1. Comparison of total endoscopic thyroidectomy with conventional open thyroidectomy for treatment of papillary thyroid cancer: a systematic review and meta-analysis
- Author
-
Chun-Lin Zhao, Peijing Yan, Wen-Jie Jiang, Tiankang Guo, Hongwei Tian, Caiwen Han, Kehu Yang, Wen Tian, Yan-Jun Zhang, Shuangwu Feng, Jia Yang, and Moubo Si
- Subjects
Adult ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,Cochrane Library ,Papillary thyroid cancer ,medicine ,Humans ,Hypocalcaemia ,Thyroid Neoplasms ,Thyroid cancer ,business.industry ,Thyroid ,Thyroidectomy ,Endoscopy ,Middle Aged ,medicine.disease ,Surgery ,medicine.anatomical_structure ,Thyroid Cancer, Papillary ,Meta-analysis ,Female ,business ,Abdominal surgery - Abstract
Despite the fact that thyroid surgery has evolved towards minimal incisions and endoscopic approaches, the role of total endoscopic thyroidectomy (TET) in thyroid cancer has been highly disputed. We performed a systematic review and meta-analyses of peer reviewed studies in order to evaluate the safety and effectiveness of TET compared with conventional open thyroidectomy (COT) in papillary thyroid cancer (PTC). Medical literature databases such as PubMed, Embase, the Cochrane Library, and Web of science were systematically searched for articles that compared TET and COT in PTC treatment from database inception until March 2019. The quality of the studies included in the review was evaluated using the Downs and Black scale using Review Manager software Stata V.13.0 for the meta-analysis. The systematic review and meta-analysis were based on 5664 cases selected from twenty publications. Criteria used to determine surgical completeness included postoperative thyroglobulin (TG) levels, recurrence of the tumor after long-term follow-up. Adverse event and complication rate scores included transient recurrent laryngeal nerve (RLN) palsy, permanent RLN palsy, transient hypocalcaemia, permanent hypocalcaemia, operative time, number of removed lymph nodes, length of hospital stay and patient cosmetic satisfaction. TET was found to be generally equivalent to COT in terms of surgical completeness and adverse event rate, although TET resulted in lower levels of transient hypocalcemia (OR 1.66; p
- Published
- 2020