1. Bifunctional and highly sensitive electrochemical non-enzymatic glucose and hydrogen peroxide biosensor based on NiCo 2 O 4 nanoflowers decorated 3D nitrogen doped holey graphene hydrogel.
- Author
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Lu Z, Wu L, Zhang J, Dai W, Mo G, and Ye J
- Subjects
- Blood Glucose analysis, Catalysis, Electrodes, Humans, Nitrogen chemistry, Photoelectron Spectroscopy, Reproducibility of Results, Spectrum Analysis, Raman, X-Ray Diffraction, Biosensing Techniques methods, Cobalt chemistry, Electrochemical Techniques methods, Glucose analysis, Graphite chemistry, Hydrogels chemistry, Hydrogen Peroxide analysis, Nanocomposites chemistry, Nickel chemistry, Oxides chemistry
- Abstract
In this work, a simple strategy for fabricating a 3D nitrogen doped holey graphene hydrogel decorated with NiCo
2 O4 nanoflowers (NHGH/NiCo2 O4 ) via a one-pot hydrothermal method with subsequent calcination is reported for the first time. The novel NHGH/NiCo2 O4 nanocomposites featured high electrical conductivity, large and accessible surface areas, abundant active sites, and excellent electrocatalytic performance. Considering the excellent catalytic activity of NiCo2 O4 , a sensitive and bifunctional electrochemical non-enzymatic biosensor was established for the determination of glucose and hydrogen peroxide (H2 O2 ). The obtained biosensor exhibited wide linear ranges (glucose: 0.005-10.95 mM; H2 O2 : 1-510 μM) and a low detection limits (glucose: 0.39 μM; H2 O2 : 0.136 μM) in alkaline solution (S/N = 3). Excellent electrocatalytic activity of this sensor was ascribed to the synergistic effects of the hybrid structure between the NiCo2 O4 nanoflowers and NHGH. Furthermore, the sensitive biosensor also exhibited high selectivity and could be applied to determine glucose in real blood samples. Taken together, the results reveal that the proposed hybrid nanocomposite could be a promising electrochemical biosensor., (Copyright © 2019 Elsevier B.V. All rights reserved.)- Published
- 2019
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