1. Thoracic SMARCA4-Deficient Undifferentiated Tumor Mimicking a Pleural Mesothelioma on 18 F-FDG PET/CT.
- Author
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Chen X, Chen G, Li Q, and Fu Z
- Subjects
- Humans, Female, Aged, Diagnosis, Differential, Thoracic Neoplasms diagnostic imaging, Tomography, X-Ray Computed, Multimodal Imaging, Fluorodeoxyglucose F18, Positron Emission Tomography Computed Tomography, Mesothelioma diagnostic imaging, Pleural Neoplasms diagnostic imaging, Transcription Factors genetics, DNA Helicases genetics, Nuclear Proteins genetics, Nuclear Proteins deficiency
- Abstract
Abstract: A 72-year-old woman, who was a nonsmoker, presented with chest distress persisting for over 10 days. Plain chest CT revealed thickening of the left pleura accompanied by hydrothorax. Subsequent 18 F-FDG PET/CT showed irregular thickening involving the visceral, parietal, and interlobular pleura on the left side, with diffuse high avidity of 18 F-FDG. The left pleural mesothelioma was suspected initially, but pathological examination from biopsied specimen later confirmed a thoracic SMARCA4-deficient undifferentiated tumor., Competing Interests: Conflicts of interest and sources of funding: none declared., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2024
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