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Introduction: The aim of the present study was to evaluate the effect of high fiber diet on lipid profile of obese adolescent girls. Methods: This randomized cross over clinical trial was conducted in southern Iran. A total of 56 patients were randomly assigned into two groups. In the first phase, the experiment group had a high fiber diet while the control group consumed their usual diet for 2 months. Then, both groups returned to their usual diet for a month (clean phase) and after that, the diet was replaced for 2 months again (third phase). Serum LDL, HDL, TG and cholesterol were assessed before the intervention, after first phase, clean phase and third phase. Results: The mean reduction of cholesterol, TG, LDL and HDL were significantly lower in high fiber regimens compared to common diet. Conclusion: The results showed that high fiber dietary can significantly reduce lipid profile of obese patients. Consumption of high fiber diet is recommended in order to reduce the adverse effects of obesity.

Introduction: The aim of the present study was to investigate the effectiveness of high-fiber diet on sexual hormones in obese and overweight female adolescents. Methods: This randomized crossover clinical trial was conducted among 56 obese or overweight girls in Shiraz, Iran. All subjects were randomly divided into two groups. A list containing high (25 g/day green leafy vegetables or fresh fruits) and low fiber diets were prepared for case and control groups, respectively. Each group consumed their special diet for two months. After a month of cleanup period, the intended diet was replaced between the two groups. Blood sample of participants were taken in third to fifth day of the spontaneous menstrual cycle. After the end of each step, the serum levels of SHBG, DHEA, estradiol and testosterone were measured. Data was analyzed by SPSS (V.19) using paired International Electronic Journal of Medicine (IEJM) June 2014, Volume 3, Issue 1, Pages: 3-11 ISSN: 2251-8304 www.iejm.net sample t-test and independent t-test. Significant level was considered below 0.05 IRCT ID 2012120811699N1. Results: The results showed that high-fiber diet significantly reduced the serum levels of testosterone, estradiol, and DHEA compared to low fiber diet (P = 0.0001). Nevertheless, the changes of SHBG level were not significant between the two diets (P > 0.05). Conclusions: This study demonstrated that the use of high-fiber diet can decrease the sex hormones in adolescent girls. Consuming a high fiber diet is recommended for obese and overweight patients.