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We report a rapid, efficient, economic, environmentally benign, and easy to scale-up method for the synthesis of phosphonamide derivatives using ultrasound irradiation, under catalyst and solvent-free conditions starting from the corresponding amine and phenyl phosphonic dichloride. The reaction was achieved in excellent isolated yield in a short reaction time at room temperature. The structures of the synthesized compounds are confirmed by elemental analysis as well as by IR and 1H, 13C, 31P NMR spectroscopic data and mass spectrometry. [ABSTRACT FROM AUTHOR]

An efficient protocol was developed for the synthesis ofN-sulfonylimines under environment friendly conditions. Ultrasonic energy was employed to obtain the desired products in excellent yields with high purity under solvent- and catalyst-free conditions. The synthesis of newN-sulfonylimines was accomplished from variousN-sulfonamides and benzaldehyde. The structures of the synthesized compounds are confirmed by elemental analysis as well as by1H,13C NMR spectral data, IR and MS. [ABSTRACT FROM AUTHOR]

Various N-acylamines (I), N-acylaminoester ((S)-IV), N-acylaminoalcohols ((S)-VIII), and N-acylsulfonamides (X) are efficiently phosphorylated with trialkylphosphite under ultrasound irradiation conditions furnishing corresponding amidophosphonates in high yield. [ABSTRACT FROM AUTHOR]