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Your search keyword '"KD Rakhimov"' showing total 2 results
Start Over Author "KD Rakhimov" Topic flavonoids
2 results on '"KD Rakhimov"'

1. [Hematopoietic resistance to the damaging action of cytostatics in the occurrence of tumor drug resistance].

Author

Rakhimov KD, Vermenichev SM, and Kabiev OK

Subjects
Animals, Drug Evaluation, Preclinical, Drug Resistance, Drug Therapy, Combination, Male, Neoplasm Transplantation, Neoplasms, Experimental drug therapy, Rats, Daunorubicin administration & dosage, Flavonoids administration & dosage, Fluorouracil administration & dosage, Hematopoiesis drug effects, Lymphoma, Non-Hodgkin drug therapy, Melphalan administration & dosage
Published
1981

2. [Mediated action of phytogenic antineoplastic agents on rats with Pliss lymphosarcoma].

Author

Rakhimov KD, Kabiev OK, Kuralasov AK, Togaĭbaeva ZI, and Vermenichev SM

Subjects
Animals, Follicle Stimulating Hormone metabolism, Hydrocortisone blood, Mice, Pituitary Gland metabolism, Polyphenols, Rats, Testosterone blood, Antineoplastic Agents, Phytogenic pharmacology, Flavonoids, Lymphoma, Non-Hodgkin drug therapy, Phenols pharmacology, Polymers pharmacology
Abstract

The action of drugs of plant origin and of alkylating compounds (sarcolysine, prospidin) was accompanied by hormonal changes in rats with inoculated Pliss' lymphosarcoma. After the use of polyphenol plant drugs the secretion of pituitary FSH was inhibited, the blood concentration of testosterone was reduced and the cortisol secretion was substantially increased. The alkylating compounds stimulated the production of FSH, increased the secretion of testosterone, and clearly lowered the cortisol level.

Published
1986

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