6 results on '"Cardoso, Susana M."'
Search Results
2. Salvia Species as Nutraceuticals: Focus on Antioxidant, Antidiabetic and Anti-Obesity Properties.
- Author
-
Afonso, Andrea F., Pereira, Olívia R., and Cardoso, Susana M.
- Subjects
SALVIA ,HYPOGLYCEMIC agents ,ANTIOXIDANTS ,PHENOLIC acids ,SPECIES ,FLAVONOIDS - Abstract
Salvia plants belong to the Lamiaceae family and are recognized as being strongly aromatic, being widely used for different purposes in culinary or traditional medicine. These plants are well recognized as being rich in phenolic acids, flavonoids and terpenic compounds, which exhibit health-beneficial activities, protecting against oxidative and inflammatory-related diseases, such as diabetes and obesity. Because of these properties, phytochemicals from Salvia species have been investigated as health promoting agents, for application in distinct fields. However, the growing demand for natural products with possible uses and applications in industry requires scientific validation studies. This review consists of a compilation of relevant studies with an emphasis on the antioxidant, antidiabetic and anti-obesity properties of phenolic-rich extracts from Salvia plants. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
3. Simultaneous characterization and quantification of phenolic compounds in Thymus x citriodorus using a validated HPLC-UV and ESI- MS combined method
- Author
-
Pereira, Olívia R., Peres, António M., Silva, Artur, Domingues, M.R.M., and Cardoso, Susana M.
- Subjects
Flavonoids ,Electrospray ionization ,Rosmarinic acid ,Luteolin-7-O-a-glucuronide ,Mass spectrometry ,Thymus x citriodorus ,Phenolic compounds - Abstract
Thymus x citriodorus is a Lamiaceae plant extensively cultivated in Mediterranean region and used for centuries in culinary and in traditional medicine. The present work describes the detailed phenolic composition of T. x citriodorus for the first time, the by means of HPLC-DAD, ESI-MS and MSn and nuclear magnetic resonance (NMR) analyses. The ethanolic extract of T. x citriodorus was analyzed by reversed phase HPLC. The method of analysis was also validated concerning its linearity, instrumental and method precision (for repeatability, immediate precision and intermediate precision) and accuracy (absolute recovery study). The technique was combined with electrospray mass spectrometry in order to identify the phenolic compounds and the structure of the main phenolics was also confirmed by NMR analysis. The in-house validated HPLC-DAD method showed good linearity for the tested reference compounds as well as satisfactory repeatability and immediate precision values, for both instrument and method. Furthermore, the satisfactory results of intermediate precision analysis and recovery assays indicated that the chromatographic method could be used to quantify the main phenolic compounds of T. x citriodorus with adequate precision and accuracy. The extract was rich in rosmarinic acid (10.4±0.6 mg/g extract) that is a widespread phenolic acid in Thymus plants, but also in luteolin-7-O--glucuronide (12±2 mg/g extract), that was herein reported in Thymus for the first time. Other novel compounds comprised one eriodictyol dihexoside with O-glycosidic linkages, two eriodictyol-O-monohexosides, one quercetagetin dimethyl ether-O-hexoside, one naringenin-O-hexoside and chrysoeriol-7-β-O-glucoside. Having in mind the health-promoting properties reported in literature for some of the main polyphenols found in T. x citriodorus, we suggest that this plant has a high potential for being used as a functional food.
- Published
- 2013
4. Variation of phenolic constituents of Tunisian Thymus capitatus (L.) Hoff. et Link. populations.
- Author
-
Jaouadi, Rym, Cardoso, Susana M., Silva, Artur M.S., Ben Hadj Yahia, Imen, Boussaid, Mohamed, and Zaouali, Yosr
- Subjects
- *
PHENOLS , *BIOCLIMATOLOGY , *MONOTERPENES , *APIGENIN , *FLAVONOIDS - Abstract
Nine Tunisian Thymus capitatus (L.) Hoff. et Link. populations harvested in six bioclimatic zones extending from the sub humid (550 mm rainfall/year) to the lower arid (96.3 mm rainfall/year), and grown at altitudes ranging from 60 to 600 m were assessed for their phenolic composition. The identification of phenolic compounds was revealed by UHPLC-DAD-ESI/MS n . 11 phenolic compounds including three phenolic acids (rosmarinic acid, salvianolic acid A, salvianolic acid E), three flavanones (hesperidin, eriodictyol and naringenin), two C-glycoside isomers of the flavone apigenin, one flavanol gallocatechine, one flavanonol taxifolin and one phenolic monoterpen (carvacrol) were identified. Differences in phenolic composition among populations, in relationship with altitudes and/or annual rainfall were shown. Higher amounts of total phenols, total flavonoids, rosmarinic acid and carvacrol were detected in samples from the most arid zones (96.3–167 mm rainfall/year) in comparison with populations located in wet lands (450–660 mm rainfall/year). The altitude within or between contiguous climates is a main factor influencing phenol compounds content. The chemical variation among the populations should lead to the selection of plants with high potential in order to use them in health care and food industry. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
