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7 results on '"neutropenic diet"'

1. Microbial Evaluation of Neutropenic Diet in Bone Marrow Transplant Department in Iran

Author

Mahsa Tousi, Abdolreza Norouzy, Mohammad Vaezi, Ali Ghasemi, maryam khosravi, and Ardeshir Ghavamzade

Subjects
Bacterial contamination, Food-borne, Hematopoietic stem cell transplantation, Neutropenic diet, Medicine (General), R5-920
Abstract

Background: The use of a neutropenic diet after hematopoietic stem cell transplantation (HSCT) was instituted more than 30 years ago. This diet was targeted toward preventing from infection with organisms colonizing the gastrointestinal tract and the food-borne pathogens, which are the most important cause of illness and death in developing countries. Regarding this, the present study aimed to evaluate neutropenic diet in patients undergoing bone marrow transplantation in a selected hospital. This study also sought to investigate the role of hospital foods in the transmission of clinically important bacteria to the hospitalized patients. Materials and Methods: This cross-sectional study was conducted on the specimens of the foods served in the Bone Marrow Transplant Department of Shariati Hospital, Tehran, Iran. The samples were evaluated in terms of bacterial contamination using the standard method ‎of American Public Health Association and Food and Drug Administration (FDA). Results: According to total bacteria and coliform counts, No contamination was detected in any of the tested specimens. Conclusion: As the findings indicated, the neutropenic diet, was found to be fully in line with the standards of the Ministry of Health and FDA both in terms of guidelines and food analysis.

Published
2018
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2. Mediterranean Diet: Outcomes from an education session among patients with cancer and nursing staff.

Author

Otten, Karine R., Staffileno, Beth A., Mozer, Marisa, and Maidlow, Cate

Subjects
*ONCOLOGY nursing, *CANCER patients, *HEMATOPOIETIC stem cell transplantation, *NURSES, *NURSES' attitudes, *PATIENT education, *QUESTIONNAIRES, *RESEARCH funding, *STATISTICAL sampling, *SCALE analysis (Psychology), *TEACHING aids, *PRE-tests & post-tests, *HEALTH literacy, *PATIENTS' attitudes, *DESCRIPTIVE statistics, *MEDITERRANEAN diet, *HEMATOLOGIC malignancies
Abstract

BACKGROUND: Strong evidence supports the benefits of the Mediterranean diet, but little is reported among patients and nurses regarding knowledge about the diet and its health benefits. OBJECTIVES: A pre-/post-test practice initiative was implemented to identify level of knowledge about the Mediterranean diet in patients with cancer and nursing staff and to provide education about the diet's health benefits. METHODS: A 17-item survey was developed to assess knowledge and willingness to try or recommend the Mediterranean diet, current practices, and general nutrition knowledge. A 10-minute education session was provided to patients and nursing staff. Descriptive statistics were used. FINDINGS: The majority of patients reported eating from one to four servings of fruits and vegetables daily. For patients and nursing staff, post--education session scores demonstrated increased knowledge, willingness to try the diet, and perceived effectiveness of the diet. [ABSTRACT FROM AUTHOR]

Published
2020
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3. Comparing a Neutropenic Diet to a Food Safety-Based Diet in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation.

Author

Taggart, Cynthia, Neumann, Nicole, Alonso, Priscila Badia, Lane, Adam, Pate, Abigail, Stegman, Audrey, Stendahl, Ava, Davies, Stella M., Dandoy, Christopher E., and Grimley, Michael

Subjects
*BUSULFAN, *HEMATOPOIETIC stem cell transplantation, *HEMATOPOIETIC stem cells, *STEM cell transplantation, *DIET, *GRAFT versus host disease
Abstract

