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Post-vaccine olfactory and gustatory disorders are very rare and were reported in patients who received influenza vaccines. In this article, we report 6 cases of post-coronavirus disease 2019 (COVID-19) vaccine olfactory and gustatory disorders in patients with negative nasal swabs. Precisely, olfactory and gustatory dysfunctions were reported in 5 and 1 patients, respectively. Sense disorders occurred after the first injection of AstraZeneca (n = 4) or the second injection of Pfizer (n = 2) vaccines. In 4 cases, the olfactory or gustatory disorder was confirmed with psychophysical evaluations. The duration of chemosensory dysfunction ranged from 4 to 42 days. None of the patient reported mid- or long-term olfactory or gustatory disorder. The occurrence of olfactory and gustatory dysfunctions in adults benefiting from COVID-19 vaccines is still rare but has to be known by otolaryngologists. [ABSTRACT FROM AUTHOR]

Keywords: Smell; Taste; Anosmia; Hyposmia; Gustatory; Dysgeusia; Loss; COVID-19; Coronavirus; Dear editor EN Smell Taste Anosmia Hyposmia Gustatory Dysgeusia Loss COVID-19 Coronavirus Dear editor 2397 2398 2 07/07/20 20200801 NES 200801 Jerome R. Lechien and Julien W. Hsieh contributed to the paper and are joint as co-first authors. Dear Editor, We thank Dr Bigiani [[1]] for this letter entitled "Gustatory dysfunctions in COVID-19 patients: possible involvement of taste renin-angiotensin system (RAS)" which is related to our paper [[2]]. References 1 Bigiani A. Gustatory dysfunctions in COVID-19 patients: possible involvement of taste renin-angiotensin system (RAS). [Extracted from the article]

Making scents of loss of taste in COVID-19: Is self-reported loss of taste due to olfactory dysfunction? Three clinical presentations were accepted for patient eligibility: isolated sudden loss of smell, isolated sudden loss of taste, or concomitant sudden loss of smell and taste. These results support the idea that most patients with COVID-19 tend to unconsciously conflate taste loss and olfactory loss, even when taste function is clearly defined to them beforehand as only referring to the perception of sweet, salty, sour, and bitter tastes. [Extracted from the article]