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Background: Semipermeable membranes might be suitable for glove liners or comfort gloves in individuals with irritant contact dermatitis (ICD). Objectives: To evaluate the effects of different glove materials on inflammation and epidermal barrier impairment after experimental skin irritation. Methods: Nine test areas on the volar forearms of 24 healthy volunteers were irritated with sodium lauryl sulfate (1%) and afterward covered for 6 days (6 or 8 h/day) with semipermeable Sympatex (SYM), vinyl (OCC), combinations of vinyl with Sympatex (SYM/OCC) or cotton (COT/OCC), or left uncovered (CON). Up to day 10, measurements of transepidermal water loss (TEWL), erythema (a*), skin humidity (SH) and visual scoring (VS) were applied. Results: No significant differences in skin parameters were found between COT/OCC and SYM/OCC as well as between each of the combinations and CON. SYM, COT/OCC and SYM/OCC led to better results for most skin parameters than OCC alone. Conclusions: Occlusive material has a negative impact on skin barrier recovery and inflammation after skin irritation whereas SYM is not inferior to uncovered areas indicating good tolerability. Altogether, the data suggest that SYM is a useful alternative to COT as material for glove liners and comfort gloves in ICD patients. [ABSTRACT FROM AUTHOR]

Background: Semipermeable gloves might be an alternative to cotton gloves in management of hand dermatoses. Objectives: To compare acceptance and tolerability of gloves made of cotton or a semipermeable Sympatex membrane in patients with hand dermatoses and their effect on skin lesions when worn overnight. Methods: A total of 199 patients with work‐related symmetrical hand dermatoses were asked to wear a cotton glove (COT) on one hand and a Sympatex glove underneath a cotton glove (SYM/COT) on the other hand for 19 consecutive nights. The severity of skin lesions was regularly examined. A questionnaire on acceptance and tolerability was used in a subset of 126 patients. Results: Data on skin lesions were available for 183 participating patients (92%). The severity did not differ substantially between hands covered with SYM/COT or COT over time. Questionnaire data were available for 120 patients (95%). SYM/COT received better ratings regarding climate conditions while COT showed superiority in wearing comfort, practicality and appearance. Conclusions: Both SYM/COT and COT were well tolerated and accepted in patients with hand dermatoses. Hence, SYM/COT may serve as suitable alternative for COT as comfort gloves supporting therapeutic efforts. The observed slight differences may influence the decision when selecting the glove type. [ABSTRACT FROM AUTHOR]

Background: Glove liners (GLs) made of cotton (COT) are worn under impermeable gloves to prevent occlusion effects. Semipermeable GLs made of Sympatex (SYM) might be an alternative. Objectives: To evaluate the acceptance of GLs (COT/SYM) in health care workers (HCWs) with work‐related skin diseases (WRSDs). Methods: One hundred sixty‐one HCWs with WRSDs were asked to wear GLs in combination with occlusive gloves for 10 ±2 weeks under workplace conditions. A questionnaire was applied to compare acceptance and usability of the respective glove combinations and previously used protective gloves (PUGs). Results: A total of 120 data sets were available (SYM: n = 65, 77.4%; COT: n = 55, 71.4%). Both GLs provided a significantly lower sweating sensation, more pleasant climate, comfortable wearing experience, and moist or dry feeling on the skin compared to PUGs. SYM‐GLs performed significantly better than COT‐GLs regarding mobility of hands, sensitivity, and sense of touch. COT‐GLs were significantly better than SYM‐GLs in the categories fit, donning and doffing, and material contact. Conclusions: Both GLs did not impair work performance, were applicable in various areas of health care activities, and were preferred over PUGs. Our results indicate that SYM‐GLs are an alternative to COT‐GLs and thus may contribute to current prevention strategies. [ABSTRACT FROM AUTHOR]

Keywords: allergic contact dermatitis; case report; dithiocarbamates; gloves; nitrile/neoprene rubber; polyethylene; rubber accelerators; thiurams EN allergic contact dermatitis case report dithiocarbamates gloves nitrile/neoprene rubber polyethylene rubber accelerators thiurams 321 322 2 03/16/22 20220401 NES 220401 CASE REPORT A 44-year-old woman with atopic diathesis who worked as a cleaner of hospital beds presented with longstanding hand dermatitis. The shorter PE glove - despite having almost the same length as the disposable protective glove - tended to slip causing direct skin contact at the wrist with the protective glove containing dithiocarbamates (Figure 1C). [Extracted from the article]

Background Objectives Methods Results Conclusions Comfort gloves are used in the management of hand dermatoses.To compare the acceptance and tolerability of comfort gloves made of different materials in patients with hand dermatoses and their effects on skin lesions.In a prospective multicenter study, 284 patients with hand dermatoses were invited to wear either a cotton glove (COT) or a semipermeable Sympatex glove underneath a cotton glove (SYM/COT) for two subsequent phases of 19 consecutive nights each. A total of 88 controls were asked not to wear any comfort gloves overnight. The severity of skin lesions over time was examined. Questionnaires were used to assess health‐related quality of life (HRQoL) and acceptance and tolerability of the gloves.The hand dermatoses improved in all groups. No substantial intergroup differences regarding severity and HRQoL were observed. SYM/COT received better ratings regarding climate conditions and tactility while COT showed superiority in fit, wearing comfort, and practicality.We confirmed that SYM/COT and COT are well tolerated and accepted suggesting that SYM/COT is a good alternative for COT as comfort gloves in patients with hand dermatoses. Individual requirements, needs, and preferences may direct the material choice. [ABSTRACT FROM AUTHOR]