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Start Over Author "Yang, Jiong-Peng" Topic gram-positive bacteria
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1. Synthesis, Structure, and Antibacterial Activities of Diterpenoid Isosteviol-Derived Alkenyl Ethers.

Author

Liu, Cong-Jun, Yu, Zi-Yue, Min, Yu-Tao, Zhang, Jun-Wei, Zhang, Jun, Lu, Zhen-Wei, Yang, Jiong-Peng, and Wang, Yu-Fei

Subjects
ANTIBACTERIAL agents, GRAM-negative bacteria, ETHERS, GRAM-positive bacteria
Abstract

A series of novel isosteviol-derived alkenyl ethers were synthesized and structurally characterized by IR, NMR, and HR-MS. The tested compounds are more sensitive to Gram-positive bacteria than to Gram-negative bacteria. In particular, compound 5 exhibited better bacteriostatic activity against B. subtilis with a minimum inhibitory concentration of 2.403 mM, whereas compounds 8 and 10 selectively inhibited the S. aureus strain. [ABSTRACT FROM AUTHOR]

Published
2022
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