1. Histopathology of congestive nephropathy: a case description and literature review.
- Author
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Husain-Syed F, Rangaswami J, Núñez J, Skrzypek S, Jux C, Gröne HJ, and Birk HW
- Subjects
- Humans, Male, Middle Aged, Biopsy, Heart Transplantation, Kidney pathology, Acute Kidney Injury etiology, Acute Kidney Injury diagnosis, Heart Failure etiology, Heart Failure diagnosis
- Abstract
Congestive nephropathy is an underappreciated manifestation of cardiorenal syndrome and is characterized by a potentially reversible kidney dysfunction caused by a reduced renal venous outflow secondary to right-sided heart failure or intra-abdominal hypertension. To date, the histological diagnostic criteria for congestive nephropathy have not been defined. We herein report a case of acute renal dysfunction following cardiac allograft failure and present a review of the relevant literature to elucidate the current understanding of the disease. Our case demonstrated that congestion-driven nephropathy may be histopathologically characterized by markedly dilated veins and peritubular capillaries, focally accentuated low-grade acute tubular damage, small areas of interstitial fibrosis, and tubular atrophy on a background of normal glomeruli and predominantly normal tubular cell differentiation., (© 2024 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.)
- Published
- 2024
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