1. Penetrating deep sclerectomy in primary open-angle and pseudoexfoliative glaucoma.
- Author
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Kozobolis V, Kalogianni E, and Sideroudi H
- Subjects
- Aged, Aged, 80 and over, Exfoliation Syndrome physiopathology, Female, Glaucoma, Open-Angle physiopathology, Humans, Intraocular Pressure physiology, Male, Middle Aged, Mitomycin therapeutic use, Postoperative Complications surgery, Prospective Studies, Tonometry, Ocular, Treatment Outcome, Exfoliation Syndrome surgery, Glaucoma, Open-Angle surgery, Sclera surgery, Sclerostomy methods
- Abstract
Purpose: To evaluate the outcomes of a new antiglaucoma surgical method, a modification of the standard deep sclerectomy, the penetrating deep sclerectomy., Participants: Patients with medically uncontrolled primary open-angle glaucoma or pseudoexfoliative glaucoma were prospectively, in a consecutive way, enrolled in this study., Methods: The study was conducted in Glaucoma Unit, Department of Ophthalmology, University of Hospital of Alexandroupolis, Greece, in 29 eyes of 29 patients. In a fornix-based surgical procedure, all eyes underwent the proposed penetrating deep sclerectomy (deep sclerectomy plus trabeculectomy) with the use of mitomycin C applied intraoperatively (0.2 mg/mL for 2 min). The follow-up period was 3 years. Ocular examination was conducted before the operation and at 1, 3, 6, 12, 18, 24, and 36 months postoperatively., Results: The average reduction in intraocular pressure at the end of follow-up was 11.24 (57.88%). The complete success rate (intraocular pressure ⩽21 mm Hg without medication) after 3 years was 58.6%. The qualified success rate (intraocular pressure ⩽21 mm Hg without or with medication) was 75.86%. Postoperatively, the mean number of medication dropped from 3.75 ± 0.89 to 0.89 ± 0.98. Low postoperative complications were recorded., Conclusion: During the 3-year follow-up period, penetrating deep sclerectomy presented very positive outcome. The addition of a controlled perforation of the trabeculo-Descemet's membrane in deep sclerectomy, playing the role of an early goniopuncture, seems to ensure a satisfactory outcome and is not associated with additional complications.
- Published
- 2020
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