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68 results on '"Cardiovascular diseases -- Risk factors -- Prevention -- Research"'

1. Reports on Cardiovascular Diseases and Conditions Findings from Radboud University Nijmegen Provide New Insights (Identification of Cardiovascular Patient Groups At Risk for Poor Medication Adherence a Cluster Analysis)

Subjects
Medical research -- Health aspects, Medicine, Experimental -- Health aspects, Patient compliance -- Research -- Health aspects, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Cardiac patients -- Research -- Health aspects, Physical fitness -- Health aspects -- Research, Health
Abstract

2021 OCT 2 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Current study results on Cardiovascular Diseases and Conditions have been published. According [...]

Published
2021

2. Findings from Public Health England in the Area of Cardiovascular Diseases and Conditions Described (Effectiveness of Digital Interventions for Reducing Behavioral Risks of Cardiovascular Disease In Nonclinical Adult Populations: Systematic ...)

Subjects
Medical research -- Reports, Medicine, Experimental -- Reports, Health -- Reports -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Health
Abstract

2021 JUN 26 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- New research on Cardiovascular Diseases and Conditions is the subject of a [...]

Published
2021

3. Autonomous University Madrid Researchers Update Understanding of Cardiovascular Diseases and Conditions (Application of a Lifestyle-Based Score to Predict Cardiovascular Risk in African Americans: The Jackson Heart Study)

Subjects
Medical research, Medicine, Experimental, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Physical fitness -- Research, African Americans -- Research, Health
Abstract

2021 JUN 19 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- New research on cardiovascular diseases and conditions is the subject of a [...]

Published
2021

4. New Cardiovascular Diseases and Conditions Study Findings Recently Were Reported by Researchers at University of Padua (Cardiovascular Risk Profiles and 20-year Mortality In Older People: Gender Differences In the Pro.va Study)

Subjects
Women -- Health aspects, Medical research -- Reports, Medicine, Experimental -- Reports, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Health, Women's issues/gender studies, University of Padua -- Reports
Abstract

2021 MAY 20 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- A new study on Cardiovascular Diseases and Conditions is now available. According to news [...]

Published
2021

5. Researchers from University of Kentucky Describe Findings in Cardiovascular Diseases and Conditions (Reconsidering the Polypill for Management of Cardiovascular Risk Factors In Underserved Patients)

Subjects
Medical research -- Reports, Medicine, Experimental -- Reports, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Physical fitness -- Research -- Reports, Hydrochlorothiazide -- Research, Health, University of Kentucky -- Reports
Abstract

2021 APR 3 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Research findings on Cardiovascular Diseases and Conditions are discussed in a new [...]

Published
2021

6. New York University (NYU) Langone Health Researchers Describe New Findings in Cardiovascular Diseases and Conditions (A practice facilitation-guided intervention in primary care settings to reduce cardiovascular disease risk: a cost analysis)

Subjects
Medical research -- Economic aspects, Medicine, Experimental -- Economic aspects, Family medicine -- Economic aspects -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Physical fitness -- Economic aspects -- Research, Health, New York University
Abstract

2021 FEB 27 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Researchers detail new data in cardiovascular diseases and conditions. According to news [...]

Published
2021

7. Studies from Bispebjerg and Frederiksberg Hospitals Provide New Data on Obesity (Uncarboxylated Matrix Gla-protein: a Biomarker of Vitamin K Status and Cardiovascular Risk)

Subjects
Vitamins -- Research, Medical research, Medicine, Experimental, Obesity -- Prevention -- Risk factors -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Physical fitness -- Research, Health
Abstract

2021 FEB 13 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators discuss new findings in Nutritional and Metabolic Diseases and Conditions - [...]

Published
2021

8. Recent Studies from University of Canberra Add New Data to Cardiovascular Diseases and Conditions (A smartphone app for sedentary behaviour change in cardiac rehabilitation and the effect on hospital admissions: the ToDo-CR randomised ...)

Subjects
Medical research -- Reports, Medicine, Experimental -- Reports, Hospitals -- Admission and discharge, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Physical fitness -- Research -- Reports, Health, University of Canberra -- Reports
Abstract

2021 JAN 2 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- New study results on cardiovascular diseases and conditions have been published. According [...]

Published
2021

9. Cardiovascular safety of medications for type 2 diabetes mellitus

Author

Butler, Javed

Subjects
Type 2 diabetes -- Risk factors -- Research -- Drug therapy -- Safety and security measures -- Complications and side effects -- Patient outcomes, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Health
Abstract

INTRODUCTION Type 2 diabetes mellitus (T2DM) is an independent risk factor for cardiovascular disease, conferring about a twofold greater risk for a wide range of cardiovascular diseases. (1) Cardiovascular disease [...]

