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B Tumor Starvation Therapy b In article number 2103534 by Zhenzhong Zhang, Junjie Liu, Jinjin Shi, and co-workers, a "nano-enabled energy interrupter"-initiated novel paradigm of tumor starvation therapy is proposed. Nano-enabled Tumor Systematic Energy Exhaustion via Zinc (II) Interference Mediated Glycolysis Inhibition and Specific GLUT1 Depletion (Adv. Sci. 7/2022) The energy interrupter shows a preferential tumor systemic energy exhaustion without obvious side effects by synergizing the "Zn SP 2+ sp interference"-mediated glycolysis inhibition and Zn SP 2+ sp -activating GLUT1 (glucose transporter 1) tumor specific depletion. [Extracted from the article]