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The present study was conducted in the National Sheep Research Station in Elhuda, Sudan where the sheep flocks are kept for scientific research purposes. The aim of the study is to evaluate two systems of sheep productivity namely: the prevailing annual single lamb cropping (sheer-sedentary) and induced three lamb cropping per two years to which feed supplementation is provided (improved – sedentary). Three subtypes: Shugor, Dubasi and Watish in Sudan Desert sheep were used for a three –lamp crops, per two years, in addition to feed supplementation, to represent an improved-sedentary system, (B) against a sheer sedentary (A), that represents an annual single-lamp-crop system. The improved sedentary was associated with reductions in the overall average values of the traits: ewes losses (1.95 vs 3.09%), ewe barrenness (17.30 vs 28.67%) and lambing interval (257.97 vs 353.50 days ), whereas it enhanced lambing rate (82.73 vs72.67 %), litter size at weaning measured: as lambs weaned per ewes exposed for breeding (1.01 vs 0.67) and as lambs weaned per ewes that actually lambed (1.12 vs 0.93) improved adjusted lamb weaning weight per ewe at 60 days of lamb age (13.62 vs 10.58 kg) , increased lamb survival rate (93.91 vs 75.63%) and eventually promoted productivity index (18.36 vs 5.25kg) of lambs weaned per ewe per year. These overall average values were calculated out of the mean values of the measured traits shown in tables (1 and 2) of the text. Furthermore, the comparison between the three subtype sheep groups for their performance as affected by the improved sedentary against the sheer - sedentary revealed similar trends of response as above, that culminated in the Shugor subtype having the greatest productivity index mean value (20.82 kg) as subsequently compared with that of either the subtype Dubasi (17.56 kg) or the Watish subtype (16.70 kg). It is concluded that these results do encourage the adoption and projection on the improved-sedentary system, specially, under the surroundings of irrigated agriculture land use to provide extra income to the welfare of the farmer.

This study was carried out at the National Sheep Research Station in Elhuda, Sudan to investigate the situation of female sheep conditions while in gestation and to consult some aspects associated to pregnancy parameters and others on live weight were collected, processed and statistically tested in addition to variability consideration. Thus, live weight changes its variability and some relationships for certain reproductive traits in the Shugor and Dubasi subtypes of Sudanese Desert sheep ewes were studied from mating events to the immediate postpartum date. The overall live weight changes during this period resulted in an increase of 22.8 and 27.6% in the live weight of either of these two ewe groups ,respectively, but with an overall greater in live weight variability within the Shugor as contrasted with that within their contemporary Dubasi ewe group (11.33vs 8.27%, CV), having periodic mean value which ranges from 10.70 -13.5% CV and 7.2 – 8.5% CV, respectively, for the Shugor and Dubasi ewe groups. The combined contribution of the foetal lamb weights, foetal placenta fluids weights composed 20.0% for the Shugor and 17.9% for the Dubasi of the breeding (mating) live weight of each while the weight of the lamb at birth and that of the associated placenta had mean values of 11.1 ±0.06% and 1.23 ± 0.06, respectively, of the Shugor pre-partum ewe live weight but the corresponding mean proportional values in the Dubasi group were 9.48 ± 0.49% and 1.20 ±0.08 % .The regression of gestation length, post-partum ewe live weight and lamb birth weight had mean values of + 0.37 , + 0.71 and 0.002 as related to the breeding (mating) ewe live weight of the Shugor whereas the corresponding regression values in the Dubasi ewes were +0.03 ,+ 0.67 and + 0.03. None of these contrasting parameter values was significantly different in the two subtype groups. Similarly, the regression values of the placenta weight on the lamb birth weight were not significantly different, respecttively, - 0.02 and + 0.032 in the Shugor and Dubasi ewe groups. It is concluded that live weights variations in breeding females should be made manageable to their least possible to allow for more solid data, on the female and its offspring, as this is conductive to performance development.

The aim of the present study was to synthesize and characterize of divalent metal ions of Nickel, Copper and Zinc complexes of 5-chloro 2-furaldehyde thiosemicarbazone. Firstly ligand was prepared from the reaction between 5-Chloro-2-furaldehyde and thiosemicarbazide, the second step involved the synthesis of Ni(II), Cu(II) and Zn(II) complexes of 5-chloro 2-furaldehyde thiosemicarbazone. The prepared compounds (ligand or complex) was characterized using different analytical techniques such as elemental analysis, and IR, UV, Mass and 1H NMR tests, the results obtained showed that the ligand and its Ni(II), Cu(II), Zn(II) and Co(II) complexes of 5-chloro 2-furaldehyde thiosemicarbazone were prepared successfully.

