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Your search keyword '"Berardino, S."' showing total 2 results
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2 results on '"Berardino, S."'

1. [The incremental prognostic value of the scintigraphic indices of myocardial hypoperfusion in patients with a maximal stress test].

Author

Petretta M, Cuocolo A, Bianchi V, Nicolai E, Berardino S, Arrichiello P, Themistoklakis S, Tesorio M, and Bonaduce D

Subjects
Adult, Aged, Chi-Square Distribution, Disease Progression, Exercise Test methods, Exercise Test statistics & numerical data, Female, Follow-Up Studies, Heart physiopathology, Humans, Male, Middle Aged, Myocardial Infarction epidemiology, Myocardial Ischemia diagnostic imaging, Myocardial Ischemia physiopathology, Prognosis, Radionuclide Imaging, Thallium Radioisotopes, Coronary Circulation, Heart diagnostic imaging
Abstract

The additional prognostic value of thallium imaging in patients who are capable of performing a maximal, symptom-limited electrocardiographic stress test is still uncertain. Thus, we evaluated the incremental prognostic value of exercise thallium-201 indexes of myocardial hypoperfusion in 296 patients with suspected or known coronary artery disease who performed a maximal ECG stress test. At 2 year follow-up 20 hard events (16 cardiac deaths and 4 non fatal myocardial infarctions) and 44 soft events (myocardial revascularization procedures) occurred. Considering total events, thallium imaging provided significant additional prognostic information to clinical and exercise stress test data in all patients (p < 0.001) and in patients with previous myocardial infarction (p < 0.001); in patients without previous infarction, whichever the end-point considered, thallium imaging did not add incremental prognostic value. When only hard events were considered, thallium variables added further information only in patients with previous myocardial infarction (p < 0.05). The results of this study demonstrate that scintigraphic indexes of myocardial hypoperfusion obtained by qualitative planar thallium imaging give incremental prognostic information in patients with previous myocardial infarction but not in the subset of patients without previous infarction.

Published
1994

2. Incremental prognostic value of thallium reinjection after stress-redistribution imaging in patients with previous myocardial infarction and left ventricular dysfunction

Author

Mario Petretta, Cuocolo, A., Bonaduce, D., Nicolai, E., Cardei, S., Berardino, S., Ianniciello, A., Apicella, C., Bianchi, V., Salvatore, M., Petretta, Mario, A., Cuocolo, Bonaduce, Domenico, Nicolai, E, Cardei, S, Berardino, S, Ianniciello, A, Apicella, C, Bianchi, V, Salvatore, M., Cuocolo, A, Salvatore, Marco, and Cuocolo, Alberto

Subjects
Male, Tomography, Emission-Computed, Single-Photon, Analysis of Variance, Likelihood Functions, Risk stratification/prognosis, Myocardial Infarction, Heart, Middle Aged, Prognosis, Coronary artery disease, Survival Analysis, Thallium Radioisotopes, Ventricular Dysfunction, Left, Exercise Test, Humans, Female, Radionuclide Imaging, Proportional Hazards Models
Abstract

This study evaluated the incremental prognostic value of 201TI reinjection imaging over clinical, exercise and thallium stress-redistribution data in patients with previous myocardial infarction and left ventricular dysfunction. METHODS: Thallium-201 reinjection after stress-redistribution SPECT was performed in 104 consecutive patients with a first Q-wave myocardial infarction (> 8 wk) and left ventricular ejection fraction < or = 40%. Follow-up data (mean 22 mo) were available for 98 patients; 16 patients underwent early revascularization procedures within 3 mo after exercise testing and were not considered for the analysis. RESULTS: During follow-up there were 13 hard events (cardiac death and myocardial infarction) and 11 soft events (coronary revascularization procedures > 3 mo after thallium imaging). With multivariate Cox regression analysis, the sum of defects at stress-redistribution imaging that were reversible or moderate irreversible after reinjection was a powerful predictor of subsequent events. The addition of thallium reinjection imaging data significantly improved the prognostic power of clinical, exercise and stress-redistribution data for the occurrence of hard events (p < 0.01). CONCLUSION: In patients with previous myocardial infarction and left ventricular dysfunction, thallium reinjection imaging provides incremental prognostic information over those obtained from conventional stress-redistribution imaging.

Published
1997

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