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OBJECTIVE To evaluate breast cancer patients with low F18-fluorodeoxy-glucose positron emission tomography/computed tomography scan (FPET) of axilla standardised maximum uptake value (SUVmax) along with their histopathological findings regarding axillary lymph node metastasis (LNM). STUDY DESIGN A descriptive study. Place and Duration of the Study: Adana City Education and Research Hospital, Turkey, from January 2015 to October 2018. METHODOLOGY The current study analysed the findings of 113 patients according to age, histopathological axillary LNM, estrogen and progesterone receptor status, tumour size, histological grade, Ki-67, HER2 and preoperative FPET SUVmax findings. Histopathological and immunohistochemical comparisons were made between FPET axilla SUVmax and univariate and multivariate parameters in breast carcinoma in terms of LNM. RESULTS The authors analysed the receiver operator characteristic curve for the FPET axilla SUVmax and set the cut-off value to 1.84 to predict LNM. However, it was also found that the SUVmax detected metastases in the axilla at values lower than 1.84. In the multivariate analysis, a statistically significant relationship was found between axilla LNM cases that have FPET axilla SUVmax less than 1.84, a Ki-67 index greater than 15% and tumour size greater than 2 cm (p

Background and Aims The complete pathological response (pCR) following neoadjuvant chemotherapy (NAC) in breast cancer is essential for the accurate prediction of prognosis. We aimed to evaluate the efficacy of the presence and type of peritumoral edema detected by magnetic resonance imaging (MRI) in predicting pCR to NAC in breast cancer patients. Methods and Results One hundred five patients with the diagnosis of invasive carcinoma were evaluated by MRI before NAC. Edema was evaluated in fat-suppressed T2-weighted images. The patients were categorized into three groups: patients with no peritumoral edema, patients with peritumoral edema, and patients demonstrating subcutaneous edema. The cases were categorized as being pCR and non-pCR. Molecular subtypes, lymphovascular invasion (LVI), tumor size, and apparent diffusion coefficient (ADC) were evaluated. A positive relationship was found between the presence of edema and tumor size. Subcutaneous edema was found to be statistically higher in non-pCR patients. While the number of pCR patients with subcutaneous edema was 17 (30.4%), the number of non-pCR patients with subcutaneous edema was 26 (53.1%) ( p = 0.018). LVI was found to be statistically higher in patients with edema. The number of edema-negative and LVI (+) patients was 4 (15.4%), while the number of edema-positive and LVI (+) patients was 28 (35.4%) ( p = 0.042). Intratumoral and peritumoral ADC values were significantly higher in tumors with edema. Conclusion The presence of subcutaneous edema and LVI may be utilized for the prediction of pCR outcomes in breast cancer patients scheduled for NAC treatment.

Aim: Studies on childhood soft tissue tumors have generally been conducted with malignant tumors. There are few studies in the literature comprising all soft tissue tumors. The current study aimed to examine the incidence of all benign and malignant soft tissue tumors during childhood in East Mediterranean region.Materials and Methods: This study retrospectively analyzed the data gathered from patients diagnosed with soft tissue tumors according to the WHO 2020 classification. It focused on those aged 0–18 years that underwent excisional biopsy at Adana City Training and Research Hospital (Adana, Turkey) between 2014 and 2020.Results: Of the total patients, 47.5% were female and 52.5% male. Of these, 87.2% of the cases were benign, 9.2% malignant, and 3.6% intermediate. Hemangioma (55%) was the most common benign soft tissue tumor, and the most common location was the head–neck. Other benign soft tissue tumors were neurofibroma (8.8%), lipoma (6.1%), schwannoma (5.1%), and neuroma (4.4%). Rhabdomyosarcoma (53.2%) was the most common malignant soft tissue tumor. The embryonal subtype was the most common (36.6%). Other malignant soft tissue tumors were extra-osseous PNET/Ewing’s sarcoma (16.6%), synovial sarcoma (13.3%), and leiomyosarcoma (3.3%).Conclusion: Similar to the literature, in this study, the most common benign soft tissue tumor in children was hemangioma, and the most common malignant soft tissue tumor was rhabdomyosarcoma. It is hoped that this study will contribute to the literature as it is the first study to cover all childhood soft tissue tumors at national and regional scale.