• Neutropenic diet; low bacterial diet; hematopoietic stem cell transplant; bloodstream infections; nutrition; supportive care Neutropenic diets were adopted as a way to decrease the infection risks in immunocompromised individuals, but these diets result in significant restrictions in the variety and types of foods an individual may consume. We used a controlled before-and-after study design in consecutive pediatric and young adult patients who underwent hematopoietic stem cell transplant at our center between January 1, 2014, and December 31, 2014. From January through June, all patients were placed on a traditional neutropenic diet; on July 1, we liberalized the bone marrow transplant (BMT) diet to a modified BMT diet. We compared the incidence of bloodstream infections in the first 100 days post-transplant, incidence of norovirus in the first 100 days, total parenteral nutrition days through day 100, incidence of grade 3 to 4 graft-versus-host disease at day 100, gastrointestinal graft-versus-host disease (any stage), and 100-day overall survival. In addition, we administered an investigator-created survey to evaluate food cravings, nausea, diet limitations, and subjective quality of life. In total, 102 patients underwent hematopoietic stem cell transplant during the study period. Forty-nine (48%) received the neutropenic diet and 53 (52%) the BMT diet. Other than more males receiving the neutropenic diet (67% versus 47%, P = 0.05), there were no statistical demographic and outcome differences between the 2 groups. Additionally, 46 subjects (45%) completed the investigator-created questionnaire. There was no difference in the perceived food cravings, nausea, diet limitations, and subjective quality of life between the 2 cohorts. These data demonstrate noninferiority of the modified BMT diet over the traditional neutropenic diet. We believe the food safety-based diet offers a greater variety of food, which may assist in the transition to a normal diet. [ABSTRACT FROM AUTHOR]

Published
2019
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4. Features of nutritional support during stem cell transplantation

Author

S. A. Volchenkov, L. V. Filatova, E. V. Cherkasova, A. K. Koviazin, S. V. Lyubimov, I. S. Zyuzgin, and T. Yu. Semiglazova

Subjects
Vitamin, Nitrogen balance, medicine.medical_specialty, medicine.medical_treatment, nutritional support, Hematopoietic stem cell transplantation, allogeneic and autologous hematopoietic stem cell transplantation, immunonutrients, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, neutropenic diet, Vitamin D and neurology, Medicine, Chemotherapy, business.industry, Incidence (epidemiology), General Medicine, Protein requirement, medicine.disease, Malnutrition, chemistry, nutritional insufficiency, 030220 oncology & carcinogenesis, business, 030215 immunology
Abstract

This article presented a review of the literature on the features of nutritional support for oncohematological patients who have undergone allogeneic (alloHSCT)/autologous hematopoietic stem cell transplantation (autoHSCT). Bone marrow transplantation associated with a high risk of developing nutritional deficiencies. Nutritional support (NP) is indicated for patients undergoing alloHSCT and autoHSCT in order to reduce the incidence of infectious complications and reduce the risk of developing severe forms of acute and chronic GVHD. Currently, there are recommendations for conducting NP in alloHSCT, while there are no recommendations for patients with autoHSCT. An important task in planning NP is the calculation of the daily energy requirement. Bone marrow transplantation accompanied by a prolonged negative nitrogen balance. The protein requirement for alloHSCT is significantly higher than for patients with chemotherapy alone – 1.5–2 g/kg per day. An effective method of controlling the needs of hematological patients during the analysis of HSCT and alloHSCT is the calculation of the nitrogen balance and the daily protein norm. In this article was analyzed the role of macronutrients and immunonutrients in the recovery of patients during alloHSCT. It has been shown that low levels of vitamin D and vitamin A increase the risk of development and the severity of the transplant versus host reaction. The addition of omega-3 fatty acids helps maintain an optimal proportion of calorie intake from lipids, as well as maintain the necessary level of triglycerides in the blood. The article presents data on reducing the risk of developing acute GVHD with systemic addition of omega-3 fatty acids. For a final assessment of the effect of the neutropenic diet on the development of infectious complications in oncohematological patients, randomized prospective multicenter studies with the development of a unified approach in choosing a diet for HSCT are needed.