Published
2017

10. New Findings on Atherosclerosis from University Hospital Center Montreal Summarized (Predicting Risk of Atherosclerotic Cardiovascular Disease Using Pooled Cohort Equations In Older Adults With Frailty, Multimorbidity, and Competing Risks)

Subjects
Atherosclerosis -- Prevention -- Risk factors -- Research, Physical fitness -- Research -- Reports, Elderly -- Research -- Reports, Medical research -- Reports, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Health
Abstract

2020 OCT 31 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- A new study on Cardiovascular Diseases and Conditions - Atherosclerosis is now [...]

Published
2020

11. New Sports Medicine Findings Has Been Reported by Researchers at University Heart Center Zurich (Effects of active commuting on cardiovascular risk factors: GISMO-a randomized controlled feasibility study)

Subjects
Chronic diseases -- Research -- Prevention -- Risk factors, Physical fitness -- Research -- Reports, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Health
Abstract

2020 SEP 12 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators publish new report on Health and Medicine - Sports Medicine. According [...]

Published
2020

12. New Findings in Obesity Described from Bispebjerg and Frederiksberg Hospitals (Uncarboxylated Matrix Gla-protein: a Biomarker of Vitamin K Status and Cardiovascular Risk)

Subjects
Obesity -- Prevention -- Risk factors -- Research, Physical fitness -- Research -- Reports, Vitamins -- Research -- Reports, Medical research -- Reports, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Health
Abstract

2020 SEP 12 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators publish new report on Nutritional and Metabolic Diseases and Conditions - [...]

Published
2020

13. Capital Medical University Researchers Update Knowledge of Cardiovascular Diseases and Conditions (Platelet counts are associated with arterial stiffness in Chinese Han population: a longitudinal study)

Subjects
Mediation -- Research, Atherosclerosis -- Prevention -- Risk factors -- Research, Physical fitness -- Research, Medical research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Health
Abstract

2020 AUG 22 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Research findings on cardiovascular diseases and conditions are discussed in a new [...]

Published
2020

14. Findings from Centro Hospitalar e Universitario de Coimbra in Cardiovascular Diseases and Conditions Provides New Insights (A 10- and 15-year performance analysis of ESC/EAS and ACC/AHA cardiovascular risk scores in a Southern European cohort)

Subjects
Physical fitness -- Research, Medical research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Health
Abstract

2020 JUL 4 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Researchers detail new data in Cardiovascular Diseases and Conditions. According to news [...]

Published
2020

15. University of Greifswald Researchers Reveal New Findings on Cardiovascular Diseases and Conditions (Do sociodemographic variables and cardiometabolic risk factors moderate the mere-measurement effect on physical activity and sedentary time?)

Subjects
Physical fitness -- Research, Medical research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Health
Abstract

2020 JUN 27 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Researchers detail new data in cardiovascular diseases and conditions. According to news [...]

Published
2020

16. Federal University Sergipe Researchers Describe Findings in Exercise Therapy (Effects of 12 Weeks of Resistance Training on Cardiovascular Risk Factors in School Adolescents)

Subjects
Physical fitness -- Research, Youth -- Research, Exercise therapy -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Weight training -- Research, Obesity, Physical therapy, Editors, Health
Abstract

2020 MAY 30 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Researchers detail new data in exercise therapy. According to news originating from [...]

Published
2020

17. Reports from Columbia University Add New Data to Findings in Cardiovascular Diseases and Conditions (Reducing Cardiovascular Disease Risk In Women Beyond Statin Therapy: New Insights 2020)

Subjects
Fenofibrate -- Research, Physical fitness -- Research, Statins -- Research, Medical research, Icosapent ethyl -- Research, Cardiovascular agents -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Obesity, Antilipemic agents, Clinical trials, Editors, Diseases, Health, Columbia University
Abstract

2020 MAY 16 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Current study results on Cardiovascular Diseases and Conditions have been published. According [...]

Published
2020

18. Findings from Imperial College London in Cardiovascular Diseases and Conditions Reported (Perspective: the Application of a Priori Diet Quality Scores To Cardiovascular Disease Risk-a Critical Evaluation of Current Scoring Systems)

Subjects
Physical fitness -- Health aspects -- Research -- Reports, Medical research -- Reports -- Health aspects, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Diet -- Health aspects -- Reports -- Research, Obesity, Finance, Editors, Women, Diseases, Health, University of London. Imperial College of Science and Technology -- Reports
Abstract

2020 MAY 2 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Research findings on Cardiovascular Diseases and Conditions are discussed in a new [...]

Published
2020

19. Effects of Mediterranean-style diet on glycemic control, weight loss and cardiovascular risk factors among type 2 diabetes individuals: a meta-analysis

Author

Huo, R., Du, T., Xu, Y., Xu, W., Chen, X., Sun, K., and Yu, X.

