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The gold-acid-co-catalyzed synthesis of nine series of fused azaheterocycles with structural diversity starting from the same synthons as readily available propargylic hydroperoxides and aromatic amines has been achieved. The overall tandem process consists in a gold-catalyzed hydroperoxide rearrangement/Michael reaction followed by a final acid-catalyzed cyclization., (© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Starting from β,γ-allendiols and α-allenic acetates, a chemo- and regiocontrolled palladium-catalyzed methodology has provided access to enantiopure 3,6-dihydropyrans that bear a buta-1,3-dienyl moiety. Thus, it has been demonstrated for the first time that the preparation of six-membered heterocycles through cross-coupling reactions of two different allenes can be accomplished. These heterocyclization/cross-coupling reactions have been developed experimentally and their mechanisms have additionally been investigated by a computational study., (Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

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We report herein full details of the first example of a Cope rearrangement in which the C3-C4 bond of the β-lactam nucleus is the central bond of the 1,5-hexadiene system, thus providing an easy and efficient entry to novel, and in some cases optically pure functionalized azocinones. [ABSTRACT FROM AUTHOR]