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Your search keyword '"Mohamed AlJaabari"' showing total 2 results
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2 results on '"Mohamed AlJaabari"'

1. Appropriateness of the Direct Oral Anticoagulants Dosing in the Middle East Gulf Region

Author

Leen Oyoun Alsoud, Khalid Almuti, Wasim S El Nekidy, Mohamed AlJaabari, Wael Al Mahmeed, Bassam Atallah, and Zohour Anouassi

Subjects
0301 basic medicine, Male, medicine.medical_specialty, Time Factors, United Arab Emirates, Hemorrhage, Inappropriate Prescribing, 030204 cardiovascular system & hematology, Logistic regression, Risk Assessment, Dabigatran, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, Atrial Fibrillation, medicine, Humans, Drug Dosage Calculations, Dosing, Practice Patterns, Physicians', Stroke, Aged, Retrospective Studies, Pharmacology, Aged, 80 and over, Rivaroxaban, Embolic Stroke, business.industry, Atrial fibrillation, Middle Aged, medicine.disease, Drug Utilization, 030104 developmental biology, Cross-Sectional Studies, Treatment Outcome, Health Care Surveys, Apixaban, Female, Cardiology and Cardiovascular Medicine, business, Major bleeding, medicine.drug, Factor Xa Inhibitors
Abstract

Direct oral anticoagulants (DOACs) have proven efficacy to prevent cardioembolic strokes. Data are scarce about the appropriateness of DOAC dosing in the Middle East. We investigated the prevalence of inappropriate DOAC dosing in the region. A cross-sectional study was conducted at our hospital between April 2015 and February 2019 of patients receiving 1 of the 3 available DOACs. Patients with incomplete data sets, those prescribed DOACs for indications other than atrial fibrillation, on DOACs for

Published
2020

2. Diagnosis of cardiogenic shock without the use of a pulmonary artery catheter

Author

Micaela Iantorno, Julio A. Panza, Amir H. Najafi, Howard A. Cooper, Kambiz Ghafourian, Andre R.M. Paixao, Mohamed Aljaabari, Federico M. Asch, and Daniel A. Canos

Subjects
Male, medicine.medical_specialty, medicine.medical_treatment, Shock, Cardiogenic, Critical Care and Intensive Care Medicine, Intracardiac injection, Internal medicine, medicine, Humans, Myocardial infarction, Prospective Studies, Prospective cohort study, Aged, Retrospective Studies, business.industry, Cardiogenic shock, Pulmonary artery catheter, Hemodynamics, General Medicine, medicine.disease, Shock (circulatory), Cohort, Coronary care unit, Cardiology, Feasibility Studies, Female, medicine.symptom, Cardiology and Cardiovascular Medicine, business
Abstract

Background: Current diagnostic criteria for cardiogenic shock (CS) require the use of a pulmonary artery catheter (PAC), which is time-consuming and may cause complications. A set of simple yet accurate noninvasive diagnostic criteria would be of significant utility. Methods: Candidate components for the Noninvasive Parameters for Assessment of Cardiogenic Shock (N-PACS) criteria were required to be objective, readily available, and noninvasive. Variables encompassing hypotension, hypoperfusion, predisposing conditions, and elevated intracardiac filling pressures were optimized versus a PAC-based standard in a retrospective developmental cohort of 122 patients with acute myocardial infarction (AMI). The finalized criteria were validated in a prospective cohort of coronary care unit patients in whom a PAC was placed for clinical indications. Results: According to invasive criteria, CS was present in 32 of 217 consecutive patients undergoing PAC. Compared to the PAC-based standard, the N-PACS criteria had a sensitivity of 96.9% (95% confidence interval (CI) 82.0–99.8), specificity of 90.8% (95% CI 85.5–94.4), positive predictive value of 64.6% (95% CI 49.4–77.4), negative predictive value of 99.4% (95% CI 96.2–100), positive likelihood ratio of 10.5 (95% CI 6.7–16.7), negative likelihood ratio of 0.03 (95% CI 0.00–0.24), and diagnostic odds ratio of 306.4. Results were similar among patients with and without AMI. Conclusion: A simple, echocardiography-based set of noninvasive diagnostic criteria can be used to accurately diagnose CS.

Published
2014

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