Subjects
Mediterranean diet -- Health aspects -- Research, Type 2 diabetes -- Diet therapy -- Complications and side effects -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Food/cooking/nutrition, Health
Abstract

BACKGROUND/OBJECTIVES: Studies suggest that the Mediterranean-style diet (MSD) may improve glucose metabolism in patients with type 2 diabetes (T2D), but the results are inconsistent. We conducted a meta-analysis of randomized controlled trials (RCTs) to explore the effects of MSD on glycemic control, weight loss and cardiovascular risk factors in T2D patients. SUBJECTS/METHODS: We performed searches of EMBASE, Cochrane Library and PubMed databases up to February 2014. We included RCTs that compared the MSD with control diets in patients with T2D. Effect size was estimated as mean difference with 95% confidence interval (CI) by using random effect models. RESULTS: The meta-analysis included nine studies with 1178 patients. Compared with control diets, MSD led to greater reductions in hemoglobin A1c (mean difference, -0.30;95% CI, -0.46 to -0.14), fasting plasma glucose (-0.72 mmol/l; CI, -1.24 to -.21), fasting insulin (-0.55 [micro]U/ml; CI,-0.81 to -0.29), body mass index (-0.29 kg/[m.sup.2]; CI, -0.46 to -0.12) and body weight (-0.29 kg; CI, -0.55 to -0.04). Likewise, concentrations of total cholesterol and triglyceride were decreased (-0.14 mmol/l; CI, -0.19 to -0.09 and -0.29 mmol/l; CI, -0.47 to -0.10, respectively), and high-density lipoprotein was increased (0.06 mmol/l; CI, 0.02 to 0.10). In addition, MSD was associated with a decline of 1.45 mm Hg (CI, -1.97 to -0.94) for systolic blood pressure and 1.41 mm Hg (CI, -1.84 to -0.97) for diastolic blood pressure. CONCLUSIONS: The present meta-analysis provides evidence that MSD improves outcomes of glycemic control, body weight and cardiovascular risk factors in T2D patients. European Journal of Clinical Nutrition (2015) 69, 1200-1208; doi: 10.1038/ejcn.2014.243; published online 5 November 2014, INTRODUCTION Type 2 diabetes (T2D) is a global epidemic and a main threat to human health. It is estimated that about 552 million cases worldwide will suffer from T2D by [...]

Published
2015
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20. Findings from School of Allied Health in the Area of Cardiovascular Diseases and Conditions Reported [Effect of high polyphenol extra virgin olive oil on markers of cardiovascular disease risk in healthy Australian adults (OLIVAUS): A protocol ...]

Subjects
Olive oil -- Health aspects, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Obesity, Physical fitness, Clinical trials, Australians, Editors, Medical research, Adults, Health
Abstract

2019 MAY 4 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Current study results on Cardiovascular Diseases and Conditions have been published. According [...]

Published
2019

21. Phosphate is a vascular toxin

Author

Shroff, Rukshana

Subjects
Chronic kidney failure -- Complications and side effects -- Genetic aspects -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Phosphates -- Health aspects -- Measurement, Health
Abstract

Elevated phosphate (P) levels are seen in advanced renal failure and, together with dysregulated calcium, parathyroid hormone and vitamin D levels, contribute to the complex of chronic kidney disease-mineral and bone disease (CKD-MBD). Converging evidence from in vitro, clinical and epidemiological studies suggest that increased P is associated with vascular calcification and mortality. When vessels are exposed to high P conditions in vitro, they develop apoptosis, convert to bone-like cells and develop extensive calcification. Clinical studies in children on dialysis show that high P is associated with increased vessel wall thickness, arterial stiffness and coronary calcification. Epidemiological studies in adult dialysis patients demonstrate a significant and independent association between raised P and mortality. Importantly, raised P is associated with cardiovascular changes even in pre-dialysis CKD, and also in subjects with normal renal function but high P. All P binders can effectively reduce serum P, and this decrease is linked to improved survival. Raised serum P triggers the release of fibroblast growth factor 23 (FGF-23), which has the beneficial effect of increasing P excretion in early CKD, but is increased several 1,000-fold in dialysis, and may be an independent cardiovascular risk factor. Both FGF-23 and its co-receptor Klotho may have direct effects on the vasculature leading to calcification. Fascinatingly, disturbances in FGF-23-Klotho and raised P have also been associated with premature aging. These data suggest that high P levels have adverse vascular effects and that maintaining the serum P levels in the normal range reduces cardiovascular risk and mortality. Keywords Phosphate * Chronic kidney disease * Cardiovascular disease * Vascular calcification * Dialysis, Introduction Phosphorus is an essential element that forms a key component of nucleic acids and cell membranes and is required for maintaining the normal homeostatic control of the cell, including [...]

