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[Display omitted] • A new 1,3 propane dithiol substituted naphthalimide based "turn-on" fluorescence sensor for detection of Hg2+ was developed. • TNA was also spiked to detect Hg2+ ion in various environmental water samples. • The present sensor probe was successfully utilized to detect Hg2+ ion in biological cell using fluorescence bio-imaging. • The obtained detection limit (LOD) for Hg2+ is found to be 3.3 nM. This work represents a napthalimide derived fluorescent sensor for the selective and sensitive detection of Hg2+ utilizing the thioacetal group as a sensing unit. The immense selectivity of 6-(4-(1,3-dithian-2-yl)phenyl)-2-(2-morpholinoethyl)-1H benzo[de]isoquinoline-1,3(2H)-dione (TNA) has been investigated in ACN: H 2 O (8:2) system and the rapid response towards Hg2+ was found to be 10 s. In detecting Hg2+, TNC exhibits a blue emission (λ max = 429 nm), and the limit of detection was evaluated to be 3.3 nM. The sensing mechanism describes that the Hg2+ induces colorless to blue fluorescence-enhancement at 429 nm originated from the de-thiolation of an aldehyde. This stimulates the ICT process of TNA which resulted in the enhancement in fluorescence. Moreover, the sensor ligand was effectively applied for imaging Hg2+ in E-coli live cells. [ABSTRACT FROM AUTHOR]

[Display omitted] • A new naphthalimide based "turn-on" fluorescent probe for detection of H 2 S has been designed and synthesised. • Probe NPN-N 3 exhibits very high selectivity and sensitivity towards H 2 S. The obtained Limit of Detection (LOD) for H 2 S is found to be 1.2 μM. • Probe NPN-N 3 can successfully detect H 2 S levels in wine, beer and various environmental water samples. • Probe NPN-N 3 was successfully implemented in bioimaging application. A novel fluorescent sensor based on intramolecular charge transfer (ICT) for detecting the H 2 S ion has been successfully designed and developed. The H 2 S amount was determined using a sensor probe of 6-azido-2-(pyridin-2-ylmethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione (NPN-N 3) with high selectivity. The fluorescence intensity ratio of NPN-N 3 was shown to be linearly related to the concentration of H 2 S, with a LOD of 1.2 μM. Besides that, there was an apparent fluorescent colour changes from colorless to green. Fluorescence bio-imaging with various emission channels could be used with the current sensor probe to detect H 2 S ions in living cells. The real-time application of H 2 S was proved by test strip experiments. [ABSTRACT FROM AUTHOR]

[Display omitted] • A new and economically viable naphthalimide based "turn-on" fluorescent probe for detection of H 2 S has been designed and synthesised. • Probe NAP-N 3 exhibit very high selectivity and sensitivity towards H 2 S. The obtained limit of detection (LOD) for H 2 S is found to be 1.5 μM. • Probe NAP-N 3 can successfully detect H 2 S levels in wine, beer, and various environmental water samples. • Probe NAP-N 3 was successfully implemented in bioimaging application. The selective detection of hydrogen sulfide (H 2 S) in environmental and living systems has gained substantial attention in recent years. However, the identification of rapid and highly selective probes for the detection of H 2 S remains an elusive goal. This article presents the design and synthesis of a fluorescent "turn-on" probe based on the 1,8-naphthalimide framework (NAM-N 3) to achieve this goal. H 2 S triggered reduction of NAM-N 3 resulted in a remarkable ratiometric absorption enhancement alongside fluorescent "turn-on" response in the green region. The detection properties of NAM-N 3 towards H 2 S were satisfactorily studied through fluorescence, UV–vis, 1H NMR, and mass analysis. The detection response was rapid, and the limit of detection (LOD) was calculated as 1.5 μM. The practical applicability of the probe was tested on various platforms. [ABSTRACT FROM AUTHOR]

[Display omitted] • A phosphinine containing sensor for the ratiometric fluorescent detection of Hg2+ has been developed. • Paper kit-based recognition was established. • The sensing mechanism of Hg2+ was clearly explained by 1H NMR and HPLC titrations. • The sensor could be utilized to detect Hg2+ in living cells. Due to its great toxicity to the bio-aquatic environment, developing highly selective and sensitive probes for the detection of mercury ions in solutions as well as in living cells is a major problem. To detect Hg2+ ions in organic semi-aqueous solutions, we created a fluorescent probe called 4-(1, 3-dithian-2-yl)-1,1-diphenyl- λ 5-phosphinine-2,6-dicarbonitrile (DDPD) with optical behaviour. Through the Hg2+-promoted deprotection process of thioacetals, which was followed by considerable changes in fluorescence colour and spectral pattern, the probe DDPD selectively detected Hg2+ ions in a broad pH range with a detection limit of 56 nM. Specifically, DDPD can be used to qualitatively identify Hg2+ ions using test strips made of Whatman filter paper and also in HeLa cells it can identify Hg2+ ions and image them using fluorescent microscopy. [ABSTRACT FROM AUTHOR]

[Display omitted] • A new piperazine-based phenanthridine sensor probe was synthesized and characterized. • The fluorescence revealed that 5a is a superior selective sensor towards Th4+ ion in the presence of other competitive metal cations. • The kinetic study realized the detection of Th4+ ions in 15 s. • The limit of detection value is as low as 2.76 nM for Th4+ ion. • Probe 5a has been investigated for test paper strips applications as well as Th4+ ion analysis in real water samples. A benzhydrylpiperazine-based phenanthridine (5a) moiety has been developed as a ratiometric fluorescence and colorimetric probe for the detection of Th4+ ion. After the addition of Th4+ ion, probe 5a was immediately color-altered from blue to yellow fluorescence with an emission maximum at 560 nm. Probe 5a showed superior selectivity and sensitivity towards Th4+ ions over the other competitive metal ions. This sensor probe exhibited a lower detection limit (2.76 nM). Then through the 1H NMR titration experiment, it was confirmed that the benzhydrylpiperazine moiety of 5a was chelated with Th4+ ion. However, probe 5a was utilized for the detection of Th4+ ion in real water samples and monazite sand. Most importantly, the application of this sensor probe 5a for the recognition of Th4+ ion in E. coli cells had been successful. [ABSTRACT FROM AUTHOR]