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Your search keyword '"Orthotopic Cardiac Transplantation"' showing total 6 results
Start Over Descriptor "Orthotopic Cardiac Transplantation" Topic heart transplantation
6 results on '"Orthotopic Cardiac Transplantation"'

1. FACTORS OF LIFE QUALITY IMPROVEMENT AFTER HEART TRANSPLANTATION: PREDICTIVE SIGNIFICANCE OF CARDIOPULMONARY EXERCISE TEST

Author

O. V. Kamenskaya, I. Yu. Loginova, D. V. Doronin, A. M. Chernyavsky, and A. M. Karaskov

Subjects
Heart transplantation, medicine.medical_specialty, business.industry, medicine.medical_treatment, Life quality, Physical health, Predictive value, Transplantation, Psychological health, Waiting list, RC666-701, Physical therapy, Medicine, Diseases of the circulatory (Cardiovascular) system, Exertion, life quality, Cardiology and Cardiovascular Medicine, business, cardiopulmonary exercise test, orthotopic cardiac transplantation
Abstract

Aim . Evaluation of prognostic significance of the parameters of cardiopulmonary exercise test in life quality improvement for the post-cardiac transplantation patients. Material and methods. Into the study, 40 patients included, with severe chronic heart failure (CHF), included in the waiting list for cardiac transplantation. Before and after orthotopic heart transplantation (OHT), clinical status was evaluated, cardiopulmonary exercise testing parameters (CET) and life quality by SF-36. Results . After OHT the significant life quality improvement noted, by the scale “Physical health” from 36 (32-45) points before surgery to 52 (49-55) points (p

Published
2017

2. Optimal Cardiac Pacing After Heart Transplantation.

Author

Melton, Iain C., Gilligan, David M., Wood, Mark A., and Ellenbogen, Kenneth A.

Subjects
CARDIAC pacing, HEART transplantation, CARDIAC pacemakers, CARDIAC surgery, BRADYCARDIA
Abstract

The transplanted heart is characterized physiologically by autonomic denervation, chronotropic incompetence, intermittent episodes of allograft rejection, and frequently by diastolic dysfunction. Sinus node dysfunction resulting in bradycardia is common in the early postoperative period following standard orthotopic cardiac transplantation. Bradycardia tends to remit spontaneously but there are no factors that accurately identify patients who will need long-term pacing. Patients in whom bradycardia persists beyond the second postoperative week despite treatment with theophylline require permanent pacemaker implantation. It has been observed that chronotropic incompetence and diastolic dysfunction are important determinants of exercise capacity following heart transplantation. Pacing that restores chronotropic competence improves exercise capacity, confirming the importance of impaired heart rate response. As in other settings, pacing that preserves atrioventricular (AV) synchrony results in increased cardiac output. For these reasons when pacing is necessary we recommend the DDDR mode (AAIR if intact AV nodal conduction is present) so that the 30%-50% of patients who remain pacemaker-dependent long-term obtain maximal benefit from their transplant. [ABSTRACT FROM AUTHOR]

Published
1999
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3. Pretransplant pulmonary hypertension and long-term allograft right ventricular function

Author

Roger Hullin, Eric Wigger, Thierry Carrel, Paul Mohacsi, Christoforos Stoupis, Hildegard Tanner, Martin Feller, and Andreas Wahl

Subjects
Adult, Pulmonary and Respiratory Medicine, Cardiac Catheterization, medicine.medical_specialty, Hypertension, Pulmonary, Ventricular Dysfunction, Right, medicine.medical_treatment, Hemodynamics, Internal medicine, Humans, Medicine, Systole, Aged, Immunosuppression Therapy, Postoperative Care, Heart transplantation, Lung, business.industry, Graft Survival, Respiratory disease, General Medicine, Middle Aged, Prognosis, medicine.disease, Magnetic Resonance Imaging, Pulmonary hypertension, Transplantation, surgical procedures, operative, medicine.anatomical_structure, Cardiac Transplantation, Pretransplant Pulmonary Hypertension, Right Ventricular Function, Cardiac Magnetic Resonance Imaging, Orthotopic Cardiac Transplantation, Heart-Transplantation, Vascular-Resistance, Follow-Up, Artery Pressure, Mortality, Predicts, Risk, Reversibility, Candidates, Circulatory system, Ventricular Function, Right, Cardiology, Heart Transplantation, Surgery, Collagen, Epidemiologic Methods, Cardiology and Cardiovascular Medicine, business
Abstract

Background: Graft right ventricular (RV) function is compromised directly posttransplant, especially in heart transplantation (HTx) recipients with pretransplant pulmonary hypertension (PH). Graft RV size and systolic function, and the effect of the recipient's pulmonary haemodynamics on the graft extracellular matrix are not well characterised in the patients long-term after HTx. Aim: Comparison of RV size and systolic function in HTx recipients' long-term posttransplant stratified by the presence of pretransplant PH. Methods: HTx survivors >/=2 years posttransplant were divided into group I without pretransplant PH (pulmonary vascular resistance, PVR /=2.5Wood units, n=16). RV size and systolic function were measured using cardiac magnetic resonance imaging (CMR). The collagen content was assessed in septal endomyocardial biopsies obtained at HTx and at study inclusion. Results: Mean posttransplant follow-up was 5.2+/-2.9 years (group I) and 4.9+/-2.2 years (group II) (p=0.70). PVR was 1.5+/-0.6 vs 4.1+/-1.7Wood units pretransplant (p/=0.07). Collagen content at transplantation and at follow-up were not different (p always >/=0.60). Conclusion: Posttransplant normalisation of pretransplant PH is associated with normal graft RV function long-term after HTx.