In this article, we study the asymptotic dynamics of a stochastic strongly damped plate system with homogeneous Neumann boundary conditions and multiplicative noise. First, we investigate the existence and uniqueness of solutions in infinite-dimensional dynamical systems using the notion of mild solutions, and then we examine the presence of a bounded absorbing set. Finally, we investigate the asymptotic compactness by using the decomposition technique to prove the existence of a random attractor.

5-chloropyridine-2-carbaldehydethiosemicarbazone (HL1) and its nickel(II), cobalt(II), Zinc(II) and copper(II) complexes: [Ni(HL1)2], [Co(HL1)2], [Zn(HL1)2], [Cu(HL1)2], [Cu(HL1)], were synthesized and characterized. The ligand has been characterized by elemental analyses, IR, 1H NMR and Mass spectroscopy. The dentate nature of the ligand is evident from the spectral obtained data and literature.

The study was conducted to evaluate the physicochemical properties and fatty acids content of lard. The qualitative determination of fatty acids of using GC-MS analysis revealed that the higher concentrations of fatty acids 9- octadecenoic acid methyl ester Hexadecenoic acid, methyl stearate and 9,12-Octadecadienoic acid (Z,Z)- with different concentrations. Many physical and chemical properties of lard were determined in the study including the density, viscosity, refractive index. Peroxide value, acid value, iodine value and saponification value. Also, we determine rancidity of lard.

The present study was conducted to detect and diagnose Fasciola spp. in sheep in Salah al-Din governorate for period from September 2019 until March 2020. The study included examining 200 fecal samples from both sexes, and the adult age group, by using sedimentation method and microscopic examination. The results showed the total rate of infection with Fasciola spp.was 5.5% (11/200). Distribution of infection according to period of study showed that the highest rate of infection was in January and February (79.13%) (34.10%) respectively, and no infection rate was observed in September and March. The study showed the measurement of hepatic worms eggs isolated from infected sheep ranges between (142x80) µm, ellipsoidal in shape with operculum and this features are within the eggs of F. hepatica.

One of the most serious problems facing student housing at public universities is fire hazards. The fire risk is significantly increased by some works that may be performed in the facilities and laboratories. The primary concern with any fire is to save lives. In the worst case, they lose consciousness, making them vulnerable to mistakes. The building should be designed to help the occupants in this situation. The passive fire protection system in the building should be always accessible and work well because it is permanent and is usually used frequently until the occupants are familiar with it. Occupants should be able to use the Means of Escape (MoE) design elements in the building to escape the fire even if the active fire protection system is not working or the fire department arrives too late at the scene. Therefore, this research was conducted to determine the functionality of Means of Escape (MoE) in building design and their effectiveness in allowing all occupants of student housing in public universities to escape during evacuation. The functionality of Means of Escape (MoE) in building design and their effectiveness for student housing in public universities is of great importance because they can reduce fire accidents, property damage, and loss of life. The methods used were observation, review of legal requirements and other fire safety-related rules and regulations. In addition, the research was also based on pilot testing of the questionnaire. In the case of compliance and design consideration, performance is evaluated by examining whether the elements meet the requirements of the regulations, while in the case of occupant findings, performance is evaluated based on the difficulty and complexity of the complaints and their solutions. In conclusion, the authorities and public universities need to work together to implement an adequate fire safety system in student housing in public universities.

