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1. Contents, Vol. 24, 1982

Author

M. Dubrasquet, Eileen Friedman, G. Anzidei, R. Noriega, R. Farini, Justrabo E, Giampaolo Angelini, R. Naccarato, J. Elashoff, Antonio Francavilla, I.S. Menzies, Nils-Olivier Olsson, W. Niebel, Fabio Vianello, G. Kay, Ludovico A. Scuro, F. Doronzo, Martin Lipkin, Joan M. Braganza, M. Fujita, P Hine, Gabriele Mazzacca, M. I. Grossman, G. Cavallini, Thérèse Lehy, Jean-François Jeannin, G. Parrilli, L. Augenlicht, Monique Martin, Gaetano Capuano, R. Cotumaccio, O. Albano, R. Bonnafous, Gabriele Budillon, Anne Caignard, Manfred V. Singer, C. Stock-Damge, Serge Bonfils, J. Catala, M. Usugane, G. Massi, P. Brazeau, R. Palmer, Francis Raul, J.F. Grenier, M. Doffoel, F. Di Mario, Robert Michiels, and G. Bruscalupi

Subjects
Gastroenterology
Published
1982
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2. Contents, Vol. 29, 1984

Author

W. Humbert, Manuela Minguzzi, Klaus E. Gyr, Massimo Campieri, Stephen R. Bloom, V. Keim, R. Noriega, Juan J. Alberti-Flor, G. Rohr, C. Stock-Damge, A. Pousse, Sidney J. Winawer, Zouheir M. Habbal, George A. Stalder, P. Casanova, Lucio Gullo, Derek P. Jewell, Gabriele Bazzocchi, Sarah L. Dunn, Malik Massad, R. D’Oliveira, Luigi Bolondi, G. Labò, Giorgio Assuero Lanfranchi, Jonathan M. Rhodes, Eva von Alvensleben, Giuseppe Labò, F.J. Haberich, E. Lhoste, Jane G. Mills, Guido A. Zäch, Eugene R. Schiff, Eleanor E. Deschner, F. Bertoni, Brad M. Dworkin, Robert B. Fath, W S Selby, Robert G. Newcombe, Corrado Brignola, Marc Aprahamian, Marwan Iskandarani, H.G. Stöckert, Lennox J. Jeffers, M K Bennett, John F. Mayberry, P. Priori, Camille F. Nassar, and J.F. Grenier

Subjects
Gastroenterology
Published
1984
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3. Subject Index, Vol. 24, 1982

Author

Fabio Vianello, Gabriele Mazzacca, Manfred V. Singer, C. Stock-Damge, R. Farini, G. Massi, Eileen Friedman, Martin Lipkin, Anne Caignard, P. Brazeau, R. Noriega, R. Palmer, O. Albano, Giampaolo Angelini, Serge Bonfils, G. Cavallini, R. Cotumaccio, R. Bonnafous, M. Usugane, G. Anzidei, Joan M. Braganza, J. Catala, M. I. Grossman, M. Fujita, Jean-François Jeannin, G. Bruscalupi, J.F. Grenier, Justrabo E, J. Elashoff, Francis Raul, Gabriele Budillon, M. Dubrasquet, Thérèse Lehy, W. Niebel, F. Doronzo, G. Parrilli, P Hine, G. Kay, Gaetano Capuano, Nils-Olivier Olsson, L. Augenlicht, M. Doffoel, F. Di Mario, Robert Michiels, Monique Martin, R. Naccarato, Antonio Francavilla, I.S. Menzies, and Ludovico A. Scuro

Subjects
Index (economics), Statistics, Gastroenterology, Subject (documents), Mathematics
Published
1982
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4. Subject Index, Vol. 29, 1984

Author

Corrado Brignola, Marc Aprahamian, Marwan Iskandarani, Juan J. Alberti-Flor, G. Labò, V. Keim, Robert B. Fath, W. Humbert, Eva von Alvensleben, A. Pousse, Giorgio Assuero Lanfranchi, Eugene R. Schiff, Zouheir M. Habbal, P. Priori, Camille F. Nassar, Sarah L. Dunn, Sidney J. Winawer, P. Casanova, G. Rohr, H.G. Stöckert, Gabriele Bazzocchi, Malik Massad, C. Stock-Damge, George A. Stalder, J.F. Grenier, Derek P. Jewell, R. D’Oliveira, Luigi Bolondi, Manuela Minguzzi, Lucio Gullo, Jane G. Mills, Guido A. Zäch, M K Bennett, Lennox J. Jeffers, John F. Mayberry, Stephen R. Bloom, Giuseppe Labò, F.J. Haberich, E. Lhoste, R. Noriega, Klaus E. Gyr, W S Selby, Robert G. Newcombe, F. Bertoni, Brad M. Dworkin, Eleanor E. Deschner, Jonathan M. Rhodes, and Massimo Campieri

