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The bachelor thesis presents a comparison of mass loss and moisture content of samples from Norway spruce (Picea abies), that were dried by different proces -- natural air drying and microwave drying.. All of samples were degraded by wood-destroying brown rot fungi -- Serpula lacrymans -- in the range from two to twelve weeks. Measurements were made every fourteen days. At the end of experiment several samples were selected for the production of microscopical slides, on which one can observe the progressive degradation of the cell wall of spruce wood. The measurements show that the use of microwaves radiation output of 2 kW has a minimal influence on the fungi spread rate and wood degradation. The highest difference was measured after eight weeks, the average mass loss of microwave dried samples was 25.41%, while in natural dried samples only 23.54%.