Background: Polycystic ovary syndrome (PCOS) is found in 6–15% of females of reproductive age (1, 2) with polycystic ovaries on pelvic ultrasonography. Polycystic ovaries are nonspecific on ultrasound, overlapping with findings in 40% of people who do not have the syndrome. Aim: To assess the advantages of transabdominal pelvic ultrasound in the confirmation of PCOS. Methods: This prospective investigation compared 45 female participants with PCOS, average age 14.9 years (group I) with 82 female participants with acute appendicitis, average age 14.3 years (group II), at Hashim Bin Al-hussein Military Hospital, Zarqa, Jordan, during the period 2018-2020. Transabdominal pelvic ultrasound was assessed in the two groups. Ovarian volume (0.5 x length x width x thickness) and follicle (3–10 mm in a single plane (follicle number per section) for each ovary) were followed up. The modified Rotterdam criteria (volume more than 10 ml +/- number of follicles more than 10) for polycystic ovaries were used. Pelvic transabdominal ultrasound was performed in cases of doubtful appendicitis with longitudinal and transverse images of the two ovaries and uterus (and endometrial stripe). Correlation between continuous variables was conducted using nonparametric Wilcoxon tests and correlation between categorical variables was performed using Fisher’s exact test. A P-value of less than 0.05 was considered statistically significant. Results: The modified Rotterdam criteria for polycystic ovary morphology (PCOM) were recorded more commonly in group I (66.7% [30/45]) than in group II (10.97% [9/82]). In group I, 30 participants were positive for PCOM: 12/30 (40%) by number of follicles more than 10, 4/30 (13.3%) by volume and 14/30 (46.7%) by number and volume. Most ultrasounds were accurate for confirmation (group I = 93.3% [42/45] and group II = 91.5% [75/82]). In group II, nine participants were positive for PCOM: three by follicle criteria, two by volume and four by volume and ..........

Background: Various international guidelines have been developed regarding Helicobacter pylori (H. pylori) management, as it is infecting more than half of the world's population. Sudan's health system lacks guidelines regarding H. pylori management, leading to a discrepancy in practice. Investigating the current approach could be a step forward in the formulation of a national consensus in the management of H. pylori. Methods: A cross-sectional study was conducted among medical doctors currently working in Khartoum, Sudan. Participants were enrolled from platforms of medical associations through an online questionnaire. The questionnaire was scored out of 25 points, and scoring 13 or above considered a good approach. Data analysis was carried out using Statistical Package for Social Sciences (SPSS). Results: A total of 358 medical doctors participated in the study. The mean (±SD) score was 12.9(±4.5). Those who were using textbooks, campaigns, symposiums or general medical information to their primary Source of knowledge significantly scored higher. The most selected indication for both diagnosis (76.8%) and treatment (67.6%) was an active peptic ulcer. Stool antigen test (SAT) was the most preferred test (70.7%). The majority of respondents selected triple therapy (82.1%) as a first-line regimen. Only 37.7% confirmed the eradication after four weeks of stopping the treatment. They ensure eradication mainly through SAT (29%). Conclusion: A suboptimal approach was noted among medical doctors of Khartoum, Sudan, regarding H. pylori management. Efforts should be invested in forming national guidelines and the implementation of continuous medical education programs. Keywords: Helicobacter pylori, Medical doctor, Sudan.

Worldwide biodiversity is impacted strikingly by global environmental change, and thus its impact is reflected in all life aspects. Identifying microorganisms in environmental samples, particularly soil could be a valuable interest to study their effect on soil quality and plant growth. Through this study, we conducted a molecular characterization of bacteria found in the rhizosphere of Medicago sativa plants grown in Hai'l soil and we highlighted their main properties. The analysis of sequences revealed that the main bacterial isolates were Pseudarthrobacter, Metabacillus, Priestia, and Massilia species. According to the sequence analyses and the phylogeny tree results, some of the identified bacteria were classified at the species level: one of the pseudarthrobacter isolates was identified clearly as Pseudarthrobacter phenanthrenivorans; Metabacillus isolates grouped with Metabacillus sediminilitoris and the two Priestia isolates closely related to Priestia aryabhattai. We concluded that Hai'l soil is a niche of diverse bacteria with a high interest in soil environment and ecosystems. Further studies are required for further classification of all identified bacteria and to define their specific role in the environment.

The present study focuses on the indiscriminate disposal of personal protective equipment (PPEs) and resulting environmental contamination during the 3rd wave of COVID-19-driven global pandemic in the Chittagong metropolitan area, Bangladesh. Because of the very high rate of infection by the delta variant of this virus, the use of PPEs by the public is increased significantly to protect the ingestion/inhalation of respiratory droplets in the air. However, it is a matter of solicitude that general people throw away the PPEs to the dwelling environment unconsciously. With the increase of inappropriate disposal of PPEs (i.e., mostly the disposable face masks made from plastic microfibers), the possibility of transmission of the virus to the general public cannot be neglected completely. This is because this virus can survive for several days on the inanimate matter like plastics and fibers. At the same time, the result of environmental contamination by microplastic/microfiber has been widespread which eventually creates the worst impact on ecosystems and organisms. The present results may help to increase public perception of the use and subsequent disposal of PPEs, especially the face masks.

