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We present 4 cases of cosmetic-related changes on 18F-FDG PET/CT. These cases represent post-treatment changes from facial juvederm injection, silicone injection in the chest wall and gluteal areas, paraffin injection in the gluteal region, and liposuction. Recognition of cosmetic-related changes and their appearance on PET and CT will help to avoid potential false-positive interpretations.

We report the positron emission tomography-computed tomography appearance of Baastrup disease in the L2–L5 interspinous ligament region in a 79-year-old woman with a history of moderately differentiated lobular breast carcinoma. The patient is status post bilateral mastectomies, on tamoxife

We report the PET-CT appearance of a metastasis from a primary colon cancer to the right kidney in an 84-year-old woman with a history of moderately differentiated adenocarcinoma of the cecum. The patient underwent right hemicolectomy and chemotherapy. Restaging PET-CT study, 4 months after her last chemotherapy, demonstrates a hypermetabolic soft-tissue mass in the inferior pole of the right kidney. The patient subsequently had a right partial nephrectomy. The pathology was consistent with metastatic colonic adenocarcinoma. Renal metastasis from primary colon cancer is very rare.

We report F-18 FDG PET-CT appearance of biopsy-proven intramuscular myxoma (IM) in a 69-year-old woman who presented with a left thigh mass. The tumor appears as a well-defined, hypodense mass with thin septation on CT images and mild uptake on PET images. IMs are rare benign myxoid tumors characterized by a paucity of cells, diminished vascularity, and minimal mitotic figures. They most often present as slow-growing, painless, deep-seated intramuscular masses. The mainstay of treatment is surgical resection.

We report the PET-CT appearance of sclerotic bone mimicking active bone metastasis in a 57-year-old woman with right breast cancer and bone and hepatic metastases. Hybrid PET-CT was performed 1 month after completion of surgery and chemoradiation treatment. PET-CT demonstrated hypermetabolic foci in the right pulmonary hilum and liver. Increased hypermetabolic activity in L1 and L3 vertebral bodies was also seen corresponding to sclerotic vertebral bodies on CT study. The activity in L1 and L3 vertebral bodies was not visualized on nonattenuation-corrected images, consistent with an attenuation correction artifact resulting from extensive sclerosis in these regions.