, Filippo Mearelli, Daniele Peric, Nicola Altamura, Margherita De Nardo, Pierandrea Vinci, Alberto Peretti, Gianni Biolo, Fiotti, Nicola, Mearelli, F, Ruscio, M, Altamura, N, Vinci, Pierandrea, Fernandes, Giovanni, DE NARDO, Margherita, Lombardi, J, Mamolo, Lorenza, Chendi, Enrico, Breglia, Andrea, Peretti, Alberto, Peric, Daniele, Orso, Daniele, Pivetti, Giulia, and Biolo, Gianni

Subjects
Calcitonin, Male, medicine.medical_specialty, Time Factors, Calcitonin Gene-Related Peptide, Clinical Biochemistry, Procalcitonin, Sepsis, Patient Admission, Internal medicine, Intensive care, parasitic diseases, medicine, SIRS, Humans, Medical ward, Protein Precursors, Intensive care medicine, Aged, Aged, 80 and over, procalcitonin, sepsis, SIRS, Receiver operating characteristic, business.industry, Biochemistry (medical), General Medicine, Prognosis, bacterial infections and mycoses, medicine.disease, Sepsis group, Systemic inflammatory response syndrome, Female, business, procalcitonin, hormones, hormone substitutes, and hormone antagonists
Abstract

A relevant amount of patients with clinical suspect of sepsis is admitted and treated in medical wards (MW). These patients have a better prognosis but are older and with more comorbidities compared to those admitted to intensive care units (ICU). Procalcitonin (PCT) is extensively used in emergency departments for the diagnosis of sepsis, but its accuracy in the setting of a MW has not been thoroughly investigated. Predicted low PCT levels also call for the comparison of immunomagnetic-chemiluminescent (L-PCT) and time-resolved amplified cryptate emission (TRACE, K-PCT) technologies, in PCT determination.In 80 patients with systemic inflammatory response syndrome (SIRS) diagnostic criteria and suspect of sepsis newly admitted to a MW, PCT was determined with L- and K-PCT method.Sixty patients were diagnosed as sepsis (20 microbiologically and 40 clinically proven) and 20 with non-infective SIRS. The sepsis group had significantly higher levels of both PCTs, with no differences between the clinically and microbiologically proven subgroups. The areas under ROC curves for L- and K-PCT were 0.72 and 0.78 (pIn MW patients, customized PCT cut-off levels provide better accuracy than customary levels adopted from ICU, and TRACE technology seems to offer a wider analysis range.

Published
2014

2. The Association between Hematological Parameters and Insulin Resistance Is Modified by Body Mass Index – Results from the North-East Italy MoMa Population Study

Author

Gianfranco Guarnieri, Enrico Chendi, Gianluca Gortan Cappellari, Rocco Barazzoni, Michela Zanetti, A. Semolic, Pierandrea Vinci, M. Ius, Roberta Situlin, Barazzoni, Rocco, GORTAN CAPPELLARI, Gianluca, Semolic, ANNA MARIA, Chendi, Enrico, Ius, Mario, Situlin, Roberta, Zanetti, Michela, Vinci, Pierandrea, and Guarnieri, Gianfranco

Subjects
Blood Glucose, Male, obesity, Physiology, lcsh:Medicine, Blood Pressure, Hematocrit, Overweight, Body Mass Index, Hemoglobins, Endocrinology, Medicine and Health Sciences, Homeostasis, lcsh:Science, hematological parameters, obesity, metabolic syndrome, Multidisciplinary, Hematologic Tests, medicine.diagnostic_test, Hematology, Middle Aged, Body Fluids, Cholesterol, Blood, Italy, Physiological Parameters, Population study, Regression Analysis, Female, medicine.symptom, Anatomy, Research Article, Adult, medicine.medical_specialty, Waist, Adolescent, hematological parameters, metabolic syndrome, Young Adult, Insulin resistance, Internal medicine, medicine, Humans, Triglycerides, Aged, Endocrine Physiology, business.industry, Body Weight, lcsh:R, Biology and Life Sciences, nutritional and metabolic diseases, medicine.disease, Obesity, Blood Counts, Erythrocyte Count, lcsh:Q, Metabolic syndrome, Insulin Resistance, business, Body mass index
Abstract

Objective Increments in red blood cell count (RBC), hemoglobin (Hb) and hematocrit (Ht) levels are reportedly associated with higher insulin resistance (IR). Obesity may cause IR, but underlying factors remain incompletely defined, and interactions between obesity, hematological parameters and IR are incompletely understood. We therefore determined whether: 1) BMI and obesity per se are independently associated with higher RBC, hemoglobin and hematocrit; 2) hematological parameters independently predict insulin resistance in obese individuals. Design and Methods We investigated the associations between BMI, hematological parameters and insulin resistance as reflected by homeostasis model assessment (HOMA) in a general population cohort from the North-East Italy MoMa epidemiological study (M/F = 865/971, age = 49±1). Results In all subjects, age-, sex- and smoking-adjusted hematological parameters were positively associated with BMI in linear regression (P

Published
2014

3. Invasive filamentous fungus infection with secondary cerebral vasculitis in a patient with no obvious immune suppression

Author

Giulia Pivetti, Nicola Altamura, Chiara Casarsa, Alessandro Agostino Occhipinti, Gianni Biolo, Giovanni Fernandes, Lorenza Mamolo, Filippo Mearelli, Annalisa Spalluti, Enrico Chendi, F., Mearelli, A., Occhipinti, N., Altamura, G., Fernande, G., Pivetti, E., Chendi, A., Spalluti, L., Mamolo, C., Casarsa, and Biolo, Gianni

Subjects
CNS leukocytoclastic vasculiti, Microbiology (medical), Pathology, medicine.medical_specialty, Central nervous system, Invasive mold infections, Biology, Fever of Unknown Origin, Diagnosis, Differential, Immune system, Fatal Outcome, medicine, Biological fluids, Humans, Fever of unknown origin, Vasculitis, Central Nervous System, CNS leukocytoclastic vasculitis, Invasive Pulmonary Aspergillosis, Fungi, General Medicine, Middle Aged, medicine.disease, Filamentous fungus, medicine.anatomical_structure, Infectious Diseases, Italy, Immunology, Female, Cerebral vasculitis
Abstract

SummaryInvasive mold infections represent an emerging and important diagnostic challenge, especially in immunocompetent patients when microscopy and cultures of the biological fluids remain negative. A central nervous system localization is not common and the clinical presentation is aspecific.

Published
2014
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