Subjects
Index (economics), Statistics, Gastroenterology, Subject (documents), Mathematics
Published
1984
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5. Effect of chronic alcohol administration on liver morphology and on brush border membrane enzymes after jejunoileal bypass operation in rat

Author

R. Noriega, Francis Raul, M. Doffoel, J.F. Grenier, and C. Stock-Damge

Subjects
medicine.medical_specialty, Brush border, medicine.medical_treatment, Jejunoileal bypass, Ileum, Stimulation, Aminopeptidases, Sucrase, Jejunum, chemistry.chemical_compound, Random Allocation, Internal medicine, medicine, Animals, Obesity, Ethanol, Microvilli, business.industry, Cell Membrane, Gastroenterology, Rats, Inbred Strains, beta-Galactosidase, Disaccharidase, Rats, medicine.anatomical_structure, Endocrinology, chemistry, Liver, business
Abstract

To determine whether jejunoileal bypass operation and alcohol administration exerted a synergistic effect on the activities of brush border membrane enzymes and on liver morphology, adult rats where submitted either to sham operation or to jejunoileal bypass operation. 2 weeks after operation the rats received a 15% solution of ethanol during a period of 4 weeks, controls received water. In the sham-operated rats, alcohol provoked stimulation of the disaccharidase activities in the proximal jejunum but had no effect on these activities in the ileum. Bypass operation alone induced a significant increase in sucrase activity in the functioning ileum but had no effect on the jejunal disaccharidase activities. Alcohol administered after bypass provoked a further increase in ileal brush border sucrase activity. The increase of the brush border enzyme specific activities in the excluded loop resulted from the important protein loss observed in this segment. Alcohol alone or bypass operation by itself had little effect on liver morphology. In contrast, when associated they induced extensive accumulation of fat droplets in the hepatocytes. Since alcohol is frequently associated with the diet in man, alcohol should be considered as an important contributing factor to intestinal enzyme adaptation and liver dysfunction after jejunoileal bypass operation.

Published
1982

6. Pancreatic hyperplasia after small bowel resection in the rat: dissociation from endogenous gastrin levels

Author

Marc Aprahamian, J.F. Grenier, C. Stock-Damge, W. Humbert, A. Pousse, R. Noriega, E. Lhoste, Unit 61, Biophysiopathology of the Intestine, and Institut National de la Santé et de la Recherche Médicale (INSERM)

Subjects
ntestine, Male, Short Bowel Syndrome, medicine.medical_specialty, Pancreatic hyperplasia, [SDV]Life Sciences [q-bio], medicine.medical_treatment, Peptide hormone, Biology, Pyloroplasty, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Malabsorption Syndromes, Gastrectomy, Internal medicine, gastrin, Gastrins, Intestine, Small, medicine, Animals, rat, resection, Pancreas, Vagotomy, Proximal Gastric, Pylorus, 030304 developmental biology, Gastrin, 0303 health sciences, Hyperplasia, digestive, oral, and skin physiology, Body Weight, Proteins, Rats, Inbred Strains, DNA, Organ Size, medicine.disease, Vagotomy, Small intestine, Rats, medicine.anatomical_structure, Endocrinology, 030211 gastroenterology & hepatology
Abstract

International audience; Extensive small bowel resection produces pancreatic hyperplasia and increases plasma gastrin levels in the rat. Because gastrin is known as a trophic factor for the exocrine pancreas, we studied the effect of endogenous variations of gastrin induced by different gastric operations on the rat pancreas in both resected and transected animals. Vagotomy increased plasma gastrin level while antrectomy decreased it; pyloroplasty was without any effect. These gastric operations enhanced slightly but not significantly the pancreatic weight, its protein and DNA content. A 90% jejunoileal resection alone increased markedly these parameters while mitotic figures appeared in acinar cells. Pyloroplasty, vagotomy and antrectomy did not modify the changes induced by intestinal resection itself except the level of protein. These findings suggest that hypergastrinemia produced by intestinal resection is not responsible for pancreatic hyperplasia.

Published
1984
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