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Can damaged myelin, the tissue that insulates nerve fibers, be repaired in multiple sclerosis? Can altering the balance of gut bacteria help stop inflammation? Is it possible to reprogram microglia, [...]

2022 NOV 26 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- NRG Therapeutics, Ltd., an innovative neuroscience company targeting mitochondrial dysfunction, announced the [...]

2022 SEP 10 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Millions worldwide and an estimated 200,000 people in the United States have [...]

Billions of dollars are spent every year to support medical research, with a substantial percentage coming from charitable foundations. To justify these expenditures, some measure of the return on investment would be useful, particularly one aligned with the intended ultimate outcome of this scientific effort: the amelioration of disease. The current mode of reporting on the success of medical research is output based, with an emphasis on measurable productivity. This approach falls short in many respects and may be contributing to the well-described efficacy-effectiveness gap in clinical care. The author argues for an outcomes-based approach and describes the steps involved, using an adaptation of the logic model. A shift in focus to the outcomes of our work would provide our funders with clearer mission-central return-on-investment feedback, would make explicit the benefits of science to an increasingly skeptical public, and would serve as a compass to guide the scientific community in playing a more prominent role in reducing the efficacy-effectiveness gap. While acknowledging the enormous complexity involved with the implementation of this approach on a large scale, the author hopes that this essay will encourage some initial steps toward this aim and stimulate further discussion of this concept.

Summary points Almost 80% of Department of Health's research and development funding is allocated to NHS trusts, limiting the department's ability to set strategic direction Radical overhaul of strategy, delivery [...]

Just as there are sacred cows in the OR, there are myths about research. In our consultation with AORN members and other researchers, we have heard many of these myths. [...]

Current and future prospects for biomedical research are discussed by examining two critical questions, namely, how much money will be available and how it will be spent. Context is provided first by comparing how those same questions were answered 25 years ago with what has actually occurred between 1972 and the present. The questions are then addressed for a comparable period in the future. Projections are made for future funding for the National institutes of Health (NIH) and examples of new research directions are described. Ample grounds are provided for optimism about the future of biomedical research and NIH funding for it. (Lenfant C. Current and future NIH support of biomedical research. West J Med 1997 July; 167:15-18), I should tell you that the title was not of my choosing. It was Dr. Mason's. In his letter of invitation, he said, 'I believe the audience would be most [...]

FROM AN ODYSSEY THAT BEGAN WITH THE FIRST MANNED MISSIONS AND NOW CONTINUES WITH THE SUCCESSION OF SHUTTLE FLIGHTS, AMERICA'S EXPLORATION OF SPACE HAS HELPED LAUNCH TECHOLOGICAL AND CLINICAL BREAKTHROUGHS [...]

Europe has an unequalled tradition in scientific research. Most of the important discoveries in science before 1900 were made by Europeans in Europe. Britain, France, Germany, Italy, the Netherlands, and [...]

On a warm autumn morning last October, Beth Hagan laced up her sneakers and began walking to raise money and awareness for multiple sclerosis. Hagan, 46, of Havertown, Pa., who [...]

We don't know when the cure for MS will come, but we know we need a continuous stream of highly trained scientists and physicians to search for it and to [...]

The Peninsula Foundation, the charitable arm of the Peninsula College of Medicine and Dentistry, has secured funding of £15,000 from The Duchy Health Charity for research into Polycystic Ovary Syndrome [...]

The policy strategies are identified that are perceived by researchers active in Aboriginal and Torres Strait Islander health as effective in increasing the amount of high-quality intervention research undertaken in this field. Researchers active in Aboriginal health research have shown that improvements in funding mechanisms, priority setting and research systems are required to enhance the amount of high-quality intervention research being conducted in this field.

Research institutions leaving money on table Here's how to capture every cent An alarm went off when the research center at Yale University in New Haven, CT, was approached by [...]

The price is wrong: Poor pay = uninspired research Sponsors should change the way they pay Clinical research (CR) sponsors continue to impede the industry's overall productivity and efficiency by [...]

A study was conducted to evaluate the support provided by the National Health and Medical Research Council (NHMRC) for Indigenous health researchers from 1996 to 2006. Results indicated that though funding for Indigenous research through NHMRC has increased, it has failed to reach the target of at least 5% of agency allocation.

Washington roundup NIH grant oversight stuck in paper age for grant tracking A Medical Device Daily Staff Report The doubling of the budget of the National Institutes of Health between [...]

The Aetna Foundation has awarded a grant to the Institute for Safe Medication Practices (ISMP) of $38,500 to study medication reconciliation, a process that aims to improve patient safety and [...]

Qualitative research fits the nature of nurses' concerns as they have better understanding of the needs and experiences of patients. However, funding for such research is not available easily as compared to researchers seeking to find cures or more effective treatment for illnesses, therefore, nurses should make fewer applications, partner with experienced researchers where necessary and make sure that applications are articulated and proper.

Temporal trends in PubMed publications for Australian authors are determined as compared with changes in funding for health and medical research (HMR). It is ascertained that there is an association between increased funding for HMR and increased publications, as determined using PubMed, for the 10-year period 1006-2006.

Stem cell research guidelines offered by National Academies By CHRISTOPHER DELPORTE Medical Device Daily Washington Editor WASHINGTON - In an attempt to clarify some of the confusion and 'enhance the [...]

Salt Lake City -- A $100,000 grant to the University of Utah's John A. Moran Eye Center will support continued research into retinal cell transplantation in the treatment of retinitis [...]

Cleveland -- A $6 million federal grant will allow researchers at the Cleveland Clinic Cole Eye Institute to delve into the study of advanced imaging techniques used to diagnose and [...]

From Staff Reports New York--Four scientists will each receive $200,000 awards from Research to Prevent Blindness (RPB) over the next 4 years to support their research on eyes. Recipients are [...]

The Department of Health has cancelled funding for research and development commissioned through its regional offices for 2002-3, in order to divert savings of up to 10m £ ($15m) to [...]

Public confidence in the objectivity of research may be eroded Academia's relationship with private industry changed in the United States when Congress passed the Bayh-Dole Act in 1980.[1] This law [...]

EXCEPTIONAL artistic ability and a personal interest in diabetes produced 12 winning entries in this year's American Diabetes Association (ADA) Holiday Art Search. The fifth annual ADA Holiday Art Search, [...]

President George Bush took the unusual move of using a nationally televised address last week to announce that he would allow government supported research on existing embryonic cell lines only, [...]

Johns Hopkins University School of Medicine (Baltimore, Maryland) and the University of Pennsylvania have received research grants of about $8 million over a five-year period from the National Center for [...]

The United Nations' secretary general, Kofi Annan, has called for spending on AIDS to be increased 10-fold in developing countries. He wants a 'war chest' of $7bn-10bn (5bn £-7bn) to [...]