Published
2013
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22. Effects of the herbal medicine composition 'Saiko-ka-ryukotsu-borei-To' on the function of endothelial progenitor cells in hypertensive rats

Author

Iijima, Hiroshi, Daikonya, Akihiro, Satoshi, Takamatsu, Kanno, Ai, Magariyama, Kayoko, Yoshikawa, Kazuki, Takamiya, Tomoko, Ueda, Yukiko, Yakubo, Shuji, Matsumoto, Taro, Ueno, Takahiro, Yamori, Yukio, Fukuda, Noboru, and Kitanaka, Susumu

Subjects
Medicine, Botanic -- Health aspects -- Chemical properties -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Medicine, Herbal -- Health aspects -- Chemical properties -- Research, Epithelial cells -- Health aspects -- Research, Hypertension -- Care and treatment -- Research, Biological sciences, Health, Science and technology
Abstract

ARTICLE INFO Keywords: Saiko-ka-ryukotsu-borei-To Endothelial progenitor cell Oxidative stress IL-6 Spontaneously hypertensive rat ABSTRACT Endothelial progenitor cells (EPCs) are known to repair vascular injuries. Recent studies suggest that Saiko-ka-ryukotsu-borei-To (SKRBT), [...]

Published
2013

23. Hypertension and target organ damage in obese children

Author

Stabouli, Stella and Kotsis, Vasilios

Subjects
Multiple organ failure -- Risk factors -- Prevention -- Research, Obesity in children -- Care and treatment -- Complications and side effects -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Hypertension -- Risk factors -- Prevention -- Research, Health, Prevention, Care and treatment, Complications and side effects, Research, Risk factors
Abstract

Author(s): Stella Stabouli [sup.[[dagger]]] [sup.1] , Vasilios Kotsis [sup.2] Childhood obesity has become an important health issue worldwide [sup.[1]] . It is associated with several risk factors for later cardiovascular [...]

Published
2009
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24. Has the time come to replace mercury sphygmomanometers by automated devices for measuring blood pressure in children?

Author

Huerta, Samuel Flores, Klünder, Miguel Klünder, and Bravo, Patricia Medina

Subjects
Sphygmomanometer -- Usage -- Health aspects, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Blood pressure -- Measurement, Health, Prevention, Usage, Research, Risk factors, Health aspects
Abstract

Blood pressure assessment in children has acquired special relevance to prevent cardiovascular diseases later in life, therefore, there is a need to implement appropriate measurement techniques and suitable and accurate support instruments. Traditionally, blood pressure has been measured with mercury sphygmomanometers using the auscultatory technique and, at present, it is even considered to be the gold standard. Nevertheless, this device has a number of measurement pitfalls that, combined with its potential ecological risk owing to accidental mercury pollution, has stimulated the development and design of automated devices, which mainly use the oscillometric method for blood pressure measurement. Automated devices are mercury free and they have abolished some measurement procedures errors, mainly those related to the observer. However, these instruments are not better than mercury sphygmomanometers when accuracy parameters regarding blood pressure measurement are taken into consideration; on the other hand, at present, there are scarce validated automated devices for children. It is expected that mercury sphygmomanometers will be superseded in the near future, but only if automated devices are validated by international protocols and, of course, also considering the fact that they will be affordable., Author(s): Samuel Flores Huerta [sup.[[dagger]]] [sup.1] , Miguel Klünder Klünder [sup.2] , Patricia Medina Bravo [sup.3] Keywords: Keywords accuracy; auscultation; automated devices; blood pressure; children; mercury sphygmomanometer; oscillometric; validation The [...]

Published
2009
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25. Study Data from University of Palermo Update Understanding of Atherosclerosis [Electrocardiographic Abnormalities, Preclinical Carotid Atherosclerosis and Cardiovascular Risk In an Apparently Healthy Real-world Population Data From the 'no ...]

Subjects
Medical research, Medicine, Experimental, Electrocardiography -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Electrocardiogram -- Research, Atherosclerosis -- Prevention -- Risk factors -- Research, Health
Abstract

2022 JAN 3 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity & Diabetes Week -- Current study results on Cardiovascular Diseases and Conditions - Atherosclerosis have been published. [...]

Published
2022

26. The effect of intensive glucose lowering on lipoprotein particle profiles and inflammatory markers in the Veterans Affairs Diabetes Trial (VADT)

Author

Koska, Juraj, Saremi, Aramesh, Bahn, Gideon, and Reaven, Shizuya Yamashita. Peter D.

Subjects
Diabetes therapy -- Health aspects -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Type 2 diabetes -- Complications and side effects -- Prognosis -- Research, Health
Abstract

OBJECTIVE--Intensive glucose-lowering therapy (INT) did not reduce macrovascular events in the recent randomized trials, possibly because it did not improve or worsen other traditional or novel cardiovascular risk factors. RESEARCH [...]

