1. Hair Growth in a Patient with Alopecia Areata on Tocilizumab
- Author
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Chloe J. Walker, James T. Pathoulas, Maryanne M. Senna, Kelly E. Flanagan, and Isabel Pupo Wiss
- Subjects
Autoimmune disease ,medicine.medical_specialty ,medicine.drug_class ,business.industry ,Dermatology ,Progressive alopecia ,Alopecia areata ,medicine.disease ,Monoclonal antibody ,Hair growth ,chemistry.chemical_compound ,Tocilizumab ,Hair loss ,chemistry ,Novel Insights from Clinical Practice ,Concomitant ,medicine ,business - Abstract
Introduction: Tocilizumab (TCZ), a recombinant humanized antihuman monoclonal antibody targeting interleukin-6 (IL-6) signaling, is often utilized in the management of autoimmune disease. Few reports have demonstrated hair growth changes in patients on TCZ. Case Presentation: Herein, we review the literature and report a 21-year-old woman with progressive alopecia areata (AA) presenting with AA improvement while on TCZ for concomitant posterior uveitis. Discussion: Our case demonstrates the potential ability of TCZ to disrupt IL-6 signaling involved in AA, leading to hair loss and regrowth.
- Published
- 2021