Published
2020

5. Supportive Care During Pediatric Hematopoietic Stem Cell Transplantation : Prevention of Infections. A Report From Workshops on Supportive Care of the Paediatric Diseases Working Party (PDWP) of the European Society for Blood and Marrow Transplantation (EBMT)

Author

Marianne Ifversen, Roland Meisel, Petr Sedlacek, Krzysztof Kalwak, Luisa Sisinni, Daphna Hutt, Thomas Lehrnbecher, Adriana Balduzzi, Tamara Diesch, Andrea Jarisch, Tayfun Güngör, Jerry Stein, Isaac Yaniv, Halvard Bonig, Michaela Kuhlen, Marc Ansari, Tiago Nava, Jean-Hugues Dalle, Cristina Diaz-de-Heredia, Eugenia Trigoso, Ulrike Falkenberg, Mihaela Hartmann, Marco Deiana, Marta Canesi, Chiara Broggi, Alice Bertaina, Brenda Gibson, Gergely Krivan, Kim Vettenranta, Toni Matic, Jochen Buechner, Anita Lawitschka, Christina Peters, Akif Yesilipek, Koray Yalçin, Giovanna Lucchini, Shahrzad Bakhtiar, Dominik Turkiewicz, Riitta Niinimäki, Jacek Wachowiak, Simone Cesaro, Arnaud Dalissier, Selim Corbacioglu, Andre Manfred Willasch, Peter Bader, Children's Hospital, Lastentautien yksikkö, HUS Children and Adolescents, Ifversen, M, Meisel, R, Sedlacek, P, Kalwak, K, Sisinni, L, Hutt, D, Lehrnbecher, T, Balduzzi, A, Diesch, T, Jarisch, A, Gungor, T, Stein, J, Yaniv, I, Bonig, H, Kuhlen, M, Ansari, M, Nava, T, Dalle, J, Diaz-de-Heredia, C, Trigoso, E, Falkenberg, U, Hartmann, M, Deiana, M, Canesi, M, Broggi, C, Bertaina, A, Gibson, B, Krivan, G, Vettenranta, K, Matic, T, Buechner, J, Lawitschka, A, Peters, C, Yesilipek, A, Yalcin, K, Lucchini, G, Bakhtiar, S, Turkiewicz, D, Niinimaki, R, Wachowiak, J, Cesaro, S, Dalissier, A, Corbacioglu, S, Willasch, A, Bader, P, Institut Català de la Salut, [Ifversen M] Department of Paediatrics and Adolescent Medicine, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark. [Meisel R] Division of Pediatric Stem Cell Therapy, Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich-Heine-University, Duesseldorf, Germany. [Sedlacek P] Department of Pediatric Hematology and Oncology, Hospital Motol, Charles University, Prague, Czechia. [Kalwak K] Department of Pediatric Hematology, Oncology and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland. [Sisinni L] Pediatric Hematology, Oncology and Hematopoietic Stem Cell Transplantation Unit, Hospital Santa Creu i Sant Pau, Barcelona, Spain. [Hutt D] Division of Pediatric Hematology, Oncology and Bone Marrow Transplantation, The Edmond and Lily Safra Children's Hospital, Tel Aviv, Israel. [Diaz-de-Heredia C] Servei d’Oncologia i Hematologia Pediàtriques, Vall d'Hebron Hospital Universitari, Barcelona, Spain, and Vall d'Hebron Barcelona Hospital Campus