5. Phenolic Profiling of Portuguese Propolis by LC-MS Spectrometry: Uncommon Propolis Rich in Flavonoid Glycosides.
- Author
-
Falcão, Soraia I., Vale, Nuno, Gomes, Paula, Domingues, Maria R. M., Freire, Cristina, Cardoso, Susana M., and Vilas‐Boas, Miguel
- Abstract
ABSTRACT Introduction Propolis is a chemically complex resinous substance collected by honeybees ( Apis mellifera) from tree buds, comprising plant exudates, secreted substances from bee metabolism, pollen and waxes. Its chemical composition depends strongly on the plant sources available around the beehive, which have a direct impact in the quality and bioactivity of the propolis. Being as Portugal is a country of botanical diversity, the phenolic characterisation of propolis from the different regions is a priority. Objective Extensive characterisation of the phenolic composition of Portuguese propolis from different continental regions and islands. Method Forty propolis ethanolic extracts were analysed extensively by liquid chromatography with diode-array detection coupled to electrospray ionisation tandem mass spectrometry (LC-DAD-ESI-MS
n ). Results Seventy-six polyphenols were detected in the samples and two groups of propolis were established: the common temperate propolis, which contained the typical poplar phenolic compounds such as flavonoids and their methylated/esterified forms, phenylpropanoid acids and their esters, and an uncommon propolis type with an unusual composition in quercetin and kaempferol glycosides - some of them never described in propolis. Conclusion The method allowed the establishment of the phenolic profile of Portuguese propolis from different geographical locations, and the possibility to use some phenolic compounds, such as kaempferol-dimethylether, as geographical markers. Data suggest that other botanical species in addition to poplar trees can be important sources of resins for Portuguese propolis. Copyright © 2012 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]- Published
- 2013
- Full Text
- View/download PDF
6. Thymus algeriensis Bioss & Reut: Relationship of phenolic compounds composition with in vitro/in vivo antioxidant and antibacterial activity.
- Author
-
Righi, Nadjat, Boumerfeg, Sabah, Fernandes, Pedro A.R., Deghima, Amirouche, Baali, Faiza, Coelho, Elisabete, Cardoso, Susana M., Coimbra, Manuel A., and Baghiani, Abderrahmane
- Subjects
- *
PHENOLS , *THYMUS , *MICROCOCCUS luteus , *SALMONELLA typhimurium , *IRON ions - Abstract
• Phenolic compounds were extracted and purified from Thymus algeriensis. • T. algeriensis showed in vitro and in vivo antioxidant effects. • T. algeriensis purified extracts presented antibacterial effect against 5 bacterial strains. • Antibacterial properties were attributed to rosmarinic acid, kaempferol and eriodictyol derivatives. Thymus algeriensis Bioss & Reut is an Algerian native plant traditionally used for culinary and medicinal purposes. To evaluate the in vivo antioxidant and antimicrobial properties of T. algeriensis , phenolic compounds were extracted using hydromethanolic solutions and administrated to Swiss albinos mice. It was observed that the plasma antioxidant capacity increased, as well as catalase and glutathione levels, whereas malondialdehyde decreased. In vitro assays confirmed that the extract scavenged 2,2-diphenyl-1-picrylhydrazyl, DPPH• (7 µg/mL), chelated (EC 50 : 512 µg/mL) and reduced iron ions (5.3 mM FeSO 4 /g), and inhibited β-carotene bleaching (90% at 2 mg/mL). Antibacterial effects were also observed towards Salmonella typhimurium and Proteus mirabilis. However, the methanolic fraction obtained by reversed solid phase cartridge, showed antibacterial activity against Escherichia coli (MIC = 9.37 mg/mL), Proteus mirabilis (MIC = 4.68 mg/mL), Salmonella typhimurium (MIC = 7.06 mg/mL) , Micrococcus luteus (MIC = 7.03 mg/mL) , and Bacillus cereus (MIC = 2.34 mg/mL). UHPLC-DAD-ESI-MSn analysis showed that these properties could result from rosmarinic acid, caffeoyl rosmaniric acid, and kaempferol and eriodictyol glycoside derivatives. These results pave the way for the understanding of T. algeriensis traditional applications and its use for the development of novel food applications. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.