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Your search keyword '"Kriventseva, E."' showing total 2 results
Start Over Author "Kriventseva, E." Topic genetics
2 results on '"Kriventseva, E."'

1. The ecoresponsive genome of Daphnia pulex

Author

Colbourne, J. K., Pfrender, M. E., Gilbert, D., Thomas, W. K., Tucker, A., Oakley, T. H., Tokishita, S., Aerts, A., Arnold, G. J., Basu, M. K., Bauer, D. J., C當eres, C. E., Carmel, L., Casola, C., Choi, J. H., Detter, J. C., Dong, Q., Dusheyko, S., Eads, B. D., Frlich, T., Geiler-Samerotte, K. A., Gerlach, D., Hatcher, P., Jogdeo, S., Krijgsveld, J., Kriventseva, E. V., K�ltz, D., Laforsch, C., Lindquist, E., Lopez, J., Manak, J. R., Muller, J., Pangilinan, J., Patwardhan, R. P., Pitluck, S., Pritham, E. J., Rechtsteiner, A., Rho, M., Rogozin, I. B., Sakarya, O., Salamov, A., Schaack, S., Shapiro, H., Shiga, Y., Skalitzky, C., Smith, Z., Souvorov, A., Sung, W., Tang, Z., Tsuchiya, D., Tu, H., Vos, H., Wang, M., Wolf, Y. I., Yamagata, H., Yamada, Takuji, Ye, Y., Shaw, J. R., Andrews, J., Crease, T. J., Tang, H., Lucas, S. M., Robertson, H. M., Bork, P., Koonin, E. V., Zdobnov, E. M., Grigoriev, I. V., Lynch, M., Boore, J. L., Gerlach, Daniel, Kriventseva, Evgenia, and Zdobnov, Evgeny

Subjects
0106 biological sciences, Molecular Sequence Data, Gene Conversion, Gene Expression, Biology, Environment, 010603 evolutionary biology, 01 natural sciences, Genome, Daphnia pulex, Evolution, Molecular, 03 medical and health sciences, Genes, Duplicate, Gene Duplication, Gene duplication, Gene family, Animals, ddc:576.5, Gene conversion, Amino Acid Sequence, Gene, Ecosystem, Phylogeny, 030304 developmental biology, Regulation of gene expression, Genetics, 0303 health sciences, Multidisciplinary, Base Sequence, Daphnia/genetics/physiology, Metabolic Networks and Pathways/genetics, Gene Expression Profiling, fungi, Chromosome Mapping, Molecular Sequence Annotation, Sequence Analysis, DNA, biology.organism_classification, Adaptation, Physiological, Gene expression profiling, Daphnia, Gene Expression Regulation, Genes, Multigene Family, Metabolic Networks and Pathways
Abstract

We describe the draft genome of the microcrustacean Daphnia pulex, which is only 200 megabases and contains at least 30,907 genes. The high gene count is a consequence of an elevated rate of gene duplication resulting in tandem gene clusters. More than a third of Daphnia's genes have no detectable homologs in any other available proteome, and the most amplified gene families are specific to the Daphnia lineage. The coexpansion of gene families interacting within metabolic pathways suggests that the maintenance of duplicated genes is not random, and the analysis of gene expression under different environmental conditions reveals that numerous paralogs acquire divergent expression patterns soon after duplication. Daphnia-specific genes, including many additional loci within sequenced regions that are otherwise devoid of annotations, are the most responsive genes to ecological challenges.

Published
2011
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2. Genomic analysis of Drosophila chromosome underreplication reveals a link between replication control and transcriptional territories

Author

Belyakin, S., Christophides, G., Alekseyenko, A., Kriventseva, E., Belyaeva, E., Nanayev, R., Makunin, I., Hild, M., Beckmann, B., Haas, S., Koch, B., Solovyev, V., Busold, C., Fellenberg, K., Boutros, M., Vingron, M., Sauer, F., Hoheisel, J., Paro, R., and Heidelberg Fly Array Consortium

Subjects
DNA Replication, Male, Transcription, Genetic, Gene Dosage, Mitosis, Biology, Gene dosage, Genome, Chromosomes, Cell Line, Animals, Drosophila Proteins, Gene, Oligonucleotide Array Sequence Analysis, Regulation of gene expression, Genetics, Multidisciplinary, Polytene chromosome, Intercalary heterochromatin, Chromosome, Genomics, Biological Sciences, DNA-Binding Proteins, Gene Expression Regulation, Multigene Family, Mutation, Heterochromatin protein 1, Drosophila, Female
Abstract

In Drosophila polytene chromosomes, most late-replicating regions remain underreplicated. A loss-of-function mutant of the suppressor of underreplication [ Su(UR) ] gene suppresses underreplication (UR), whereas extra copies of this gene enhance the level and number of regions showing UR. By combining DNA microarray analysis with manipulation of the number of Su(UR) gene copies, we achieved genomic-scale molecular identification of 1,036 genes that are arranged in clusters located in 52 UR chromosomal regions. These regions overlap extensively (96%) but are not completely identical with late-replicating regions of mitotically dividing Kc cells in culture. Reanalysis of published gene expression profiles revealed that genomic regions defined by replication properties include clusters of coordinately expressed genes. Genomic regions that are UR in polytene chromosomes and late replicated in Kc cell chromosomes show a particularly common association with transcriptional territories that are expressed in testis/males but not ovary/females or embryos. An attractive hypothesis for future testing is that factors involved in replication control, such as SU(UR), may interact physically with those involved in epigenetic silencing of transcription territories.

Published
2005

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