Published
2013
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27. High- and moderate-intensity training normalizes ventricular function and mechanoenergetics in mice with diet-induced obesity

Author

Hafstad, Anne D., Lund, Jim, Hadler-Olsen, Elin, Hoper, Anje C., Larsen, Terje S., and Aasum, Ellen

Subjects
Exercise -- Physiological aspects -- Research, Obesity -- Complications and side effects -- Research, Diabetes -- Complications and side effects -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Health
Abstract

Although exercise reduces several cardiovascular risk factors associated with obesity/diabetes, the metabolic effects of exercise on the heart are not well-known. This study was designed to investigate whether high-intensity interval training (HIT) is superior to moderate-intensity training (MIT) in counteracting obesity-induced impairment of left ventricular (LV) mechanoenergetics and function. C57BL/6J mice with diet-induced obesity (DIO mice) displaying a cardiac phenotype with altered substrate utilization and impaired mechanoenergetics were subjected to a sedentary lifestyle or 8-10 weeks of isocaloric HIT or MIT. Although both modes of exercise equally improved aerobic capacity and reduced obesity, only HIT improved glucose tolerance. Hearts from sedentary DIO mice developed concentric LV remodeling with diastolic and systolic dysfunction, which was prevented by both HIT and MIT. Both modes of exercise also normalized LV mechanical efficiency and mechanoenergetics. These changes were associated with altered myocardial substrate utilization and improved mitochondrial capacity and efficiency, as well as reduced oxidative stress, fibrosis, and intracellular matrix metalloproteinase 2 content. As both modes of exercise equally ameliorated the development of diabetic cardiomyopathy by preventing LV remodeling and mechanoenergetic impairment, this study advocates the therapeutic potential of physical activity in obesity-related cardiac disorders., Obesity, sedentary lifestyle, and reduced aerobic capacity are known predictors of heart failure and a major challenge to the health care system of the Western society (1,2). In addition to [...]

Published
2013
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28. Maternal and neonatal circulating markers of metabolic and cardiovascular risk in the Metformin in Gestational Diabetes (MiG) trial: responses to maternal metformin versus insulin treatment

Author

Barrett, Helen L., Gatford, Kathryn L., Houda, Candce M., De Blasio, Miles J., McIntyre, H. David, Callaway, Leonie K., Nitert, Marloes Dekker, Coat, Suzette, Owens, Julie A., Hague, William M., and Rowan, Janet A.

Subjects
Diabetes in pregnancy -- Drug therapy -- Prognosis -- Research, Metformin -- Dosage and administration -- Complications and side effects -- Comparative analysis, Insulin -- Dosage and administration -- Complications and side effects -- Comparative analysis, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Health
Abstract

OBJECTIVE--This study was designed to compare glucose, lipids, and C-reactive protein (CRP) in women with gestational diabetes mellitus treated with metformin or insulin and in cord plasma of their offspring [...]

Published
2013
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29. Association between physical activity and risk of all-cause mortality and cardiovascular disease in patients with diabetes: a meta-analysis

Author

Kodama, Satoru, Tanaka, Shiro, Heianza, Yoriko, Fujihara, Kazuya, Horikawa, Chika, Shimano, Hitoshi, Saito, Kazumi, Yamada, Nobuhiro, Ohashi, Yasuo, and Sone, Hirohito

Subjects
Exercise -- Health aspects -- Research, Mortality -- Prevention -- Research -- Japan, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Diabetics -- Health aspects -- Research, Health
Abstract

OBJECTIVE--The association between habitual physical activity (PA) and lowered risk of all-cause mortality (ACM) and cardiovascular disease (CVD) has been suggested in patients with diabetes. This meta-analysis summarizes the risk [...]

Published
2013
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30. Effect of combination therapy with fenofibrate and simvastatin on postprandial lipemia in the ACCORD Lipid trial

Author

Reyes-Soffer, Gissette, Ngai, Colleen I., Lovato, Laura, Karmally, Wahida, Ramakrishnan, Rajasekhar, Holleran, Stephen, and Ginsberg, Henry N.

Subjects
Simvastatin -- Dosage and administration -- Complications and side effects, Fenofibrate -- Dosage and administration -- Complications and side effects, Lipemia -- Causes of -- Complications and side effects -- Drug therapy -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Health
Abstract

OBJECTIVE--The Action to Control Cardiovascular Risk in Diabetes lipid study (ACCORD Lipid), which compared the effects of simvastatin plus fenofibrate (FENO-S) versus simvastatin plus placebo (PL-S) on cardiovascular disease outcomes, [...]

Published
2013
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31. Benefits of early hypertension control on cardiovascular outcomes in patients with diabetes

Author

O'Connor, Patrick J., Vazquez-Benitez, Gabriela, Schmittdiel, Jule A., Parker, Emily D., Trower, Nicole K., Desai, Jay R., Margolis, Karen L., and Magid, David J.

Subjects
Cardiovascular diseases -- Risk factors -- Prevention -- Research, Diabetics -- Health aspects -- Research, Hypertension -- Complications and side effects -- Care and treatment -- Research, Health
Abstract

OBJECTIVE--To assess the impact of early hypertension (HT) control on occurrence of subsequent major cardiovascular events in those with diabetes and recent-onset HT. RESEARCH DESIGN AND METHODS--Study subjects were 15,665 [...]

