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Giant landslides, which usually have volumes up to several tens of km(3), tend to be related to mountainous reliefs such as fault scarps or thrust fronts. The western flank of the Precordillera in southern Peru and northern Chile is characterized by the presence of such mega-landslides. A good example is the Latagualla Landslide (19 degrees 15'S), composed of -5.4 km(3) of Miocene ignimbritic rock blocks located next to the Moquella Flexure, a structure resulting from the propagation of a west-vergent thrust blind fault that borders the Precordillera of the Central Depression. The landslide mass is very well preserved, allowing reconstitution of its movement and evolution in three main stages. The geomorphology of the landslide indicates that it preceded the incision of the present-day valleys during the late Miocene. Given the local geomorphological conditions 8-9 Ma ago (morphology, slopes and probably a high water table), large-magnitude earthquakes could have provided destabilization forces enough to cause the landslide. On the other hand, present seismic forces would not be sufficient to trigger Such landslides; therefore the hazard related to them in the region is low.