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[Display omitted] • BODIPYs are promising fluorophores in classical fluorescent probes in cation recognition. • Chromo-fluorogenic BODIPY probes have been developed for the detection of s , p -, d - or f -element ions. • The action of chemosensors was based on various mechanisms, such as PET, ICT, FRET and others. • The reaction of probe with metal ions results in fluorescent "Off-On" or "On-Off" responses. • Multianalyte BODIPY-probes for the detection of multiple metal ions are tested simultaneously. Content assessment of metal ions (analytes) in solutions, industrial waters and natural objects is one of the most important tasks in biochemistry, medicine, ecology and various industries. To solve this problem, new types of highly sensitive and selective analytical probes are being developed. The most promising areas of analytical control are based on the bright coloristic and fluorescent responses of the complexation reactions of the probe with the analyte. Various classes of fluorescent dyes have been successfully used to obtain such probes. Among them, BODIPY fluorophores are of particular interest due to the manifestation of intense spectral-luminescent and other practically significant properties. The review focuses on advances in the development of chromo-fluorogenic BODIPY probes containing various receptor fragments selective for cations of individual s- , p -, d - or f -elements. Probes work by various mechanisms, such as photo induced electron transfer (PET), internal charge transfer (ICT), fluorescence resonance energy transfer (FRET) and others. Ultimately, the reaction of the probe with the analyte results in significant fluorescent "Off-On" or "On-Off" responses. The review contains several sections in which fluorescent BODIPY probes were divided into groups of detectable s- , p -, d - and f -elements. The spectral properties of BODIPY probes, their chromo-fluorogenic, including ratiometric, responses when binding to the analyte being determined in solutions, the binding efficiency, as well as the selectivity of determining the analyte are discussed. In addition, in many cases the possibility of practical use of probes for the analysis of metal ions in aqueous, aqueous-organic media, and cells was shown. [ABSTRACT FROM AUTHOR]

This microreview covers the currently available data about the synthesis and practically valuable spectral and luminescence properties of tetraaryl-substituted aza-BODIPY dyes. [ABSTRACT FROM AUTHOR]

Fluorescent dyes absorbing and emitting in the visible and near-IR regions are promising for the development of fluorescent probes for labeling and bio-visualization of body cells. The ability to absorb and emit in the long-wavelength region increases the efficiency of recording the spectral signals of the probes due to the higher permeability of the skin layers. Compared to other fluorescent dyes, BODIPYs are attractive due to their excellent photophysical properties–narrow absorption and emission, intense fluorescence, simple signal modulation for the practical applications. As part of conjugates with biomolecules, BODIPY could act as a biomarker, but as therapeutic agent, which allows solving several problems at once-labeling or bioimaging and treatment based on the suppression of pathogenic microflora and cancer cells, which provides a huge potential for practical application of BODIPY conjugates in medicine. The review is devoted to the discussion of the recent, promising directions of BODIPY application in the field of conjugation with biomolecules. The first direction is associated with the development of BODIPY conjugates with drugs, including compounds of platinum, paclitaxel, chlorambucil, isoxazole, capsaicin, etc. The second direction is devoted to the labeling of vitamins, hormones, lipids, and other biomolecules to control the processes of their transport, localization in target cells, and metabolism. Within the framework of the third direction, the problem of obtaining functional optically active materials by conjugating BODIPY with other colored and fluorescent particles, in particular, phthalocyanines, is being solved. [ABSTRACT FROM AUTHOR]