1. Anticholinergic and antioxidant activities of avocado (Folium perseae) leaves - phytochemical content by LC-MS/MS analysis
- Author
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Ekrem Köksal, Hulya Akincioglu, Leyla Polat Kose, Saleh Alwasel, Lokman Durmaz, Zeynebe Bingol, İlhami Gülçin, Ahmet C. Gören, Ruya Kaya, Belirlenecek, and GÖREN, AHMET CEYHAN
- Subjects
Antioxidant ,In-Vitro Antioxidant ,medicine.drug_class ,Kose L. P. , Bingol Z., Kaya R., GÖREN A. C. , Akincioglu H., DURMAZ L., KÖKSAL E., Alwasel S. H. , GÜLÇİN İ., -Anticholinergic and antioxidant activities of avocado (Folium perseae) leaves - phytochemical content by LC-MS/MS analysis-, INTERNATIONAL JOURNAL OF FOOD PROPERTIES, cilt.23, ss.878-893, 2020 ,medicine.medical_treatment ,antioxidant activity ,lcsh:TX341-641 ,Inhibition Profiles ,Polyphenol Contents ,Folium perseae ,Lc ms ms ,Anticholinergic ,medicine ,Avocado ,Folium of Descartes ,Butyrylcholinesterase ,radical scavenging ,Traditional medicine ,lcsh:TP368-456 ,Chemistry ,Potent Carbonic-Anhydrase ,food and beverages ,acetylcholinesterase ,1st Synthesis ,Radical Scavenging Activity ,Antioxidant capacity ,lcsh:Food processing and manufacture ,Phytochemical ,Bromophenols ,Antiradical Activities ,lcsh:Nutrition. Foods and food supply ,Food Science - Abstract
In the first stage of the manuscript, we aimed to examine antioxidant capacity and anticholinergic properties of avocado (Folium perseae) leaves. Avocado leaf was extracted by water (WEFP) and ethyl alcohol (EEFP) and antioxidant activity was determined using by several antioxidant assays including DPPHGreek ano teleia and ABTS(center dot+)radical scavenging assays, Cu2+-Cu(+)reducing, Fe3+-Fe(2+)reducing, and FRAP reducing activities. Avocado leaf extracts demonstrated antioxidant activity and anticholinergic activities, while alpha-tocopherol, BHT, trolox, and BHA were used as positive antioxidant controls. In the second part of this study, the inhibition effects of WEFP and EEFP were valuated against acetylcholinesterase and butyrylcholinesterase enzymes, which catalyze the breakdown of choline esters (i.e. neurotransmitters). This study obviously showed that avocado leaf extracts had effective antioxidant, antiradical, and anticholinergic influences., King Saud University, Saudi Arabia [RSP-2019/59], S. Alwasel would like to extend his sincere appreciation to the Researchers Supporting Project (RSP-2019/59), King Saud University, Saudi Arabia, for support. No conflict of interest associated with this work.
- Published
- 2020