In this study the effects due to temperature and shear rate on viscosity for Co3O4/glycol based Nano fluids at different concentration of metal oxide and different temperatures were experimentally investigated. The structure of the prepared Co3O4/glycol nanoparticles was confirmed using XRD (X-Ray Diffraction) technique. All viscosity measurements were conducted using a capillary viscometer, the viscosity experiment were carried out at wide temperatures ranging between 20°C and 80°C to determine their applicability in such range. The viscosity data were collected using a programmable rhemoter. The result showed that the Co3O4 glycol exhibit increasing viscosity with increasing nanoparticle loading and decreasing viscosity with increasing temperature.

PURPOSE Patient portal secure messages are not always authored by the patient account holder. Understanding who authored the message is particularly important in an oncology setting where symptom reporting is crucial to patient treatment. Natural language processing has the potential to detect messages not authored by the patient automatically. METHODS Patient portal secure messages from the Memorial Sloan Kettering Cancer Center were retrieved and manually annotated as a predicted unregistered proxy (ie, not written by the patient) or a presumed patient. After randomly splitting the annotated messages into training and test sets in a 70:30 ratio, a bag-of-words approach was used to extract features and then a Least Absolute Shrinkage and Selection Operator (LASSO) model was trained and used for classification. RESULTS Portal secure messages (n = 2,000) were randomly selected from unique patient accounts and manually annotated. We excluded 335 messages from the data set as the annotators could not determine if they were written by a patient or proxy. Using the remaining 1,665 messages, a LASSO model was developed that achieved an area under the curve of 0.932 and an area under the precision recall curve of 0.748. The sensitivity and specificity related to classifying true-positive cases (predicted unregistered proxy-authored messages) and true negatives (presumed patient-authored messages) were 0.681 and 0.960, respectively. CONCLUSION Our work demonstrates the feasibility of using unstructured, heterogenous patient portal secure messages to determine portal secure message authorship. Identifying patient authorship in real time can improve patient portal account security and can be used to improve the quality of the information extracted from the patient portal, such as patient-reported outcomes.

Background: Many clinical trials leverage real-world data. Typically, these data are manually abstracted from electronic health records (EHRs) and entered into electronic case report forms (CRFs), a time and labor-intensive process that is also error-prone and may miss information. Automated transfer of data from EHRs to eCRFs has the potential to reduce data abstraction and entry burden as well as improve data quality and safety. Methods: We conducted a test of automated EHR-to-CRF data transfer for 40 participants in a clinical trial of hospitalized COVID-19 patients. We determined which coordinator-entered data could be automated from the EHR (coverage), and the frequency with which the values from the automated EHR feed and values entered by study personnel for the actual study matched exactly (concordance). Results: The automated EHR feed populated 10,081/11,952 (84%) coordinator-completed values. For fields where both the automation and study personnel provided data, the values matched exactly 89% of the time. Highest concordance was for daily lab results (94%), which also required the most personnel resources (30 minutes per participant). In a detailed analysis of 196 instances where personnel and automation entered values differed, both a study coordinator and a data analyst agreed that 152 (78%) instances were a result of data entry error. Conclusions: An automated EHR feed has the potential to significantly decrease study personnel effort while improving the accuracy of CRF data.

Establishment of diagnostic reference levels (DRLs) is an essential radiation optimization tool used to indicate optimum practice and radiation protection. This study aimed to report the current computed tomography (CT) of the chest–abdomen–pelvis radiation practice in Sudan as a part of the DRL establishment effort and dose optimization. CT radiation doses were collected from 530 patients of age ranging between 28 and 85 y and body weight ranging between 65 and 120 kg. DRLs were calculated based on the 75th percentile of dose length product (DLP) and CT dose index volume (CTDIvol). Effective and organ doses were calculated using the National Cancer Institute dosimetry system for the CT programme. The proposed DRLs are CTDIvol, 6 mGy, and DLP, 970 mGy.cm, and an effective dose of 9.9 mSv. Organ dose estimation showed that the thyroid received the highest dose during the scan.

