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516 results on '"Jonathan L. Haines"'

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1. The genetic architecture of Alzheimer disease risk in the Ohio and Indiana Amish

2. Statistical driver genes as a means to uncover missing heritability for age-related macular degeneration

3. eMERGEing progress in genomics---the first seven years

4. New insights into the genetic etiology of Alzheimer's disease and related dementias

5. Systems genomics in age-related macular degeneration

6. Genetic architecture of RNA editing regulation in Alzheimer's disease across diverse ancestral populations

7. An association test of the spatial distribution of rare missense variants within protein structures identifies Alzheimer's disease-related patterns

8. Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease

9. A locus at 19q13.31 significantly reduces the ApoE ε4 risk for Alzheimer’s Disease in African Ancestry

10. Corrigendum: An association test of the spatial distribution of rare missense variants within protein structures identifies Alzheimer's disease–related patterns

11. Linkage of Alzheimer Disease Families with Puerto Rican Ancestry Identifies a Chromosome 9 Locus

12. Large‐scale sequencing studies expand the known genetic architecture of Alzheimer's disease

13. Using linkage analysis to identify novel gene‐gene interactions in Alzheimer’s disease

14. Genome‐wide meta‐analysis of late‐onset Alzheimer’s disease using rare variant imputation in 65,602 subjects identifies risk loci with roles in memory, neurodevelopment, and cardiometabolic traits: The international genomics of Alzheimer’s project (IGAP)

15. Assessing whole genome sequencing variation for Alzheimer’s disease in 4707 individuals from the Alzheimer’s Disease Sequencing Project (ADSP)

16. Transcriptomic characterization of a Puerto Rican Alzheimer disease cohort implicates convergent immune‐related pathways

17. Search for protective genetic variants in Alzheimer disease in the U.S. Midwestern Amish

18. Structural characterization of rare missense variants within known neurodegenerative disease proteins

19. A multiancestry analysis of Alzheimer’s disease coexpressed gene networks identifies a common immune signaling pathway regulated by granulocyte‐colony stimulating factor (G‐CSF)

20. Genome‐wide interaction study of smoking in Alzheimer’s disease

21. Increased APOE‐e4 expression is associated with reactive A1 astrocytes and may confer the difference in Alzheimer disease risk from different ancestral backgrounds

22. Comparative trans‐ethnic meta‐analysis of whole exome sequencing variation for Alzheimer’s disease (AD) in 18,402 individuals of the Alzheimer’s Disease Sequencing Project (ADSP)

23. iPSC‐derived neurons and microglia with an African‐specific ABCA7 frameshift deletion have impaired function

24. IncreasedAPOEε4expression is associated with reactive A1 astrocytes and the difference in Alzheimer Disease risk from diverse ancestral backgrounds

25. Genetic Variants and Functional Pathways Associated with Resilience to Alzheimer’s Disease

26. Genetic variants and functional pathways associated with resilience to Alzheimer's disease

27. Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression

28. Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

29. Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma

30. Identification of rare noncoding sequence variants in gamma-aminobutyric acid A receptor, alpha 4 subunit in autism spectrum disorder

31. Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci

32. A population-specific reference panel empowers genetic studies of Anabaptist populations

33. Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers

34. New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics

35. Genetic correlations between intraocular pressure, blood pressure and primary open-angle glaucoma: a multi-cohort analysis

36. Joint Analysis of Nuclear and Mitochondrial Variants in Age-Related Macular Degeneration Identifies Novel Loci TRPM1 and ABHD2/RLBP1

37. Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study

38. CpG‐related SNPs in the MS4A region have a dose‐dependent effect on risk of late–onset Alzheimer disease

39. A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis

40. Rare variants and loci for age-related macular degeneration in the Ohio and Indiana Amish

41. RNA editing alterations in a multi-ethnic Alzheimer disease cohort converge on immune and endocytic molecular pathways

42. Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel

43. GWAS analysis implicates NF-κB-mediated induction of inflammatory T cells in multiple sclerosis

44. Genetic variation among 82 pharmacogenes: The PGRNseq data from the eMERGE network

45. Assessing the Association of Mitochondrial Genetic Variation With Primary Open-Angle Glaucoma Using Gene-Set Analyses

46. Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease

47. Association of APOE With Primary Open-Angle Glaucoma Suggests a Protective Effect for APOE ε4

48. Use of local genetic ancestry to assessTOMM40-523′ and risk for Alzheimer disease

49. Pedigree Selection and Information Content

50. P2‐108: WHOLE‐GENOME SEQUENCING IN NON‐HISPANIC WHITE FAMILIES IMPLICATES RARE VARIATION IN LATE‐ONSET ALZHEIMER'S DISEASE RISK

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