Subjects
medicine.medical_treatment, allogeneic hematological stem cell transplantation, CHILDREN, Hematopoietic stem cell transplantation, Otros calificadores::Otros calificadores::/efectos adversos [Otros calificadores], GUIDELINES, Pediatrics, PROPHYLAXIS, 0302 clinical medicine, 3123 Gynaecology and paediatrics, Antibiotic prophylactic therapy, Young adult, Children, antibiotic prophylactic therapy, Original Research, COMPLICATIONS, Hematology, ddc:618, Therapeutics::Biological Therapy::Immunomodulation::Immunotherapy::Immunosuppression::Transplantation Conditioning [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT], terapéutica::terapia biológica::inmunomodulación::inmunoterapia::inmunosupresión::acondicionamiento para el trasplante [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS], Vaccination, Hematopoietic stem cell, allogeneic hematological stem cell transplantation, antibiotic prophylactic therapy, children, infection precaution, vaccination, CHEMOTHERAPY, CANCER, 3. Good health, Leukemia, medicine.anatomical_structure, surgical procedures, operative, 030220 oncology & carcinogenesis, Cohort, terapéutica::terapia biológica::tratamientos basados en células y tejidos::trasplante de células::trasplante de células madre::trasplante de células madre hematopoyéticas [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS], medicine.medical_specialty, Cirurgia - Complicacions, Isolation (health care), Pathological Conditions, Signs and Symptoms::Pathologic Processes::Postoperative Complications [DISEASES], RJ1-570, 03 medical and health sciences, Internal medicine, medicine, Other subheadings::Other subheadings::/adverse effects [Other subheadings], PARTICULATE AIR FILTRATION, infection precaution, ddc:610, NEUTROPENIC DIET, Intensive care medicine, Donor selection, business.industry, Cèl·lules mare hematopoètiques - Trasplantació, medicine.disease, vaccination, afecciones patológicas, signos y síntomas::procesos patológicos::complicaciones posoperatorias [ENFERMEDADES], RECIPIENTS, Infection precaution, Pediatrics, Perinatology and Child Health, Sang - Malalties, Therapeutics::Biological Therapy::Cell- and Tissue-Based Therapy::Cell Transplantation::Stem Cell Transplantation::Hematopoietic Stem Cell Transplantation [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT], business, Allogeneic hematological stem cell transplantation, LEUKEMIA, 030215 immunology
Abstract

Terapia profiláctica antibiótica; Niños; Vacunación Teràpia profilàctica antibiòtica; Nens; Vacunació Antibiotic prophylactic therapy; Children; Vaccination Specific protocols define eligibility, conditioning, donor selection, graft composition and prophylaxis of graft vs. host disease for children and young adults undergoing hematopoietic stem cell transplant (HSCT). However, international protocols rarely, if ever, detail supportive care, including pharmaceutical infection prophylaxis, physical protection with face masks and cohort isolation or food restrictions. Supportive care suffers from a lack of scientific evidence and implementation of practices in the transplant centers brings extensive restrictions to the child's and family's daily life after HSCT. Therefore, the Board of the Pediatric Diseases Working Party (PDWP) of the European Society for Blood and Marrow Transplantation (EBMT) held a series of dedicated workshops since 2017 with the aim of initiating the production of a set of minimal recommendations. The present paper describes the consensus reached within the field of infection prophylaxis.

Published
2021

6. Adherence to guidelines on nutrition support during intensive treatment of acute myeloid leukemia patients: A nationwide comparison

Author

Debbie van der Lee, Willy K Visser, Stephanie Custers, Lidwine W. Tick, Suzanne Kranenburg, Ingeborg M. Dekker, Doris Kalter, Rianne van Lieshout, Maaike Somer, Harry C. Schouten, Claudia J. van Tilborg, Madieke D Douma, Sandra Beijer, Patricia Rhoon-Bruijnzeel, Ien Schlösser, Daphne de Laat, MUMC+: TPZ Dietetiek (9), RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Interne Geneeskunde, Internal Medicine, Internal medicine, and CCA - Cancer Treatment and quality of life