The objective of this study is to estimate the annual effective dose for cardiologists and nurses by measuring Hp(10) and Hp(0.07) during cardiac catheterization procedures. A total of 16 staffs members were working in interventional cardiology during 1 year at a tertiary hospital. The occupational dose was measured using calibrated thermo-luminescent dosemeters (TLD-100, LiF:Mg,Ti). The overall mean and range of the annual Hp(10) and Hp(0.07) (mSv) for cardiologists were 3.7 (0.13–14.5) and 3.2 (0.21–14.7), respectively. Cardiologists were frequently exposed to higher doses compared with nurses and technologists. The exposure showed wide variations, which depend on occupation and workload. Staff is adhered to radiation protection guidelines regarding shielding the trunk, thyroid shield, thus appropriately protected. Lens dose measurement is recommended to ensure that dose limit is not exceeded.

Background and aims: Although blood transfusion is generally believed to save human lives, blood can be a vehicle for the transmission of some infectious and parasitic diseases including malaria. So, this study aims to determine the prevalence of blood transfusion malaria among blood donors in the Central Blood Bank in Kassala State, according to age and blood groups. Materials and methods: A cross-sectional study was carried out in the central blood bank in Kassala State among blood donors; this study involved one hundred blood samples, collected from donors aged from 18 to 41 years. Results: The results showed that 1 (1%) of the donors was infected with the malaria parasite. The results also showed that the species of the malaria parasite was Plasmodium falciparum; the other Plasmodium species were not found. The results revealed that most donors were blood group O, while AB was the least common blood group; the blood group that harbored the malaria parasite was blood group O, and the other blood groups tested negative. The results also showed the highest number of blood donors was found in the age group of 24-29, and the positive donor was found in the same age group. Conclusions: Both the blood films and immune chromatography test showed one positive result for the donor and the percentage of blood transfusion malaria was 1%.

A field experiment was carried out in Nineveh Governorate during the winter season of 2018-2019 to study the effect of spraying with seaweed extracts Algaren and ALG6000 on some vegetative, root, qualitative and mineral growth characteristics of leaves and dry seeds of two cultivars of broad Beans. The study included eighteen treatments in each replicate, consisting of a control treatment (without any addition) and spraying with four levels of seaweed extract Algaren (2, 4, 6 and 8 cm3.l-1) as well as Four-level spraying of ALG6000 seaweed extract (2, 4, 6 and 8 cm3.l-1) on two broad bean cultivars. Algaren achieved the best value over ALG6000 in the studied traits. The French cultivar Aquadulce recorded better results than the Spanish cultivar Luzde Otono, with a dry root weight, leaf area, and nitrogen and phosphorous content of protein and carbohydrates in the dry seeds. In contrast, the Spanish bean variety Luzde Otono recorded the highest significant value in a number of root nodes, the content of leaves and dry seeds of potassium.

Introduction: Bladder cancer (BC) is one of the most frequent malignancy of the urinary tract. Recent studies demonstrated the role of aquaporins urothelial tumor cells (AQPs) as potential prognostic factor for tumor progression and invasion. In this study we investigated the AQP3 expression levels inside primary superficial (pTa) low grade bladder cancer, correlating with pathological parameters and clinical outcomes. Materials and methods: We retrospectively analyzed tumor samples of 66 patients with diagnosis of superficial urothelial (pTa) bladder cancer between 1997 and 2007. All patients underwent transurethral bladder resection (TURB ) and immediate single instillation of mitomycin C. All tumors samples were blindly reviewed by two expert anatomopathologists and only pTa low grade urothelial bladder cancer were included. Cancer recurrence was defined as the detection of bladder lesions during follow-up cystoscopy. AQP3-immunoreactive areas detected at immunohistochemical analysis were classified as AQP3 positive. Results: Of these 60.6% of patients was detected as negative for AQP3 expression. Forty-two patients develop cancer recurrence during follow-up with a mean progression free survival of 16.44 months. The absence of reaction for AQP3 was observed 56% (9/16) tumor grading G1 and 62% (31/50) tumor grading G2. No correlation was observed with sexual gender, grading of tumor differentiation, and recurrence of cancer disease. Kaplan-Meier curves of disease-free survival (DFS) showed a significant separation ( p = 0.028) between patients AQP3-positive and AQP3-negative. It was observed a mean DFS of 23.83 and 14.43 months respectively in absence and presence of AQP3 expression. Conclusion: AQP3 expression is related to disease-free interval (DFI) and the absence of AQP3 expression correlates with a late relapse. The expression of AQP3 does not provide a reproducible quantitative aspect. AQP3 are not suitable to forecast tumor cell behavior but they perform a role as regulator for tumor cell homeostasis and for additional therapeutic developments.