Published
2017
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4. Evidence for differential sympathetic and parasympathetic reinnervation after heart transplantation in humans

Subjects
STRESS, ORTHOTOPIC CARDIAC TRANSPLANTATION, heart rate variability, EXERCISE, autonomic testing, RATE-VARIABILITY, heart transplantation, reinnervation, INCREASE, RECIPIENTS, CORONARY-ARTERY DISEASE, SPECTRAL-ANALYSIS, human, HEALTHY, RESPONSES
Abstract

During heart transplantation (HTX) all neural connections are severed, Ln humans, signs of autonomic reinnervation have been found, in this study non-invasive tests were used to compare signs of sympathetic and parasympathetic reinnervation. Non-invasive autonomic function tests and heart rate variability parameters (HRV; 24 h electrocardiographic registration) were used to investigate signs of reinnervation, 16 HTX patients (14 males) were compared with age-and sex-matched controls, Parasympathetic heart rate changes in HTX compared to controls were attenuated during the diving test, deep breathing, the Valsalva maneuver and standing up but not during carotid sinus massage, Sympathetic heart rate increases were lower during the cold presser test and mental stress, The blood pressure responses were comparable to the control group, but not during active standing and tilting. This finding suggests an obligatory 'blood pressure' role for the innervated heart in these two tests, All HRV parameters were lower in HTX. One or more normal parasympathetic responses were found in 13 out of 16 patients versus 4 out of 16 with normal sympathetic responses (p

Published
1997

5. Orthotopic cardiac transplantation for the treatment of progressive heart failure caused by idiopathic giant cell myocarditis

Author

Ito, Hiroki and Hong, Robert A.

Subjects
*HEART failure, *HEART transplantation, *MYOCARDITIS, *IMMUNOSUPPRESSION
Abstract

Abstract: We describe a patient with idiopathic giant cell myocarditis who underwent orthotopic cardiac transplantation. On triple immunosuppressive therapy including prednisone, cyclosporine and mycophenolate, the patient has not had recurrence of idiopathic giant cell myocarditis in the transplanted heart in 48 months of follow-up. [Copyright &y& Elsevier]

Published
2007
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6. Evidence for differential sympathetic and parasympathetic reinnervation after heart transplantation in humans

Author

M.P. van den Berg, R. M. H. J. Brouwer, Jaap Haaksma, R. A. Tio, Anna K.L. Reyners, Hjgm Crijns, Andries J. Smit, D. J. Van Veldhuisen, Guided Treatment in Optimal Selected Cancer Patients (GUTS), Targeted Gynaecologic Oncology (TARGON), Cardiovascular Centre (CVC), Groningen Kidney Center (GKC), and Vascular Ageing Programme (VAP)

Subjects
Adult, Male, Sympathetic nervous system, Sympathetic Nervous System, STRESS, Physiology, medicine.medical_treatment, EXERCISE, Baroreflex, heart transplantation, INCREASE, Heart Rate, Parasympathetic Nervous System, SPECTRAL-ANALYSIS, Heart rate, Humans, Medicine, Heart rate variability, Postoperative Period, human, HEALTHY, Heart transplantation, business.industry, General Neuroscience, ORTHOTOPIC CARDIAC TRANSPLANTATION, Cold pressor test, heart rate variability, Heart, autonomic testing, RATE-VARIABILITY, Middle Aged, reinnervation, Nerve Regeneration, Autonomic nervous system, RECIPIENTS, medicine.anatomical_structure, CORONARY-ARTERY DISEASE, Anesthesia, Female, Neurology (clinical), business, Reinnervation, RESPONSES
Abstract

During heart transplantation (HTX) all neural connections are severed, Ln humans, signs of autonomic reinnervation have been found, in this study non-invasive tests were used to compare signs of sympathetic and parasympathetic reinnervation. Non-invasive autonomic function tests and heart rate variability parameters (HRV; 24 h electrocardiographic registration) were used to investigate signs of reinnervation, 16 HTX patients (14 males) were compared with age-and sex-matched controls, Parasympathetic heart rate changes in HTX compared to controls were attenuated during the diving test, deep breathing, the Valsalva maneuver and standing up but not during carotid sinus massage, Sympathetic heart rate increases were lower during the cold presser test and mental stress, The blood pressure responses were comparable to the control group, but not during active standing and tilting. This finding suggests an obligatory 'blood pressure' role for the innervated heart in these two tests, All HRV parameters were lower in HTX. One or more normal parasympathetic responses were found in 13 out of 16 patients versus 4 out of 16 with normal sympathetic responses (p

Published
1997

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