1. Thermodynamics of switching in multistable non-equilibrium systems
- Author
-
Robert G. Endres, Jacob Cook, and Biotechnology and Biological Sciences Research Council (BBSRC)
- Subjects
02 Physical Sciences ,Chemical Physics ,Statistical Mechanics (cond-mat.stat-mech) ,010304 chemical physics ,Entropy production ,FOS: Physical sciences ,General Physics and Astronomy ,Thermodynamics ,010402 general chemistry ,01 natural sciences ,09 Engineering ,0104 chemical sciences ,Nonlinear system ,Biological Physics (physics.bio-ph) ,0103 physical sciences ,Physics - Biological Physics ,Physical and Theoretical Chemistry ,03 Chemical Sciences ,Condensed Matter - Statistical Mechanics ,Noise strength - Abstract
Multistable non-equilibrium systems are abundant outcomes of nonlinear dynamics with feedback but still relatively little is known about what determines the stability of the steady states and their switching rates in terms of entropy and entropy production. Here, we will link fluctuation theorems for the entropy production along trajectories with the action obtainable from the Freidlin--Wentzell theorem to elucidate the thermodynamics of switching between states in the large volume limit of multistable systems. We find that the entropy production at steady state plays no role, but the entropy production during switching is key. Steady-state entropy and diffusive noise strength can be neglected in this limit. The relevance to biology, ecological, and climate models is apparent., 8 pages, 3 figures
- Published
- 2020