Diabetic peripheral neuropathy (DPN) is a common diabetes complication (DM). Aldose reductase -2 (ALR-2) is an oxidoreductase enzyme that is most extensively studied therapeutic target for diabetes-related complications that can be inhibited by epalrestat, which has severe adverse effects; hence the discovery of potent natural inhibitors is desired. In response, a pharmacophore model based on the properties of eplarestat was generated. The specified pharmacophore model searched the NuBBEDB database of natural compounds for prospective lead candidates. To assess the drug-likeness and ADMET profile of the compounds, a series of in silico filtering procedures were applied. The compounds were then put through molecular docking and interaction analysis. In comparison to the reference drug, four compounds showed increased binding affinity and demonstrated critical residue interactions with greater stability and specificity. As a result, we have identified four potent inhibitors: ZINC000002895847, ZINC000002566593, ZINC000012447255, and ZINC000065074786, that could be used as pharmacological niches to develop novel ALR-2 inhibitors.

Protein tyrosine phosphatase-1B (PTP-1B) is a well-known therapeutic target for diabetes and obesity as it suppresses insulin and leptin signaling. PTP-1B deletion or pharmacological suppression boosted glucose homeostasis and insulin signaling without altering hepatic fat storage. Inhibitors of PTP-1B may be useful in the treatment of type 2 diabetes, and shikonin, a naturally occurring naphthoquinone dye pigment, is reported to inhibit PTP-1B and possess antidiabetic properties. Since the cell contains a large number of phosphatases, PTP-1B inhibitors must be effective and selective. To explore more about the mechanism underlying the inhibitor's efficacy and selectivity, we investigated its top four pharmacophores and used site-directed mutagenesis to insert amino acid mutations into PTP-1B as an extension of our previous study where we identified 4 pharmacophores of shikonin. The study aimed to examine the site-directed mutations like R24Y, S215E, and S216C influence the binding of shikonin pharmacophores, which act as selective inhibitors of PTP-1B. To achieve this purpose, docking and molecular dynamics simulations of wild-type (WT) and mutant PTP-1B with antidiabetic compounds were undertaken. The simulation results revealed that site-directed mutations can change the hydrogen bond and hydrophobic interactions between shikonin pharmacophores and many residues in PTP-1B's active site, influencing the drug's binding affinity. These findings could aid researchers in better understanding PTP-1B inhibitors' selective binding mechanism and pave the path for the creation of effective PTP-1B inhibitors.

Yellow nail syndrome is a rare lymphatic abnormality without a clear pathogenesis. Hereby, we report A 70-year Sudanese female who presented with recurrent cough, recurrent lower limb swelling and yellowish nail discoloration diagnosed as yellow nail syndrome but unfortunately passed away due to acute respiratory distress syndrome (ARDS).

Size-specific dose estimate (SSDE), which can be calculated by measuring the effective diameter (De) or water equivalent diameter (Dw) of the patient, is one of the recent approaches for verifying the individual doses during computer tomography (CT) examinations. This work aimed to compare the Dw estimated by the AutoWED tool and IndoseCT software and to investigate CT axial (ARH) and paediatric head (PH) protocols used in southern Saudi Arabia to calculate the dose received by paediatric patients using metrics of volume CT dose index (CTDIvol) and SSDE. The distribution between the ARH and PH protocols was 57.8 and 42.2%, respectively. There was no significant difference in Dw values between the AutoWED tool and the IndoseCT program (0.13%). Including CT table or other objects during estimation of Dw can lead to variation up to 11.4%. The impact of selecting IndoseCT options to identify the border of the patient may be part of the explanation for these variations. A strong linear relationship was obtained between De and Dw in paediatric head size (R2 = 0.96). Using IndoseCT, for 0–1.5, 1.5–5 and 5.0–18 age groups (years), the Dw was found to be 13.2, 15.3 and 16.8 cm, respectively. The SSDE for the PH protocol was substantially lower than that of the ARH protocol. As a result, education of the individuals engaging in paediatric CT examinations is necessary for dose optimization.

IntroductionNames are a reflection of identity and often have personal meaning. The chronic mispronunciation of names can undermine one's identity and be experienced as a microaggression. This workshop aims to provide historical context for names as well as resources for correct name pronunciation.MethodsWe developed a 60-minute interactive virtual workshop with didactics, small-group sharing of personal experiences, and case discussions. We used an anonymous postworkshop survey to evaluate workshop effectiveness.ResultsWe presented the workshop at one local academic conference and two local educational conferences to learners of all levels from medical students to faculty. We collected postworkshop survey results from 78 participants of diverse racial and ethnic backgrounds. Participants reported learning historical context, ways to ask about correct name pronunciation, correcting name mispronunciation, documenting pronunciation, and sources for applications to practice. The main barriers to implementing workshop lessons included personal and structural factors.DiscussionThis workshop effectively fills an educational gap by addressing the importance of correct name pronunciation in order to provide a more inclusive environment for clinicians and patients alike.