Published
2013
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32. Investigators at Wake Forest University Report Findings in Atherosclerosis [High-sensitivity C-reactive Protein Modifies the Cardiovascular Risk of Lipoprotein(A) Multi-ethnic Study of Atherosclerosis]

Subjects
Medical research -- Reports, Medicine, Experimental -- Reports, Cardiovascular diseases -- Risk factors -- Prevention -- Research, C-reactive protein -- Research -- Reports, Lipoprotein A -- Research -- Reports, Atherosclerosis -- Prevention -- Risk factors -- Research, Health
Abstract

2021 OCT 8 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Research findings on Cardiovascular Diseases and Conditions - Atherosclerosis are discussed in a [...]

Published
2021

33. Vascular dysfunction in experimental diabetes is improved by pentaerithrityl tetranitrate but not isosorbide-5-mononitrate therapy

Author

Schuhmacher, Swenja, Oelze, Matthias, Bollmann, Franziska, Kleinert, Hartmut, Otto, Christian, Heeren, Tjebo, Steven, Sebastian, Hausding, Michael, Knorr, Maike, Pautz, Andrea, Reifenberg, Kurt, Schulz, Eberhard, Gori, Tommaso, Wenzel, Philip, Munzel, Thomas, and Daiber, and Andreas

Subjects
Diabetes -- Research -- Complications and side effects -- Care and treatment, Antioxidants -- Physiological aspects -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Health
Abstract

OBJECTIVE--Diabetes is associated with vascular oxidative stress, activation of NADPH oxidase, and uncoupling of nitric oxide (NO) synthase (endothelial NO synthase [eNOS]). Pentaerithrityl tetranitrate (PETN) is an organic nitrate with potent antioxidant properties via induction of heme oxygenase-1 (HO-1). We tested whether treatment with PETN improves vascular dysfunction in the setting of experimental diabetes. RESEARCH DESIGN AND METHODS--After induction of hyperglycemia by streptozotocin (STZ) injection (60 mg/kg i.v.), PETN (15 mg/kg/day p.o.) or isosorbide-5-mononitrate (ISMN; 75 mg/kg/day p.o.) was fed to Wistar rats for 7 weeks. Oxidative stress was assessed by optical methods and oxidative protein modifications, vascular function was determined by isometric tension recordings, protein expression was measured by Western blotting, RNA expression was assessed by quantitative RT-PCR, and HO-1 promoter activity in stable transfected cells was determined by luciferase assays. RESULTS--PETN, but not ISMN, improved endothelial dysfunction. NADPH oxidase and serum xanthine oxidase activities were significantly reduced by PETN but not by ISMN. Both organic nitrates had minor effects on the expression of NADPH oxidase subunits, eNOS and dihydrofolate reductase (Western blotting). PETN, but not ISMN, normalized the expression of GTP cyclohydrolase-1, extracellular superoxide dismutase, and S-glutathionylation of eNOS, thereby preventing eNOS uncoupling. The expression of the antioxidant enzyme, HO-1, was increased by STZ treatment and further upregulated by PETN, but not ISMN, via activation of the transcription factor NRF2. CONCLUSIONS--In contrast to ISMN, the organic nitrate, PETN, improves endothelial dysfunction in diabetes by preventing eNOS uncoupling and NADPH oxidase activation, thereby reducing oxidative stress. Thus, PETN therapy may be suited to treat patients with cardiovascular complications of diabetes. Diabetes 60:2608-2616, 2011, Diabetes is a major risk factor for the development of cardiovascular disease (1), and endothelial dysfunction is encountered early during the development of vascular complications in this setting (2). Animal [...]

Published
2011
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34. The importance and treatment of postprandial hyperglycemia

Author

Reid, Timothy S.

Subjects
Cardiovascular diseases -- Risk factors -- Prevention -- Research, Hyperglycemia -- Care and treatment -- Complications and side effects -- Research, Health
Abstract

LEARNING OBJECTIVES After reading this article, the primary care clinician should be better able to: 1. Explain the relative contribution of fasting plasma glucose and postprandial glucose (PPG) to cardiovascular [...]

Published
2010

35. Genetic deletion or pharmacological inhibition of dipeptidyl peptidase-4 improves cardiovascular outcomes after myocardial infarction in mice

Author

Sauve, Meghan, Ban, Kiwon, Momen, M. Abdul, Zhou, Yu-Qing, Henkelman, R. Mark, Husain, Mansoor, and Drucker, Daniel J.

