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The present state-of-the-art in chiral capillary gas chromatography (GC) is reviewed in this article. The article provide a short historical overview of phase development followed by a comparison of GC [...]

This article discusses supercritical fluid chromatography (SFC) and its advances in theory, instrumentation, and novel applications, referencing the study "Modern Supercritical Fluid Chromatography -- Possibilities and Pitfalls" published in March 1, 2015 at www.chromatographyonline.com. Topics of the study include the advantages of SFC over traditional high performance liquid chromatography (HPLC) and why SFC is considered much more complex than liquid chromatography (LC).

Discusses the similarity between the solid-phase microextraction technique and single-drop microextraction (SDME) method for headspace sampling for gas chromatographic analysis. Classes of residual solvents monitored in pharmaceutical formulations; Headspace SDME results using N-methyl-pyrrolidone, an International Conference on Harmonization Class 2 solvent; Factors that have been considered for the SDME method.

Discusses the in-tube solid-phase microextraction (SPME) and on-line coupling with high-resolution gas chromatography (GC). Description of the concept for SPME; Analysis of aqueous samples using in-tube SPME-GC; Information on the difference between in-tube SPME and fiber SPME syringe-liquid chromatography.

A glossary of terms related to chromatography is presented.

Information about the 65th Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy (Pittcon) conference and exposition that was held in Chicago, Illinois on March 2 to 6, 2014 is presented. Topics include on the provided information for separation consumables and accessory products displayed during the conference for the chromatography industry. It also mentions that the products have correlations to research, development and application activity in the separation sciences.

The article discusses the new sorbent materials which have the potential to help in solving specific chromatography laboratory problems. It states the increased application of solid-phase microextraction (SPME), solid-phase extraction (SPE), and stir-bar sorbent extraction (SBSE) in diverse markets. In addition, it cites molecularly imprinted polymers (MIPs) as one of the selective phases used in SPE such as in areas where selective recognition is needed.

The article offers information on gas chromatography-mass spectrometry (GC-MS) and GC-MS-MS systems' surface activity surface activity and GC flow path. It mentions that the GC flow path is every component of the system, where injected sample touches. It reports that reactive analysis of injected sample will never be detected if sample lost on reactive sites of surface in the GC flow path. It presents a table GC flow path component reactivity risk with a sample on a typical GC system.

In this article, importance of various sample preparation techniques for effective determination of components through chromatography methods is discussed. An overview of tandem mass spectrometric technique for preparation of sample to be detected through gas chromatography and high performance liquid chromatography is investigated. It highlights that selectivity factor in chromatographic parameters to retain analytes can be enhanced through effective sample preparation techniques.

The present state-of-the- art in chiral capillary gas chromatography (GC) is reviewed by guest columnist, Tom Beesley, one of the pioneers in chiral separations. He will provide a short historical overview of phase development followed by comparison of GC and high performance liquid chromatography (HPLC) chiral separations. After a short discussion of mechanisms of the most popular cyclodextrin phases, he then provides practical recommendations on how to select the best stationary phase and then how to use it to optimize chiral GC separations. Examples of elution order reversal of racemates, injection of large volumes of diluted sample using retention gaps, and other applications are also provided. [ABSTRACT FROM AUTHOR]

The article focuses on the use of method translation in liquid chromatography. It discusses the high performance liquid chromatography (HPLC) and compares it with the gas chromatography (GC) method translation. It talks about the need to set performance goals to determine if an isocratic method is ready for method translation. Also discussed is the use of gradient elution to analyze complex samples, reducing analysis time, increasing peak capacity and increasing sensitivity.

The article discusses the effectiveness of hydrogen carrier gas. It mentions that in gas chromatography (GC) and GC-mass spectrometry (MS) applications, hydrogen carrier gas can be an effective replacement for helium. It emphasizes that hydrogen provides a better combination of speed and efficiency over a wide range of linear velocities. It further suggests that caution is important during the laboratory process.

The article focuses on the ionic liquids (ILs) as substances that play an important role in gas chromatography (GC) column technology in the U.S. ILs are solvents that is made up of ions and are substances that are pure salts with melting points below 100°centigrade. ILs' varied viscosity, thermal stabilities and its unique solvent properties make them exceptional stationary phases. The characteristics of ILs are useful for multidimensional separations processes.

The article presents the Part II on the discussions regarding the "59th Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy" in New Orleans, Louisiana. The Pittcon remains the most important yearly international analytical exhibition wherein companies introduces their latest instruments, instruments accessories, software, columns, sample preparation and other consumable products. Gas chromatography (GC) is considered to be a relatively mature separation technique.

The article highlights the practical guidelines in the care and maintenance of capillary gas chromatography columns. It discusses the issues surrounding avoiding column breakage, stationary phase damage, and column contamination. Prolonging the life of a column by keeping an oxygen-free system, providing a cleaner sample, and not exceeding the upper temperature limit of the stationary phase are highlighted in this article.

It might be somewhat audacious To claim that some methods in GC×GC can be called nonclassical-with the relatively brief history GC×GC (about 15 years) one might argue that there has been insufficient time to establish a suite of classical methods. However, it is possible to describe a general approach to GC×GC that held a predominant position in the years up to the early 2000s. This brief review will introduce the GC×GC technique and its advantages, which primarily lie in the area of increased separation power for volatile chemical analysis. It will then outline some recent applications that are departures from the classically implemented method such as offering approaches to increasing the speed of analysis, the use of quite different operating conditions to achieve specific chromatographic goals, and the benefits and contrasting results that are obtained when ‘inverted’ column phase Arrangements are employed. [ABSTRACT FROM AUTHOR]

The article traces the history of gas chromatography. It was first envisioned by A.J.P. Martin in 1948 and enjoyed a wider use in 1953. These early efforts employed packed columns, in which resistance to gas flow limits practical column lengths and the total number of attainable theoretical plates. The invention of the open tubular column alleviated the restriction, and patents on open tubular columns were rigorously enforced. Hansjuerg Jaeggi explored the possibilities of commercializing column production, and only by exploiting a unique provision in Swiss law were inventors able to force the issuance of a license from Perkin Elmer.

Addresses some of the capillary column basics by investigating a standard test mixture. Observation of some of the chromatographic effects that can affect peak response, peak shape and column bleed; Analysis of variables which affects gas chromatography resolutions.

Focuses on the advantages of headspace sampling for gas chromatographic analysis in North America. Elimination of many interferences from the sample matrix; Cost effectiveness of solid-phase microextraction; Similarity between headspace single-drop microextraction and traditional headspace sampling.

Examines trends in gas chromatography (GC) column usage based on user surveys in the U.S. Users' primary fields of work and application areas; Major markets in which GC is used; Decline in the use of packed columns in GC applications; Importance of the selection of appropriate stationary and mobile phases in High Performance Liquid Chromatography; Column problems.

Focuses on the fused-silica capillary columns for gas chromatography. Impact of capillary quality problems on columns; Methods on the improvement of quality and performance of the capillaries used in science columns; Technology of fiber optics and microelectronics in relation to fused-silica capillaries.

Presents information on the validation of an in-tube solid phase microextraction device (SPME) for the analysis of organic contaminants in water. Information on the function of SPME; Process of dynamic extraction technique; Comparison of classic SPME with on-line in-tube SPME system.