The current experiment previous from beginning of September 2019 until March 2020 and a It checkup 165 liver tissue of adult sheep from both sexes slaughtered in slaughterhouses and butchers' stores in Salahuddin Governorat. Since the liver is one of the important organs where most of the body's metabolism activities occur in it, as it performs the metabolism of protein, metabolism of fats and the formation of bile, and the liver works to reduce toxic substances entering the body and plays a role in the immune response of the body so diseases that Liver disease affects animals directly [1]. The results are shown through macroscopic and histological examinations in the examined livers, presence of both acute and chronic phases. Where the chronic phase was the dominant, and showed infiltration of the inflammatory cells represented by lymphocytes, macrophages, plasma and eosinophils, as well as many necrotic foci, characterized by proliferation of fibrous tissue and thickening and expansion of the bile ducts compared to liver. The natural non-infection liver without fasciola hepatica whose cells are in form of polygonal rows in a radial order and each hepatic cell has a dark colored

The problem tackled in this paper is the estimation of variogram function Indicator of spatial stochastic process for the Levels of groundwater, by the method of weighted Least squares. This methods is well known in regression analysis in estimating the coefficient of ression model. After defining the indicator variable the parameters of Indicator variogram estimated based on mean squares error. The final formula of weighted least squares estimator can be not be solved exactly, then through the use of iterative Newten - Raphson algorithm and for some iterations the convergence of solution is obtained with certain termination criterion or number of repeats (that used in this paper).

Background Pudendal neuropathy is a chronic, disabling form of perineal pain that involves the pudendal nerve, a mixed somatic and autonomic nerve that originates from sacral nerve roots. Peripheral nerve stimulation of the pudendal nerve can be useful to decrease symptom burden in patients who have failed initial conservative treatment modalities. Methods In this manuscript, we describe an approach to the placement of a peripheral nerve stimulator for the treatment of pudendal neuralgia. We present a case of complex pelvic neuropathy and review the factors that lead to successful placement. Technical aspects of stimulator placement and ultrasound landmarks are reviewed. Results A lateral to medial approach with ultrasound guidance at the level of the ischial spine is likely to facilitate proper lead placement along the course of the pudendal nerve. Aftercare and adherence to postimplant activity restrictions–particularly avoiding use of the extremes of hip flexion and extension for four weeks—lead to the absence of lead migration. Conclusions Pudendal nerve stimulation is an emerging technique for neuromodulation of refractory pudendal neuralgia. Ultrasound-guided pudendal nerve stimulation is a viable technique for neuromodulation of pudendal neuralgia. Optimization of patient selection, ultrasound guidance, and proper adherence to postimplant activity restrictions may be helpful for long-term therapeutic success.

BackgroundChronic headaches are the second most prevalent disease and second most common cause for years lived with disability worldwide. Occipital neuralgia can cause headaches or be present in addition to other more prevalent causes of headache. If these headaches fail to respond to conservative and pharmacological therapy, physicians proceed to more invasive treatments, starting with infiltration of the greater occipital nerve with local anesthetic with or without corticosteroids, followed by nerve ablation or stimulation. Occipital nerve stimulation gained more popularity as the technology improved and more pain physicians received training on interventional procedures.MethodsIn this manuscript, we are presenting our experience with ultrasound-guided implant of occipital nerve stimulators using peripheral nerve stimulator systems. After confirming appropriateness of treatment by a successful occipital nerve block (i.e., resulting in >50% relief in patients’ pain intensity), we implanted five stimulator systems in three patients (two bilateral).ResultsWe followed these patients for an average of eight months, and the average pain reduction was ∼50%. We did not observe any adverse events during or immediately after surgery. One patient developed an adverse reaction to the adhesive of the battery transmitter, but it was not severe enough to stop her from using the stimulator.ConclusionsConsidering the ease of implant and minimal side effects, implant of peripheral nerve stimulators to stimulate the occipital nerve is a promising treatment modality for patients with chronic headache who present with features of occipital neuralgia. However, wider use of this treatment modality is subject to further studies.