Subjects
Gene mutations -- Health aspects -- Research, Heart attack -- Complications and side effects -- Research, Protease inhibitors -- Health aspects -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Type 2 diabetes -- Drug therapy -- Complications and side effects -- Genetic aspects -- Research, Health
Abstract

OBJECTIVE--Glucagon-like peptide-1 (7-36)amide (GLP-1) is cleaved by dipeptidyl peptidase-4 (DPP-4) to GLP-1 (9-36)amide. We examined whether chemical inhibition or genetic elimination of DPP-4 activity affects cardiovascular function in normoglycemic and diabetic mice after experimental myocardial infarction. RESEARCH DESIGN AND METHODS--Cardiac structure and function was assessed by hemodynamic monitoring and echocardiography in DPP-4 knockout ([Dpp4.sup.-/-]) mice versus wild-type ([Dpp4.sup.+/+]) littermate controls and after left anterior descending (LAD) coronary artery ligation-induced myocardial infarction (MI). Effects of sustained DPP-4 inhibition with sita-gliptin versus treatment with metformin were ascertained after experimental MI in a high-fat diet-streptozotocin model of murine diabetes. Functional recovery from ischemia-reperfusion (I/R) injury was measured in isolated hearts from [Dpp4.sup.-/-] versus [Dpp4.sup.+/+] littermates and from normoglycemic wild-type (WT) mice treated with sitagliptin or metformin. Cardioprotective signaling in the murine heart was examined by RT-PCR and Western blot analyses. RESULTS--[Dpp4.sup.-/-] mice exhibited normal indexes of cardiac structure and function. Survival post-MI was modestly improved in normoglycemic [Dpp4.sup.-/-] mice. Increased cardiac expression of phosphorylated AKT (pAKT), pGSK3β, and atrial natriuretic peptide (ANP) was detected in the nonischemic [Dpp4.sup.-/-] heart, and HO-1, ANP, and pGSK3β proteins were induced in nonischemic hearts from diabetic mice treated with sitagliptin or metformin. Sitagliptin and metformin treatment of wild-type diabetic mice reduced mortality after myocardial infarction. Sitagliptin improved functional recovery after I/R injury ex vivo in WT mice with similar protection from I/R injury also manifest in hearts from [Dpp4.sup.-/-] versus [Dpp4.sup.+/+] mice. CONCLUSIONS--Genetic disruption or chemical inhibition of DPP-4 does not impair cardiovascular function in the normoglycemic or diabetic mouse heart., Type 2 diabetes is associated with an increased risk of cardiovascular disease, hence there is considerable interest in strategies that reduce cardiovascular morbidity and mortality in diabetic subjects. Although aggressive [...]

Published
2010
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36. Researchers from Chinese Academy of Medical Sciences Detail New Studies and Findings in the Area of Atherosclerosis (Tea Consumption and the Risk of Atherosclerotic Cardiovascular Disease and All-cause Mortality: the China-par Project)

Subjects
Medical research -- Reports -- Health aspects, Medicine, Experimental -- Reports -- Health aspects, Mortality -- China, Tea -- Health aspects -- Reports -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Atherosclerosis -- Prevention -- Risk factors -- Research, Health
Abstract

2021 SEP 13 (NewsRx) -- By a News Reporter-Staff News Editor at Cardiovascular Week -- A new study on Cardiovascular Diseases and Conditions - Atherosclerosis is now available. According to [...]

Published
2021

37. New Findings Reported from Shahid Beheshti University of Medical Sciences Describe Advances in Cardiovascular Diseases and Conditions (Trajectories of cardiovascular disease risk and their association with the incidence of cardiovascular events ...)

Subjects
Medical research, Medicine, Experimental, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Health
Abstract

2021 AUG 6 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Researchers detail new data in cardiovascular diseases and conditions. According to news reporting [...]

Published
2021

38. Primordial cardiovascular prevention draws closer

Author

Jancin, Bruce

Subjects
Cardiovascular research -- Research, Genetic susceptibility -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Cholesterol, Low density lipoproteins, Trans fatty acids, Diseases, Novels, Health
Abstract

A powerful genetic predisposition to cardiovascular disease was overcome by low lifetime exposure to LDL cholesterol and systolic blood pressure in a naturalistic study conducted in nearly half a million [...]

Published
2020

39. Gender-affirming hormone therapy may not increase CVD risk for transgender adolescents

Subjects
Transgender people -- Research -- Health aspects, Teenagers -- Health aspects -- Research, Youth -- Health aspects -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Epidemiology -- Research -- Health aspects, Health, Psychology and mental health
Abstract

2021 MAY 31 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- DALLAS, - Transgender adolescents are more likely to have at least one cardiovascular [...]

Published
2021

40. New Findings on Diabetic Retinopathy Described by Investigators at Texas Technical University (The Association of Ideal Cardiovascular Health and Ocular Diseases Among Us Adults)

Subjects
Diabetic retinopathy -- Research -- Prevention -- Risk factors, Medical research, Medicine, Experimental, Technical institutes -- Research, Adults -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Health
Abstract

2021 APR 26 (NewsRx) -- By a News Reporter-Staff News Editor at Cardiovascular Week -- Researchers detail new data in Nutritional and Metabolic Diseases and Conditions - Diabetic Retinopathy. According [...]