Subjects
0301 basic medicine, medicine.medical_specialty, Dieticians, Nutrition support practices, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Nutritional Status, 030209 endocrinology & metabolism, Hematopoietic stem cell transplantation, Clinical nutrition, Computer-assisted web interviewing, CANCER-PATIENTS, Intensive chemotherapy, Enteral administration, THERAPY, PARAMETERS, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, NEUTROPENIC DIET, Intensive care medicine, 030109 nutrition & dietetics, Nutrition and Dietetics, Acute myeloid leukemia, Nutritional Support, business.industry, ESPEN GUIDELINES, MORTALITY, PARENTERAL-NUTRITION, Adult Acute Myeloid Leukemia, STEM-CELL TRANSPLANTATION, Guideline, Parenteral nutrition, Leukemia, Myeloid, Acute, Nutrition Assessment, BODY-WEIGHT, RESTING ENERGY-EXPENDITURE, business, Enteral nutrition
Abstract

Background & aims: The level of adherence to the updated guidelines of The European Societies for Clinical Nutrition and Metabolism (ESPEN) and for Blood and Marrow Transplantation (EBMT) on nutrition in intensively treated adult acute myeloid leukemia (AML) patients in clinical practice is unknown. The aim of this nationwide survey was to investigate ESPEN/EBMT nutritional guideline adherence during intensive AML treatment, variation in nutrition support practices among hospitals and whether these practices changed after guideline publication.Methods: All 22 Dutch hospitals providing (aftercare following) high-dose chemotherapy and/or hematopoietic stem cell transplantation for adult AML patients were surveyed on nutrition support practices during these intensive AML treatments. We used an online questionnaire in 2015 and semi structured telephone interviews in 2018-2019. Both surveys were completed by registered dieticians and addressed the use of enteral (EN) and parenteral (PN) nutrition. The ESPEN/EBMT nutritional guideline adherence was investigated through the telephone interviews.Results: High-level ESPEN/EBMT guideline adherence and/or uniformity among hospitals regarding nutrition support practices during intensive AML treatment were observed for nutritional screening,-aims, safe food handling and exercise training. Adherence to ESPEN/EBMT recommendations that were not implemented into national guidelines, including nutritional assessment and use of medical nutrition, was poor. All hospitals assessed nutritional intake,-impact symptoms and body weight, but muscle mass, physical performance and degree of systemic inflammation were rarely and variably monitored. Although the number of hospitals using EN as first-choice nutritional intervention increased from 3 hospitals in 2015 to 8 in 2019, PN remained the preferred method of nutrition support. Furthermore, the timing of medical nutrition varied.Conclusions: Although the use of EN increased after publication of the updated ESPEN/EBMT nutritional guidelines, adherence to these standards was limited and there was heterogeneity in nutrition support practices during intensive AML treatment among hospitals. Incorporating international nutritional standards into national guidelines by nutrition expert groups immediately upon publication may improve adherence. (c) 2020 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.

Published
2020
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7. Medical Nutritional Therapy in Hematopoietic Stem Cell Transplantation (HSCT).

Author

AKBULUT, Gamze

Subjects
*HEMATOPOIETIC stem cell transplantation, *APLASTIC anemia, *LEUKEMIA, *DISEASE complications, *ARTIFICIAL feeding, *ENTERAL feeding
Abstract

Hematopoietic Stem Cell Transplantation (HSCT) is a method used for the treatment of patients with severe aplastic anemia, leukaemia and some other malignancies. As it causes many adverse sequelaes (anorexia, nausea, vomiting, diarrhea, and mucositis), adequate oral diet is usually unachievable and artificial nutrition support is required. In order to reduce the risk of infections, the protective benefit of "low-microbial / neutropenic diets" is suggested to use in immunosuppressed patients. Traditionally, total parenteral nutrition (TPN) has been the chosen method for the nutritional support of patients undergoing HSCT. Secondly enteral nutrition (especially with enteral tube feeding - ETF) is an alternative method for nutritional support. It is important that dietary guidance for HSCT patients to minimize the risk of microbial exposure, optimize nutrient consumption and energy intake is very important. [ABSTRACT FROM AUTHOR]

Published
2013
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