The present study has been carried out to investigate the mechanisms of sol–gel reactions using TEOS as precursor in the presence of acid or base catalyst. The gels were prepared by hydrolysis of TEOS using hydrochloride acid or ammonium hydroxide catalyst. The obtained gels were also characterized by FTIR spectroscopy. The results of FTIR spectroscopy indicated the existence of silanol and siloxane bonds; due to the formation of hydrolyzed species as reactive intermediate compounds in initial stage converted by condensation reactions to gels as ultimate products. Accordingly, appropriate mechanisms have been proposed for sol – gel reaction using TEOS as precursor in the presence of acid or base catalyst. These mechanisms involve three-steps SN2 mechanisms for base catalyzed hydrolysis reaction of TEOS and SN1 mechanisms for acid catalyzed hydrolysis reaction of TEOS. Three mechanisms have been also proposed for condensation reaction as second stage in sol-gel process. These mechanisms include alcoxolation, oxolation and oltaion.

Background There is an exponential growth of public concern worldwide regarding the exposure to electromagnetic fields (EMF) generated by wind turbines. The high concern of the general population enhances the fact that EMF exposure remains a crucial issue that demands specific actions and reliable data to evaluate possible health hazards. Materials and Methods EMF exposure measurements were conducted in two wind farm (W/F) areas in Greece. The magnetic field strength concentrated in the proximity of 22 wind turbines (20 type of Gamesa Eolica Siemens of total power of 17 MW and 2 type of E53 Enercon, 800 KW each). Measurements were conducted using a Narda-NBM-550 basic unit (Narda Safety Test Solutions Company) using EHP-50F probe. The EMF exposure measurements were processed applying the weighted peak method (WPM), according to the 2013/35/EU Directive. WPM provides correction of the measured value of pulse signals, taking into account the phases of the various frequency components. The data were classified under two scenarios of EMF exposure: ‘high wind’ and ‘low wind’ conditions. Results The variation of the magnetic field strength was calculated between 1.13 and 1.42% (WPM). Measurements indicate that the intensity of the emitted magnetic field at the base of the wind turbines, in both high and low wind conditions, was relatively low (mean = 0.146 μT), while decreasing rapidly with increasing distance and reaching background values 6 m from the base. Conclusion The results of the present study indicate that EMF levels are similar or even lower compared to those in urban areas and well below the national and international safety limits.

In this study, we investigated the potential role of the karrikin receptor KARRIKIN INSENSITIVE2 (KAI2) in the response of Arabidopsis seedlings to high-temperature stress. We performed phenotypic, physiological and transcriptome analyses of Arabidopsis kai2 mutants and wild-type (WT) plants under control (kai2_C and WT_C, respectively) and 6- and 24-h heat stress conditions (kai2_H6, kai2_H24, WT_H6 and WT_H24, respectively) to understand the basis for KAI2-regulated heat stress tolerance. We discovered that the kai2 mutants exhibited hypersensitivity to high-temperature stress relative to WT plants, which might be associated with a more highly increased leaf surface temperature and cell membrane damage in kai2 mutant plants. Next, we performed comparative transcriptome analysis of kai2_C, kai2_H6, kai2_H24, WT_C, WT_H6 and WT_H24 to identify transcriptome differences between WT and kai2 mutants in response to heat stress. K-mean clustering of normalized gene expression separated the investigated genotypes into three clusters based on heat-treated and non-treated control conditions. Within each cluster, the kai2 mutants were separated from WT plants, implying that kai2 mutants exhibited distinct transcriptome profiles relative to WT plants. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses showed a repression in ‘misfolded protein binding’, ‘heat shock protein binding’, ‘unfolded protein binding’ and ‘protein processing in endoplasmic reticulum’ pathways, which was consistent with the downregulation of several genes encoding heat shock proteins and heat shock transcription factors in the kai2 mutant versus WT plants under control and heat stress conditions. Our findings suggest that chemical or genetic manipulation of KAI2 signaling may provide a novel way to improve heat tolerance in plants.

This cross-sectional study assesses changes in the volume of patient-initiated messages to clinicians associated with release of test results before and after implementation of the 21st Century Cures Act.

This study investigates the Covid-19 driven indiscriminate disposal of PPE wastes (mostly face mask and medical wastes) in Chittagong metropolitan area (CMA), Bangladesh. Based on the field monitoring, the mean PPE density (PPE/m