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A new parallel numerical framework CarNum is presented for efficient coupling of mathematical models in multiphysics problems such as computational cardiac electromechanics. This framework is based on open source projects, which provide the core functionality of the platform. Computational cardiac electromechanics requires a complex pipeline of solving different types of ordinary and partial differential equations. Our framework allows one to implement different numerical schemes and provides more control in multiphysics coupling. This paper outlines a concept of the new platform and details of numerical modelling of cardiac electromechanics. First experiments with well-known cardiac electromechanics benchmarks show good agreement with other groups and decent parallel scalability. [ABSTRACT FROM AUTHOR]

The paper discusses a stabilization of a finite element method for the equations of fluid motion in a time-dependent domain. After experimental convergence analysis, the method is applied to simulate a blood flow in the right ventricle of a post-surgery patient with the transposition of the great arteries disorder. The flow domain is reconstructed from a sequence of 4D CT images. The corresponding segmentation and triangulation algorithms are also addressed in brief. [ABSTRACT FROM AUTHOR]

The paper introduces a finite element method for the Navier-Stokes equations of incompressible viscous fluid in a time-dependent domain. The method is based on a quasi-Lagrangian formulation of the problem and handling the geometry in a time-explicit way. We prove that numerical solution satisfies a discrete analogue of the fundamental energy estimate. This stability estimate does not require a CFL time-step restriction. The method is further applied to simulation of a flow in a model of the left ventricle of a human heart, where the ventricle wall dynamics is reconstructed from a sequence of contrast enhanced Computed Tomography images. [ABSTRACT FROM AUTHOR]