Published
2021

41. University of British Columbia Researchers Yield New Study Findings on Type 1 Diabetes (Association between physical activity level and cardiovascular risk factors in adolescents living with type 1 diabetes mellitus: a cross-sectional study)

Subjects
Exercise -- Research -- Reports, Type 1 diabetes -- Research -- Prevention -- Risk factors, Teenagers -- Reports -- Research, Youth -- Reports -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Physical fitness -- Research -- Reports, Health, University of British Columbia -- Reports
Abstract

2021 MAR 29 (NewsRx) -- By a News Reporter-Staff News Editor at Cardiovascular Week -- Data detailed on type 1 diabetes have been presented. According to news originating from the [...]

Published
2021

42. Studies from Houston Methodist DeBakey Heart and Vascular Center Have Provided New Data on Cardiovascular Diseases and Conditions (Relation of Absence of Coronary Artery Calcium To Cardiovascular Disease Mortality Risk Among Individuals Meeting ...)

Subjects
Medical research -- Health aspects, Medicine, Experimental -- Health aspects, Cardiovascular agents -- Research, Cardiology -- Research -- Health aspects, Statins -- Research, Mortality -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Cardiac patients -- Research -- Health aspects, Health
Abstract

2021 FEB 5 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Current study results on Cardiovascular Diseases and Conditions have been published. According to [...]

Published
2021

43. The case for: hypoglycemia is of cardiovascular importance

Author

Lalic, Nebojsa M.

Subjects
Cardiovascular diseases -- Risk factors -- Prevention -- Research, Hypoglycemia -- Complications and side effects -- Drug therapy -- Research, Health
Abstract

Hypoglycemia, defined as a plasma glucose concentration The occurrence of hypoglycemia, both in experimental and human settings even without diabetes or related metabolic changes, provokes substantial increase in counterregulatory hormonal [...]

Published
2013
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44. Stand up for health: sitting too much can be bad for you, even if you get the recommended daily dose of exercise

Author

Gebel, Erika

Subjects
Exercise -- Health aspects -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Type 2 diabetes -- Complications and side effects -- Research, Food/cooking/nutrition, Health
Abstract

Not so long ago, the sight of a person standing at an office desk, instead of sitting, would have raised eyebrows. Now, there seems to be a legion of dedicated [...]

Published
2013

45. Early RA disease management may reduce risk of cardiovascular disease

Subjects
Cardiovascular diseases -- Risk factors -- Prevention -- Research, Rheumatoid arthritis -- Diagnosis -- Care and treatment -- Research, Health
Abstract

Inflammation early in the rheumatoid arthritis (RA) disease course is associated with 2 measures of arterial stiffness, increased pulse-wave velocity (PWV) and augmentation index (AIx), after 15 years. Early, active [...]

Published
2011

46. Research Findings from New York Medical College Update Understanding of Osteoporosis

Subjects
Osteoporosis -- Complications and side effects -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Health, Women's issues/gender studies
Abstract

A report, 'Osteoporosis, osteopenia, and atherosclerotic vascular disease,' is newly published data in Archives of Medical Science. 'Older women with low bone mineral density (BMD) have a higher prevalence of [...]

Published
2012

47. What You Need to Know About Cholesterol; Heart expert explains the difference between good and bad types

Subjects
Low density lipoproteins -- Health aspects -- Research, Cholesterol -- Health aspects -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Health
Abstract

MONDAY, March 27, 2017 (HealthDay News) -- Cholesterol plays a vital role in your health, so it's important to understand the different types of cholesterol and how to influence their [...]

Published
2017

48. New research explains how estrogen could help protect women from cardiovascular disease

Subjects
Immune response -- Health aspects -- Research, Menopause -- Health aspects -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Estrogen -- Health aspects -- Research, Health, Women's issues/gender studies
Abstract

The sex hormone oestrogen could help protect women from cardiovascular disease by keeping the body's immune system in check, new research from Queen Mary, University of London has revealed (see [...]

Published
2011

49. Cardiovascular disease: Statins shown to reduce blood pressure

Subjects
Blood pressure -- Measurement -- Health aspects -- Research, Statins -- Dosage and administration -- Research, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Health, Health care industry, Prevention, Measurement, Research, Risk factors, Dosage and administration, Health aspects
Abstract

A randomised, controlled trial has demonstrated a small but significant reduction in systolic and diastolic blood pressure with both a lipophilic and a hydrophilic statin. Nearly 1,000 men and women [...]

Published
2008

50. Stephen R Bloom

Subjects
Diabetes -- Complications and side effects -- Care and treatment -- Research -- Risk factors -- Prevention, Obesity -- Surgery, Cardiovascular diseases -- Risk factors -- Prevention -- Research, Biological sciences, Health
Abstract

Cancer has long been known to be associated with obesity, and one of the most surprising and welcome benefits of successful bariatric surgery has been the near halving of cancer [...]

Published
2012

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