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3 results on '"Frenay, H.M.E."'

1. Indigenous infection with Francisella tularensis holarctica in The Netherlands

Author

Maraha, B., Hajer, G.F., Sjödin, A., Forsman, M., Paauw, A., Roeselers, G., Verspui, E., Frenay, H.M.E., Notermans, D.W., Vries, M.C. de, and Reubsaet, F.A.G.

Subjects
Life, Health, CBRN - CBRN Protection, EELS - Earth, Environmental and Life Sciences, Infections
Abstract

We report here the first case of indigenous tularemia detected inTheNetherlands, a nonendemic country, since 1953.Whole genome DNAsequence analysis assigned the isolate BD11-00177 to the genomic group B.FTNF002-00,which previously has been exclusively reported from Spain, France, Italy, Switzerland, and Germany. The patient had not been abroad for years, which implies that this is an indigenous infection. The current case might predict an upcoming distribution of Francisella tularensis holarctica genomic group B.FTNF002-00 in Europe.

Published
2013

2. Draft genome sequence of Francisella tularensis subsp. holarctica BD11-00177

Author

Coolen, J.P.M., Sjödin, A., Maraha, B., Hajer, G.F., Forsman, M., Verspui, E., Frenay, H.M.E., Notermans, D.W., Vries, M.C. de, Reubsaet, F.A.G., Paauw, A., and Roeselers, G.

Subjects
Infostructures, Phylogeography, Life, Health, Biodefence, Zoonotic infection, CBRN - CBRN Protection, Information Society, Tularaemia, EELS - Earth, Environmental and Life Sciences, Netherlands
Abstract

Francisella tularensis is a facultative intracellular bacterium in the class Gammaproteobacteria. This strain is of interest because it is the etiologic agent of tularemia and a highly virulent category A biothreat agent. Here we describe the draft genome sequence and annotation of Francisella tularensis subsp. holarctica BD11-00177, isolated from the first case of indigenous tularemia detected in The Netherlands since 1953. Whole genome DNA sequence analysis assigned this isolate to the genomic group B.FTNF002-00, which previously has been exclusively reported from Spain, France, Italy, Switzerland and Germany. Automatic annotation of the 1,813,372 bp draft genome revealed 2,103 protein-coding and 46 RNA genes. © retained by original authors.

Published
2013

3. Draft genome sequence of Francisella tularensis subsp. holarctica BD11-00177

Author

Coolen, J.P.M., Sjödin, A., Maraha, B., Hajer, G.F., Forsman, M., Verspui, E., Frenay, H.M.E., Notermans, D.W., Vries, M.C. de, Reubsaet, F.A.G., Paauw, A., and Roeselers, G.

Subjects
Infostructures, Phylogeography, Life, Health, Biodefence, Zoonotic infection, CBRN - CBRN Protection, Information Society, Tularaemia, EELS - Earth, Environmental and Life Sciences, Netherlands
Abstract

Francisella tularensis is a facultative intracellular bacterium in the class Gammaproteobacteria. This strain is of interest because it is the etiologic agent of tularemia and a highly virulent category A biothreat agent. Here we describe the draft genome sequence and annotation of Francisella tularensis subsp. holarctica BD11-00177, isolated from the first case of indigenous tularemia detected in The Netherlands since 1953. Whole genome DNA sequence analysis assigned this isolate to the genomic group B.FTNF002-00, which previously has been exclusively reported from Spain, France, Italy, Switzerland and Germany. Automatic annotation of the 1,813,372 bp draft genome revealed 2,103 protein-coding and 46 RNA genes. © retained by original authors.

Published
2013

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