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A series of fluorescein-based β-C-glycosyl ketones were synthesized through aldol condensation of β-C-glycosyl ketones with fluorescein monoaldehyde under ambient reaction conditions in good yields. Formation of the expected product has been confirmed through different spectral techniques. Fluorescein-based β-C-glycosides show moderate anti-oxidant activities with maximum inhibitory activity of 60%., (Copyright © 2013 Elsevier Ltd. All rights reserved.)

Facile glycosylation of a fluorescein diol derivative with per-O-acetyl/benzoyl sugar derivatives using BF(3)·Et(2)O catalyst resulted in the formation of the expected glycosides in 54-66% yield. The biological screening of the glycosides against different microbes shows good inhibitory activity. The antioxidant activity of the fluorescein-based glycosides shows remarkable inhibition (IC(50) ∼80%)., (Copyright © 2011 Elsevier Ltd. All rights reserved.)

Rhodamine based β-C-glycosides were synthesized through aldol condensation of β-C-glycosylketones with rhodamine aldehyde under ambient reaction conditions in good yields. Formation of the expected product has been confirmed through different spectral techniques. Gelation properties of these compounds were studied in regard to their molecular structure by HRTEM, FESEM. DSC, rheological and PXRD techniques. [ABSTRACT FROM AUTHOR]

• Rhodamine-GFFYE-CS-EE self-assembly to supramolecular hydrogel via the reduction of glutathione (GSH) • Cytotoxicity of TRDM-F in human Hela cells • Ferrocene-rhodamine receptor linked by a pyridine moiety • Antibacterial activity of the dendrimer by agar diffusion method • Rheological property of the Rhodamine- C -glycoside • Live cell imaging of SiR-BACE1 • Structure of R6G-graphene for cation- π interaction [Display omitted] Rhodamine dyes are widely used as fluorescent probes owing to their high fluorescence quantum yield and photo-stability. Although minute quantities of heavy metal ions are necessary for the living organisms. They play vital roles in biological, environmental, and chemical systems, but excessive amounts have a damaging effect on the organisms. The development of chemo-sensor is important for sensing and recognizing environmentally and biologically applications. The probes are invaluable for the dynamics of gene expression, protein expression, and molecular interactions in complex living systems. They are often used as scaffolds in biological labeling and turn-on fluorescence imaging. This review is a collection of research articles discussed in the context of the structural features of rhodamine derivatives organized according to their fluorescent core scaffold and with their representative applications. Rhodamine dyes are widely used as fluorescent probes owing to their high fluorescence quantum yield and photo-stability. Although minute quantities of heavy metal ions are necessary for the living organisms. They play vital roles in biological, environmental, and chemical systems, but excessive amounts have a damaging effect on the organisms. The development of chemo-sensor is important for sensing and recognizing environmentally and biologically applications. The probes are invaluable for the dynamics of gene expression, protein expression, and molecular interactions in complex living systems. They are often used as scaffolds in biological labeling and turn-on fluorescence imaging. This review is a collection of research articles discussed in the context of the structural features of rhodamine derivatives organized according to their fluorescent core scaffold and with their representative applications. [ABSTRACT FROM AUTHOR]

• Labeling reaction of reducing saccharides with FTSC and its application to living cells. • Antioxidant and Anti-cancer activities of fluorescein glycosides. • Synthesis of Fluorescein Grafted Cellulose Nanocrystals with Amino Acid Space. • Fluorescein chemosensors have been developed for selective fluorescence detection of TNP when excited by the visible light. • Photoactivatable fluorescein sensors for detecting mobile Zinc. • Thiol-specific fluorescent probe for Zebrafish imaging. Biosensors are analytical devices specifically designed to convert biological response into electrochemical, optical, acoustic and electronic signal. Generally, the principle and concept of biosensors facilitate the fabrication of advanced devices displaying potential biological applications. In particular, the Fluorescein based probes display a significant role in the development of optical biosensors. This review focus on the current advances in the fluorescence probes, including the development and challenges to enhance the sensing properties in the field of biosensors for next generation biological applications. Image, graphical abstract [ABSTRACT FROM AUTHOR]